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Complete assignment of the 1H and 13C NMR spectra of antimicrobial 4-arylamino- 3-nitrocoumarin derivatives

Journal Article


Abstract


  • Herein, we describe the synthesis and complete assignment of the 1H and 13C NMR chemical shifts of a series of antimicrobial 4-arylamino-3-nitrocoumarin derivatives based on a combination of 1H and 13C NMR, 1H-1H-COSY, NOESY, HSQC and HMBC experiments. Conformational effects upon the chemical shifts of the coumarin moiety arising from the anisotropy of the aryl side group are briefly discussed. This study provides the first complete and fully assigned NMR data for this important group of antimicrobial compounds and bridges the gap existing in the literature with regard to NMR structural data for 4-arylamino-3-nitrocoumarins.

Authors


  •   Dekic, Vidoslav (external author)
  •   Radulovic, Niko (external author)
  •   Vukicevic, Rastko (external author)
  •   Dekic, Biljana (external author)
  •   Skropeta, Danielle
  •   Palic´, Radosav (external author)

Publication Date


  • 2010

Citation


  • Dekic, V., Radulovic, N., Vukicevic, R., Dekic, B., Skropeta, D. & Palic´, R. (2010). Complete assignment of the 1H and 13C NMR spectra of antimicrobial 4-arylamino- 3-nitrocoumarin derivatives. Magnetic Resonance in Chemistry, 48 (11), 896-902.

Scopus Eid


  • 2-s2.0-78649680583

Ro Metadata Url


  • http://ro.uow.edu.au/scipapers/5073

Number Of Pages


  • 6

Start Page


  • 896

End Page


  • 902

Volume


  • 48

Issue


  • 11

Place Of Publication


  • http://interscience.wiley.com/jpages/0749-1581

Abstract


  • Herein, we describe the synthesis and complete assignment of the 1H and 13C NMR chemical shifts of a series of antimicrobial 4-arylamino-3-nitrocoumarin derivatives based on a combination of 1H and 13C NMR, 1H-1H-COSY, NOESY, HSQC and HMBC experiments. Conformational effects upon the chemical shifts of the coumarin moiety arising from the anisotropy of the aryl side group are briefly discussed. This study provides the first complete and fully assigned NMR data for this important group of antimicrobial compounds and bridges the gap existing in the literature with regard to NMR structural data for 4-arylamino-3-nitrocoumarins.

Authors


  •   Dekic, Vidoslav (external author)
  •   Radulovic, Niko (external author)
  •   Vukicevic, Rastko (external author)
  •   Dekic, Biljana (external author)
  •   Skropeta, Danielle
  •   Palic´, Radosav (external author)

Publication Date


  • 2010

Citation


  • Dekic, V., Radulovic, N., Vukicevic, R., Dekic, B., Skropeta, D. & Palic´, R. (2010). Complete assignment of the 1H and 13C NMR spectra of antimicrobial 4-arylamino- 3-nitrocoumarin derivatives. Magnetic Resonance in Chemistry, 48 (11), 896-902.

Scopus Eid


  • 2-s2.0-78649680583

Ro Metadata Url


  • http://ro.uow.edu.au/scipapers/5073

Number Of Pages


  • 6

Start Page


  • 896

End Page


  • 902

Volume


  • 48

Issue


  • 11

Place Of Publication


  • http://interscience.wiley.com/jpages/0749-1581