Aim of the study: This study aimed to systematically synthesise the body of literature examining associations between neighbourhood socioeconomic disadvantage and serious mental illness (SMI) – type 2 diabetes (T2D) comorbidity. Understanding these associations would be useful in developing evidence based holistic interventions and health care policies.
Methods: We conducted an electronic search of four databases: PubMed; Scopus; Medline; and Web of Science. Studies were considered eligible if they were published in English, peer reviewed, quantitative, and focussed on the association between neighbourhood disadvantage and SMI-T2D comorbidity. Study conduct and reporting complied with PRISMA guidelines, and the protocol is available at PROSPERO (CRD42017083483).
Results: The one eligible study identified reported a higher burden of T2D in persons with SMI, but provided only a tentative support for the association between neighbourhood disadvantage and SMI –T2D comorbidity.
Conclusion: Research into neighbourhood effects on SMI-T2D comorbidity is still in its infancy and the available evidence inconclusive. This points to an urgent need for attention to the knowledge gap in this important area of population health. Further research is needed to understand the health resource implications of the association between neighbourhood deprivation and SMI-T2D comorbidity, and the causal pathways linking them.