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Serotonin 2A receptor and its association with the pathology of schizophrenia

Journal Article


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Abstract


  • Dear Editor:

    Accumulated evidence suggests that serotonin 2A (5-HT2A) receptors

    are implicated in the pathology of schizophrenia. However the results

    remain inconclusive, particularly in the case of binding studies using

    postmortemtissue.We agreewith Dean's comment that our recent paper

    (Kang et al., 2009) reported a decrease in the density of [3H] ketanserin

    binding to the 5-HT2A receptors in the superior temporal gyrus (STG),

    which supported earlier findings in the planum temporal cortex (Pralong

    et al., 2000), despite Burnet et al. reporting previously that there was no

    change in [3H] ketanserin binding in the STG in schizophrenia (Burnet

    et al., 1996).............

Publication Date


  • 2009

Citation


  • Deng, C., Kang, K., Wang, Q. & Huang, X. (2009). Serotonin 2A receptor and its association with the pathology of schizophrenia. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 33 (8), 1585-1586.

Scopus Eid


  • 2-s2.0-71549118209

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=2406&context=smhpapers

Ro Metadata Url


  • http://ro.uow.edu.au/smhpapers/1388

Has Global Citation Frequency


Number Of Pages


  • 1

Start Page


  • 1585

End Page


  • 1586

Volume


  • 33

Issue


  • 8

Place Of Publication


  • United States

Abstract


  • Dear Editor:

    Accumulated evidence suggests that serotonin 2A (5-HT2A) receptors

    are implicated in the pathology of schizophrenia. However the results

    remain inconclusive, particularly in the case of binding studies using

    postmortemtissue.We agreewith Dean's comment that our recent paper

    (Kang et al., 2009) reported a decrease in the density of [3H] ketanserin

    binding to the 5-HT2A receptors in the superior temporal gyrus (STG),

    which supported earlier findings in the planum temporal cortex (Pralong

    et al., 2000), despite Burnet et al. reporting previously that there was no

    change in [3H] ketanserin binding in the STG in schizophrenia (Burnet

    et al., 1996).............

Publication Date


  • 2009

Citation


  • Deng, C., Kang, K., Wang, Q. & Huang, X. (2009). Serotonin 2A receptor and its association with the pathology of schizophrenia. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 33 (8), 1585-1586.

Scopus Eid


  • 2-s2.0-71549118209

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=2406&context=smhpapers

Ro Metadata Url


  • http://ro.uow.edu.au/smhpapers/1388

Has Global Citation Frequency


Number Of Pages


  • 1

Start Page


  • 1585

End Page


  • 1586

Volume


  • 33

Issue


  • 8

Place Of Publication


  • United States