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Hybrid Graphene/Conducting Polymer Strip Sensors for Sensitive and Selective Electrochemical Detection of Serotonin

Journal Article


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Abstract


  • © 2019 American Chemical Society. There is an urgent need for electrochemical sensor materials that exhibit electrochemically compliant properties while also retaining high durability under physiological conditions. Herein, we demonstrate a novel strip-style electrochemical sensor using reduced graphene oxide (rGO) and poly(ethylene dioxythiophene)/poly(styrene sulfonic acid) (PEDOT/PSS) nanocomposite films. The fabricated rGO-PEDOT/PSS sensor with and without nafion has shown an effective electrochemical response for both selectivity and sensitivity of the serotonin (5-hydroxytryptamine, 5-HT) neurotransmitter. The developed high-performance hybrid graphene/conducting polymer strip sensors are likely to find applications as chip electrochemical sensor devices for patients diagnosed with Alzheimer's disease.

Authors


  •   Al-Graiti, Wed (external author)
  •   Foroughi, Javad (external author)
  •   Liu, Yuqing (external author)
  •   Chen, Jun

Publication Date


  • 2019

Citation


  • Al-Graiti, W., Foroughi, J., Liu, Y. & Chen, J. (2019). Hybrid Graphene/Conducting Polymer Strip Sensors for Sensitive and Selective Electrochemical Detection of Serotonin. ACS Omega,

Scopus Eid


  • 2-s2.0-85077011567

Ro Full-text Url


  • https://ro.uow.edu.au/cgi/viewcontent.cgi?article=5028&context=aiimpapers

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/3973

Abstract


  • © 2019 American Chemical Society. There is an urgent need for electrochemical sensor materials that exhibit electrochemically compliant properties while also retaining high durability under physiological conditions. Herein, we demonstrate a novel strip-style electrochemical sensor using reduced graphene oxide (rGO) and poly(ethylene dioxythiophene)/poly(styrene sulfonic acid) (PEDOT/PSS) nanocomposite films. The fabricated rGO-PEDOT/PSS sensor with and without nafion has shown an effective electrochemical response for both selectivity and sensitivity of the serotonin (5-hydroxytryptamine, 5-HT) neurotransmitter. The developed high-performance hybrid graphene/conducting polymer strip sensors are likely to find applications as chip electrochemical sensor devices for patients diagnosed with Alzheimer's disease.

Authors


  •   Al-Graiti, Wed (external author)
  •   Foroughi, Javad (external author)
  •   Liu, Yuqing (external author)
  •   Chen, Jun

Publication Date


  • 2019

Citation


  • Al-Graiti, W., Foroughi, J., Liu, Y. & Chen, J. (2019). Hybrid Graphene/Conducting Polymer Strip Sensors for Sensitive and Selective Electrochemical Detection of Serotonin. ACS Omega,

Scopus Eid


  • 2-s2.0-85077011567

Ro Full-text Url


  • https://ro.uow.edu.au/cgi/viewcontent.cgi?article=5028&context=aiimpapers

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/3973