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Antimalarial, Anticancer, Antimicrobial activities and chemical constituents of essential oil from the aerial parts of Cyperus kyllingia Endl

Journal Article


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Abstract


  • The chemical constituents of the essential oil from Cyperus kyllingia Endl. were analyzed by a GC, GC-MS. Twenty-three compounds were identified, accounting for 93.75% of the total oil that consisted mainly of oxygenated sesquiterpenes (53.52%), particularly sesquiterpene hydrocarbons (38.97%), and carboxylic acid (1.26%). The most representative compounds were α-cadinol (19.32%), caryophyllene oxide (12.17%), α-muurolol (11.58%), α-humulene (9.85%), and α-atlantone (6.07%). The oil showed significant activities against Plasmodium falcipalum (K1, multi drug resistant strain) and NCI-H187 (Small Cell Lung Cancer) with the IC50 values of 7.52 and 7.72 μg/mL, respectively. The oil exhibited highly active against Staphylococcus aureus ATCC25923 and moderately active against Escherichia coli ATCC25922, Pseudomonas aeruginosa ATCC27553, Aspergillus flavus and Candida albicans. © Published 04 15/2011 EISSN: 1307-6167.

UOW Authors


  •   Khamsan, Sorachai (external author)
  •   Liawruangrath, Boonsom (external author)
  •   Liawruangrath, Saisunee (external author)
  •   Teerawutkulrag, Aphiwat (external author)
  •   Pyne, Stephen
  •   Garson, Mary J. (external author)

Publication Date


  • 2011

Citation


  • Khamsan, S., Liawruangrath, B., Liawruangrath, S., Teerawutkulrag, A., Pyne, S. G. & Garson, M. J. (2011). Antimalarial, Anticancer, Antimicrobial activities and chemical constituents of essential oil from the aerial parts of Cyperus kyllingia Endl. Records of Natural Products, 5 (4), 324-327.

Scopus Eid


  • 2-s2.0-79957612776

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=7112&context=scipapers

Ro Metadata Url


  • http://ro.uow.edu.au/scipapers/3770

Has Global Citation Frequency


Number Of Pages


  • 3

Start Page


  • 324

End Page


  • 327

Volume


  • 5

Issue


  • 4

Abstract


  • The chemical constituents of the essential oil from Cyperus kyllingia Endl. were analyzed by a GC, GC-MS. Twenty-three compounds were identified, accounting for 93.75% of the total oil that consisted mainly of oxygenated sesquiterpenes (53.52%), particularly sesquiterpene hydrocarbons (38.97%), and carboxylic acid (1.26%). The most representative compounds were α-cadinol (19.32%), caryophyllene oxide (12.17%), α-muurolol (11.58%), α-humulene (9.85%), and α-atlantone (6.07%). The oil showed significant activities against Plasmodium falcipalum (K1, multi drug resistant strain) and NCI-H187 (Small Cell Lung Cancer) with the IC50 values of 7.52 and 7.72 μg/mL, respectively. The oil exhibited highly active against Staphylococcus aureus ATCC25923 and moderately active against Escherichia coli ATCC25922, Pseudomonas aeruginosa ATCC27553, Aspergillus flavus and Candida albicans. © Published 04 15/2011 EISSN: 1307-6167.

UOW Authors


  •   Khamsan, Sorachai (external author)
  •   Liawruangrath, Boonsom (external author)
  •   Liawruangrath, Saisunee (external author)
  •   Teerawutkulrag, Aphiwat (external author)
  •   Pyne, Stephen
  •   Garson, Mary J. (external author)

Publication Date


  • 2011

Citation


  • Khamsan, S., Liawruangrath, B., Liawruangrath, S., Teerawutkulrag, A., Pyne, S. G. & Garson, M. J. (2011). Antimalarial, Anticancer, Antimicrobial activities and chemical constituents of essential oil from the aerial parts of Cyperus kyllingia Endl. Records of Natural Products, 5 (4), 324-327.

Scopus Eid


  • 2-s2.0-79957612776

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=7112&context=scipapers

Ro Metadata Url


  • http://ro.uow.edu.au/scipapers/3770

Has Global Citation Frequency


Number Of Pages


  • 3

Start Page


  • 324

End Page


  • 327

Volume


  • 5

Issue


  • 4