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Effects of rTMS on an auditory oddball task: a pilot study of cortical plasticity and the EEG

Journal Article


Abstract


  • The objective of this study was to explore the effects of 1Hz repetitive transcranial magnetic stimulation (rTMS) applied to dorsal lateral prefrontal cortex (DLPFC) on both an EEG index of cortical excitation and inhibition, event-related desynchronization/ synchronization (ERDIS) and on the P300 component of an auditory oddball-induced ERP. Eight normal participants received 15 minutes of 1Hz rTMS at 110% of the resting motor threshold to right DLPFC. ERDIS of alpha and beta bands was measured during an auditory oddball task immediately before and after stimulation. There was significantly less alpha desynchronization post-TMS, and this effect was widespread excepting posterior midline sites. No changes were found to oddball-P300 amplitudes or latencies. In conclusion, the findings of less alpha desynchronization post-TMS are compatible with notions of slow rTMS causing a decrease in cortical excitation.

Authors


  •   Cooper, Nick (external author)
  •   Fitzgerald, Paul (external author)
  •   Croft, Rodney J.
  •   Upton, Daniel (external author)
  •   Segrave, Rebecca A. (external author)
  •   Daskalakis, Z J. (external author)
  •   Kulkarni, Jayashri (external author)

Publication Date


  • 2008

Citation


  • Cooper, N., Fitzgerald, P., Croft, R. J., Upton, D., Segrave, R. A., Daskalakis, Z. J. & Kulkarni, J. (2008). Effects of rTMS on an auditory oddball task: a pilot study of cortical plasticity and the EEG. Clinical EEG and Neuroscience, 39 (3), 139-143.

Scopus Eid


  • 2-s2.0-52249115360

Has Global Citation Frequency


Number Of Pages


  • 4

Start Page


  • 139

End Page


  • 143

Volume


  • 39

Issue


  • 3

Place Of Publication


  • United States

Abstract


  • The objective of this study was to explore the effects of 1Hz repetitive transcranial magnetic stimulation (rTMS) applied to dorsal lateral prefrontal cortex (DLPFC) on both an EEG index of cortical excitation and inhibition, event-related desynchronization/ synchronization (ERDIS) and on the P300 component of an auditory oddball-induced ERP. Eight normal participants received 15 minutes of 1Hz rTMS at 110% of the resting motor threshold to right DLPFC. ERDIS of alpha and beta bands was measured during an auditory oddball task immediately before and after stimulation. There was significantly less alpha desynchronization post-TMS, and this effect was widespread excepting posterior midline sites. No changes were found to oddball-P300 amplitudes or latencies. In conclusion, the findings of less alpha desynchronization post-TMS are compatible with notions of slow rTMS causing a decrease in cortical excitation.

Authors


  •   Cooper, Nick (external author)
  •   Fitzgerald, Paul (external author)
  •   Croft, Rodney J.
  •   Upton, Daniel (external author)
  •   Segrave, Rebecca A. (external author)
  •   Daskalakis, Z J. (external author)
  •   Kulkarni, Jayashri (external author)

Publication Date


  • 2008

Citation


  • Cooper, N., Fitzgerald, P., Croft, R. J., Upton, D., Segrave, R. A., Daskalakis, Z. J. & Kulkarni, J. (2008). Effects of rTMS on an auditory oddball task: a pilot study of cortical plasticity and the EEG. Clinical EEG and Neuroscience, 39 (3), 139-143.

Scopus Eid


  • 2-s2.0-52249115360

Has Global Citation Frequency


Number Of Pages


  • 4

Start Page


  • 139

End Page


  • 143

Volume


  • 39

Issue


  • 3

Place Of Publication


  • United States