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Synthesis and 3D printing of conducting alginate–polypyrrole ionomers

Journal Article


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Abstract


  • © 2020 by the authors. Licensee MDPI, Basel, Switzerland. Hydrogels composed of calcium cross-linked alginate are under investigation as bioinks for tissue engineering scaffolds due to their variable viscoelasticity, biocompatibility, and erodibility. Here, pyrrole was oxidatively polymerized in the presence of sodium alginate solutions to form ionomeric composites of various compositions. The IR spectroscopy shows that mild base is required to prevent the oxidant from attacking the alginate during the polymerization reaction. The resulting composites were isolated as dried thin films or cross-linked hydrogels and aerogels. The products were characterized by elemental analysis to determine polypyrrole incorporation, electrical conductivity measurements, and by SEM to determine changes in morphology or large-scale phase separation. Polypyrrole incorporation of up to twice the alginate (monomer versus monomer) provided materials amenable to 3D extrusion printing. The PC12 neuronal cells adhered and proliferated on the composites, demonstrating their biocompatibility and potential for tissue engineering applications.

Authors


  •   Wright, Cassandra (external author)
  •   Zhang, Binbin (external author)
  •   Chung, Johnson
  •   Pannell, Jonathan (external author)
  •   Kuester, Melissa (external author)
  •   Molino, Paul J.
  •   Hanks, Timothy (external author)

Publication Date


  • 2020

Published In


Citation


  • Wright, C., Zhang, B., Chung, J., Pannell, J., Kuester, M., Molino, P. & Hanks, T. (2020). Synthesis and 3D printing of conducting alginate–polypyrrole ionomers. Gels, 6 (2), 1-12.

Scopus Eid


  • 2-s2.0-85087375235

Ro Full-text Url


  • https://ro.uow.edu.au/cgi/viewcontent.cgi?article=5283&context=aiimpapers

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/4228

Number Of Pages


  • 11

Start Page


  • 1

End Page


  • 12

Volume


  • 6

Issue


  • 2

Place Of Publication


  • Switzerland

Abstract


  • © 2020 by the authors. Licensee MDPI, Basel, Switzerland. Hydrogels composed of calcium cross-linked alginate are under investigation as bioinks for tissue engineering scaffolds due to their variable viscoelasticity, biocompatibility, and erodibility. Here, pyrrole was oxidatively polymerized in the presence of sodium alginate solutions to form ionomeric composites of various compositions. The IR spectroscopy shows that mild base is required to prevent the oxidant from attacking the alginate during the polymerization reaction. The resulting composites were isolated as dried thin films or cross-linked hydrogels and aerogels. The products were characterized by elemental analysis to determine polypyrrole incorporation, electrical conductivity measurements, and by SEM to determine changes in morphology or large-scale phase separation. Polypyrrole incorporation of up to twice the alginate (monomer versus monomer) provided materials amenable to 3D extrusion printing. The PC12 neuronal cells adhered and proliferated on the composites, demonstrating their biocompatibility and potential for tissue engineering applications.

Authors


  •   Wright, Cassandra (external author)
  •   Zhang, Binbin (external author)
  •   Chung, Johnson
  •   Pannell, Jonathan (external author)
  •   Kuester, Melissa (external author)
  •   Molino, Paul J.
  •   Hanks, Timothy (external author)

Publication Date


  • 2020

Published In


Citation


  • Wright, C., Zhang, B., Chung, J., Pannell, J., Kuester, M., Molino, P. & Hanks, T. (2020). Synthesis and 3D printing of conducting alginate–polypyrrole ionomers. Gels, 6 (2), 1-12.

Scopus Eid


  • 2-s2.0-85087375235

Ro Full-text Url


  • https://ro.uow.edu.au/cgi/viewcontent.cgi?article=5283&context=aiimpapers

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/4228

Number Of Pages


  • 11

Start Page


  • 1

End Page


  • 12

Volume


  • 6

Issue


  • 2

Place Of Publication


  • Switzerland