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Fibre optic dosimetry in synchrotron microbeam radiation therapy

Journal Article


Abstract


  • Synchrotron microbeam radiation therapy is a novel pre-clinical therapy method that uses high brilliance, spatially fractionated, low energy x-rays to deliver a very high dose rate. A conventional spatial fractionation for these beams is 50 μm microbeam width at 400 μm peak-to-peak separation. To perform dosimetry on these beams, a dosimeter with a high spatial resolution is required. We present a plastic scintillator fibre optic dosimeter that has been demonstrated to be able to resolve the microbeam structure. The advantages of such a dosimeter is the water equivalence, passive components exposed to the radiation field, relatively inexpensive components and simple fabrication. We use cylindrical BC-400 plastic scintillator optically coupled to a 1 mm diameter core plastic optical fibre. BC-620 reflective paint was coated on the end of the probe to maximise the capture of light. A silicon photomultiplier (SensL MiniSM) was used to measure the light output of the probe. A 50 μm resolution probe and 20 μm probe was tested at the Australian Synchrotron, on the Imaging and Medical Beam-Line. We were able to resolve microbeams with both resolution probes. The depth dose measurements matched that of a Pinpoint ionisation chamber except for an over-response at shallow depth.

Publication Date


  • 2019

Citation


  • Archer, J., Li, E., Rosenfeld, A. B. & Lerch, M. (2019). Fibre optic dosimetry in synchrotron microbeam radiation therapy. Journal of Physics: Conference Series, 1154 (Conference 1), 1-4.

Scopus Eid


  • 2-s2.0-85064416842

Number Of Pages


  • 3

Start Page


  • 1

End Page


  • 4

Volume


  • 1154

Issue


  • Conference 1

Place Of Publication


  • United Kingdom

Abstract


  • Synchrotron microbeam radiation therapy is a novel pre-clinical therapy method that uses high brilliance, spatially fractionated, low energy x-rays to deliver a very high dose rate. A conventional spatial fractionation for these beams is 50 μm microbeam width at 400 μm peak-to-peak separation. To perform dosimetry on these beams, a dosimeter with a high spatial resolution is required. We present a plastic scintillator fibre optic dosimeter that has been demonstrated to be able to resolve the microbeam structure. The advantages of such a dosimeter is the water equivalence, passive components exposed to the radiation field, relatively inexpensive components and simple fabrication. We use cylindrical BC-400 plastic scintillator optically coupled to a 1 mm diameter core plastic optical fibre. BC-620 reflective paint was coated on the end of the probe to maximise the capture of light. A silicon photomultiplier (SensL MiniSM) was used to measure the light output of the probe. A 50 μm resolution probe and 20 μm probe was tested at the Australian Synchrotron, on the Imaging and Medical Beam-Line. We were able to resolve microbeams with both resolution probes. The depth dose measurements matched that of a Pinpoint ionisation chamber except for an over-response at shallow depth.

Publication Date


  • 2019

Citation


  • Archer, J., Li, E., Rosenfeld, A. B. & Lerch, M. (2019). Fibre optic dosimetry in synchrotron microbeam radiation therapy. Journal of Physics: Conference Series, 1154 (Conference 1), 1-4.

Scopus Eid


  • 2-s2.0-85064416842

Number Of Pages


  • 3

Start Page


  • 1

End Page


  • 4

Volume


  • 1154

Issue


  • Conference 1

Place Of Publication


  • United Kingdom