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The role of resting-state EEG localized activation and central nervous system arousal in executive function performance in children with Attention-Deficit/Hyperactivity Disorder

Journal Article


Abstract


  • © 2018 International Federation of Clinical Neurophysiology Objective: This study explored the relationships between resting-state electroencephalogram (RS-EEG) localized activation and two important types of executive functions (EF) to extend the prognostic utilization of RS-EEG in children with Attention-Deficit/Hyperactivity Disorder (AD/HD). Also, the role of central nervous system (CNS) arousal in the relationships was examined. Methods: Fifty-eight children with AD/HD participated in the study. RS-EEG localized activation was derived from spectral power differences between EEG in eyes-closed and eyes-open conditions. CNS arousal was measured based on alpha band power. Common and everyday EF scores were obtained as EF outcomes. Results: Frontal delta activation predicted common EF ability and posterior alpha activation predicted everyday EF. A serial mediation analysis found that lower CNS baseline arousal was related to greater arousal and delta activation in series, which in turn related to worse common EF. A follow-up study found that baseline arousal was related to larger interference cost. Conclusions: RS-EEG is indicative of individual differences in two important types of EF in children with AD/HD. Lower CNS arousal may be a driving force for the poorer common EF performance. Significance: The current study supports prognostic utilization of RS-EEG and AD/HD models that take resting brain activity into consideration in children with AD/HD.

Authors


  •   Zhang, Dawei (external author)
  •   Johnstone, Stuart J.
  •   Roodenrys, Steven
  •   Luo, Xiangsheng (external author)
  •   Li, Hui (external author)
  •   Wang, Encong (external author)
  •   Zhao, Qihua (external author)
  •   Song, Yan (external author)
  •   Liu, Lu (external author)
  •   Qian, Qiujin (external author)
  •   Wang, Yufeng (external author)
  •   Sun, Li (external author)

Publication Date


  • 2018

Citation


  • Zhang, D., Johnstone, S., Roodenrys, S., Luo, X., Li, H., Wang, E., Zhao, Q., Song, Y., Liu, L., Qian, Q., Wang, Y. & Sun, L. (2018). The role of resting-state EEG localized activation and central nervous system arousal in executive function performance in children with Attention-Deficit/Hyperactivity Disorder. Clinical Neurophysiology, 129 (6), 1192-1200.

Scopus Eid


  • 2-s2.0-85045571530

Ro Metadata Url


  • http://ro.uow.edu.au/sspapers/3650

Number Of Pages


  • 8

Start Page


  • 1192

End Page


  • 1200

Volume


  • 129

Issue


  • 6

Place Of Publication


  • Ireland

Abstract


  • © 2018 International Federation of Clinical Neurophysiology Objective: This study explored the relationships between resting-state electroencephalogram (RS-EEG) localized activation and two important types of executive functions (EF) to extend the prognostic utilization of RS-EEG in children with Attention-Deficit/Hyperactivity Disorder (AD/HD). Also, the role of central nervous system (CNS) arousal in the relationships was examined. Methods: Fifty-eight children with AD/HD participated in the study. RS-EEG localized activation was derived from spectral power differences between EEG in eyes-closed and eyes-open conditions. CNS arousal was measured based on alpha band power. Common and everyday EF scores were obtained as EF outcomes. Results: Frontal delta activation predicted common EF ability and posterior alpha activation predicted everyday EF. A serial mediation analysis found that lower CNS baseline arousal was related to greater arousal and delta activation in series, which in turn related to worse common EF. A follow-up study found that baseline arousal was related to larger interference cost. Conclusions: RS-EEG is indicative of individual differences in two important types of EF in children with AD/HD. Lower CNS arousal may be a driving force for the poorer common EF performance. Significance: The current study supports prognostic utilization of RS-EEG and AD/HD models that take resting brain activity into consideration in children with AD/HD.

Authors


  •   Zhang, Dawei (external author)
  •   Johnstone, Stuart J.
  •   Roodenrys, Steven
  •   Luo, Xiangsheng (external author)
  •   Li, Hui (external author)
  •   Wang, Encong (external author)
  •   Zhao, Qihua (external author)
  •   Song, Yan (external author)
  •   Liu, Lu (external author)
  •   Qian, Qiujin (external author)
  •   Wang, Yufeng (external author)
  •   Sun, Li (external author)

Publication Date


  • 2018

Citation


  • Zhang, D., Johnstone, S., Roodenrys, S., Luo, X., Li, H., Wang, E., Zhao, Q., Song, Y., Liu, L., Qian, Q., Wang, Y. & Sun, L. (2018). The role of resting-state EEG localized activation and central nervous system arousal in executive function performance in children with Attention-Deficit/Hyperactivity Disorder. Clinical Neurophysiology, 129 (6), 1192-1200.

Scopus Eid


  • 2-s2.0-85045571530

Ro Metadata Url


  • http://ro.uow.edu.au/sspapers/3650

Number Of Pages


  • 8

Start Page


  • 1192

End Page


  • 1200

Volume


  • 129

Issue


  • 6

Place Of Publication


  • Ireland