Adolescence is a time of exploration of the self, and this exploration may
involve the use of alcohol and drugs. Sadly, for some, adolescence also
marks the first signs of a psychosis. The temporal proximity between
the onset of substance use and of psychosis has been the cause of much
debate. Here we review the association of alcohol, cannabis, stimulants,
and other drugs with psychosis, and we conclude that the use of cannabis
and the amphetamines significantly contributes to the risk of psychosis.