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Development of LEU-based targets for radiopharmaceutical manufacturing: A review

Journal Article


Abstract


  • Mo is an essential medical isotope that comprises of at least 70% of radioactive procedures globally. Currently an essential component of 99 Mo manufacturing is the uranium target from which 99 Mo is produced by fission. As the world moves towards low enriched uranium (LEU) targets due to non-proliferation concerns it is becoming of interest to find methods to increase the efficiency of the LEU targets in order to reduce the ever increasing nuclear waste levels of which a long term solution for disposal or treatment has yet to be satisfactorily found. Advantages and disadvantages of various target designs are investigated and discussed along current disposal and reprocessing methods. The idea of a reusable target is introduced as a way forward in reducing the nuclear waste burden for future generations.

UOW Authors


  •   Raposio, Robert (external author)
  •   Thorogood, Gordon (external author)
  •   Czerwinski, Ken (external author)
  •   Rosenfeld, Anatoly B.

Publication Date


  • 2019

Citation


  • Raposio, R., Thorogood, G., Czerwinski, K. & Rozenfeld, A. (2019). Development of LEU-based targets for radiopharmaceutical manufacturing: A review. Applied Radiation and Isotopes, 148 225-231.

Scopus Eid


  • 2-s2.0-85064247041

Number Of Pages


  • 6

Start Page


  • 225

End Page


  • 231

Volume


  • 148

Place Of Publication


  • United Kingdom

Abstract


  • Mo is an essential medical isotope that comprises of at least 70% of radioactive procedures globally. Currently an essential component of 99 Mo manufacturing is the uranium target from which 99 Mo is produced by fission. As the world moves towards low enriched uranium (LEU) targets due to non-proliferation concerns it is becoming of interest to find methods to increase the efficiency of the LEU targets in order to reduce the ever increasing nuclear waste levels of which a long term solution for disposal or treatment has yet to be satisfactorily found. Advantages and disadvantages of various target designs are investigated and discussed along current disposal and reprocessing methods. The idea of a reusable target is introduced as a way forward in reducing the nuclear waste burden for future generations.

UOW Authors


  •   Raposio, Robert (external author)
  •   Thorogood, Gordon (external author)
  •   Czerwinski, Ken (external author)
  •   Rosenfeld, Anatoly B.

Publication Date


  • 2019

Citation


  • Raposio, R., Thorogood, G., Czerwinski, K. & Rozenfeld, A. (2019). Development of LEU-based targets for radiopharmaceutical manufacturing: A review. Applied Radiation and Isotopes, 148 225-231.

Scopus Eid


  • 2-s2.0-85064247041

Number Of Pages


  • 6

Start Page


  • 225

End Page


  • 231

Volume


  • 148

Place Of Publication


  • United Kingdom