In this study, an aluminium single crystal was deformed by roll-bonding, and the through-thickness texture and microstructure were characterized by electron backscattered diffraction (EBSD). Matrix bands and transition bands developed at the macro-scale, and microbands formed at the lower scale. Moreover, the crystal plasticity finite element method (CPFEM) was used to model the experimentally observed macro- and micro-subdivision. Matrix bands were captured in the Globalmodel that had a coarse mesh, and Submodel was adopted to predict microbands by refining the mesh. Two smaller regions of interest were selected from the Globalmodel and they were reconstructed in the Submodel. The Submodel was finely meshed, and it was deformed by the displacement-solution saved in the Globalmodel. One primary set of microbands in matrix bands and two sets of microbands in transition bands were successfully predicted. The deformation history at two points were traced to investigate the formation of microbands. The dominance of microbands in the Submodel was found to be associated with slip activity in the Globalmodel, and the formation and crystallographic nature of microbands were studied.