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Multitechnology Biofabrication: A New Approach for the Manufacturing of Functional Tissue Structures?

Journal Article


Abstract


  • © 2020 Elsevier Ltd Most available 3D biofabrication technologies rely on single-component deposition methods, such as inkjet, extrusion, or light-assisted printing. It is unlikely that any of these technologies used individually would be able to replicate the complexity and functionality of living tissues. Recently, new biofabrication approaches have emerged that integrate multiple manufacturing technologies into a single biofabrication platform. This has led to fabricated structures with improved functionality. In this review, we provide a comprehensive overview of recent advances in the integration of different manufacturing technologies with the aim to fabricate more functional tissue structures. We provide our vision on the future of additive manufacturing (AM) technology, digital design, and the use of artificial intelligence (AI) in the field of biofabrication.

UOW Authors


  •   Castilho, Miguel (external author)
  •   de Ruijter, Mylene (external author)
  •   Beirne, Stephen
  •   Villette, Claire (external author)
  •   Ito, Keita (external author)
  •   Wallace, Gordon
  •   Malda, Jos (external author)

Publication Date


  • 2020

Citation


  • Castilho, M., de Ruijter, M., Beirne, S., Villette, C., Ito, K., Wallace, G. & Malda, J. (2020). Multitechnology Biofabrication: A New Approach for the Manufacturing of Functional Tissue Structures?. Trends in Biotechnology,

Scopus Eid


  • 2-s2.0-85085352428

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/4171

Place Of Publication


  • United Kingdom

Abstract


  • © 2020 Elsevier Ltd Most available 3D biofabrication technologies rely on single-component deposition methods, such as inkjet, extrusion, or light-assisted printing. It is unlikely that any of these technologies used individually would be able to replicate the complexity and functionality of living tissues. Recently, new biofabrication approaches have emerged that integrate multiple manufacturing technologies into a single biofabrication platform. This has led to fabricated structures with improved functionality. In this review, we provide a comprehensive overview of recent advances in the integration of different manufacturing technologies with the aim to fabricate more functional tissue structures. We provide our vision on the future of additive manufacturing (AM) technology, digital design, and the use of artificial intelligence (AI) in the field of biofabrication.

UOW Authors


  •   Castilho, Miguel (external author)
  •   de Ruijter, Mylene (external author)
  •   Beirne, Stephen
  •   Villette, Claire (external author)
  •   Ito, Keita (external author)
  •   Wallace, Gordon
  •   Malda, Jos (external author)

Publication Date


  • 2020

Citation


  • Castilho, M., de Ruijter, M., Beirne, S., Villette, C., Ito, K., Wallace, G. & Malda, J. (2020). Multitechnology Biofabrication: A New Approach for the Manufacturing of Functional Tissue Structures?. Trends in Biotechnology,

Scopus Eid


  • 2-s2.0-85085352428

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/4171

Place Of Publication


  • United Kingdom