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Aryl nitro reduction with iron powder or stannous chloride under ultrasonic irradiation

Journal Article


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Abstract


  • The selective reduction of aryl nitro compounds in the presence of sensitive functionalities, including halide, carbonyl, nitrile and ester substituents under ultrasonic irradiation at 35 kHz is reported in yields of 39-98%. Iron powder proved superior to stannous chloride with high tolerance of sensitive functional groups and high yields of the desired aryl amines in relatively short reaction times. Simple experimental procedure and purification also make the iron reduction of aryl nitro compounds advantageous over other methods of reduction.

Authors


  •   Gamble, Allan (external author)
  •   Garner, James A. (external author)
  •   Gordon, Christopher P. (external author)
  •   O'Connor, Sean (external author)
  •   Keller, Paul A.

Publication Date


  • 2007

Citation


  • Gamble, A., Garner, J. A., Gordon, C. P., O'Connor, S. & Keller, P. A. (2007). Aryl nitro reduction with iron powder or stannous chloride under ultrasonic irradiation. Synthetic Communications: an international journal for rapid communication of synthetic organic chem, 37 (16), 2777-2786.

Scopus Eid


  • 2-s2.0-34547962813

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=1174&context=scipapers

Ro Metadata Url


  • http://ro.uow.edu.au/scipapers/148

Number Of Pages


  • 9

Start Page


  • 2777

End Page


  • 2786

Volume


  • 37

Issue


  • 16

Place Of Publication


  • http://www.informaworld.com/smpp/title~content=g781333588~db=all

Abstract


  • The selective reduction of aryl nitro compounds in the presence of sensitive functionalities, including halide, carbonyl, nitrile and ester substituents under ultrasonic irradiation at 35 kHz is reported in yields of 39-98%. Iron powder proved superior to stannous chloride with high tolerance of sensitive functional groups and high yields of the desired aryl amines in relatively short reaction times. Simple experimental procedure and purification also make the iron reduction of aryl nitro compounds advantageous over other methods of reduction.

Authors


  •   Gamble, Allan (external author)
  •   Garner, James A. (external author)
  •   Gordon, Christopher P. (external author)
  •   O'Connor, Sean (external author)
  •   Keller, Paul A.

Publication Date


  • 2007

Citation


  • Gamble, A., Garner, J. A., Gordon, C. P., O'Connor, S. & Keller, P. A. (2007). Aryl nitro reduction with iron powder or stannous chloride under ultrasonic irradiation. Synthetic Communications: an international journal for rapid communication of synthetic organic chem, 37 (16), 2777-2786.

Scopus Eid


  • 2-s2.0-34547962813

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=1174&context=scipapers

Ro Metadata Url


  • http://ro.uow.edu.au/scipapers/148

Number Of Pages


  • 9

Start Page


  • 2777

End Page


  • 2786

Volume


  • 37

Issue


  • 16

Place Of Publication


  • http://www.informaworld.com/smpp/title~content=g781333588~db=all