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Opioid Agonist Treatment for Patients With Dependence on Prescription Opioids

Journal Article


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Abstract


  • Clinical Question Are different opioid agonist treatments (eg, methadone vs buprenorphine) associated with differences in efficacy for treating prescription opioid dependence, and is long-term maintenance of opioid agonist treatment associated with differences in efficacy compared with opioid taper or psychological treatments alone?

    Bottom Line For patients who are dependent on prescription opioids, long-term maintenance of opioid agonists is associated with less prescription opioid use and better adherence to medication and psychological therapies for opioid dependence compared with opioid taper or psychological treatments alone. Methadone maintenance was not associated with differences in therapeutic efficacy compared with buprenorphine maintenance treatment. Evidence quality was low to moderate.

Authors


  •   Nielsen, Suzanne (external author)
  •   Larance, Briony
  •   Lintzeris, Nicholas (external author)

Publication Date


  • 2017

Citation


  • Nielsen, S., Larance, B. & Lintzeris, N. (2017). Opioid Agonist Treatment for Patients With Dependence on Prescription Opioids. JAMA: Journal of the American Medical Association, 317 (9), 967-968.

Ro Full-text Url


  • https://ro.uow.edu.au/cgi/viewcontent.cgi?article=5199&context=sspapers

Ro Metadata Url


  • http://ro.uow.edu.au/sspapers/4174

Number Of Pages


  • 1

Start Page


  • 967

End Page


  • 968

Volume


  • 317

Issue


  • 9

Place Of Publication


  • United States

Abstract


  • Clinical Question Are different opioid agonist treatments (eg, methadone vs buprenorphine) associated with differences in efficacy for treating prescription opioid dependence, and is long-term maintenance of opioid agonist treatment associated with differences in efficacy compared with opioid taper or psychological treatments alone?

    Bottom Line For patients who are dependent on prescription opioids, long-term maintenance of opioid agonists is associated with less prescription opioid use and better adherence to medication and psychological therapies for opioid dependence compared with opioid taper or psychological treatments alone. Methadone maintenance was not associated with differences in therapeutic efficacy compared with buprenorphine maintenance treatment. Evidence quality was low to moderate.

Authors


  •   Nielsen, Suzanne (external author)
  •   Larance, Briony
  •   Lintzeris, Nicholas (external author)

Publication Date


  • 2017

Citation


  • Nielsen, S., Larance, B. & Lintzeris, N. (2017). Opioid Agonist Treatment for Patients With Dependence on Prescription Opioids. JAMA: Journal of the American Medical Association, 317 (9), 967-968.

Ro Full-text Url


  • https://ro.uow.edu.au/cgi/viewcontent.cgi?article=5199&context=sspapers

Ro Metadata Url


  • http://ro.uow.edu.au/sspapers/4174

Number Of Pages


  • 1

Start Page


  • 967

End Page


  • 968

Volume


  • 317

Issue


  • 9

Place Of Publication


  • United States