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Suction-enhanced siphon valves for centrifugal microfluidic platforms

Journal Article


Abstract


  • In traditional centrifugal microfluidic platforms

    pumping is restricted to outward fluid flow, resulting in

    potential real estate issues for embedding complex microsystems.

    To overcome the limitation, researchers utilize

    hydrophilic channels to force liquids short distances back

    toward the disk center. However, most polymers used for

    CD fabrication are natively hydrophobic, and creating

    hydrophilic conditions requires surface treatments/specialized

    materials that pose unique challenges to manufacturing

    and use. This work describes a novel technology that

    enjoys the advantages of hydrophilic fluidics on a hydrophobic

    disk device constructed from untreated polycarbonate

    plastic. The method, termed suction-enhanced

    siphoning, is based on exploiting the non-linear hydrostatic

    pressure profile and related pressure drop created along the

    length of a rotating microchannel. Theoretical analysis as

    well as experimental validation of the system is provided.

    In addition, we demonstrate the use of the hydrostatic

    pressure pump as a new method for priming hydrophobicbased

    siphon structures. The development of such techniques

    for hydrophobic fluidics advances the capabilities of

    the centrifugal microfluidic platform while remaining true

    to the goal of creating disposable polymer devices using

    feasible manufacturing schemes.

Authors


  •   Gorkin III, Robert A.
  •   Soroori, Salar (external author)
  •   Southard, William (external author)
  •   Clime, Liviu (external author)
  •   Veres, Teodor (external author)
  •   Kido, Horacio (external author)
  •   Kulinsky, Lawrence (external author)
  •   Madou, Marc (external author)

Publication Date


  • 2012

Citation


  • Gorkin , R., Soroori, S., Southard, W., Clime, L., Veres, T., Kido, H., Kulinsky, L. & Madou, M. (2012). Suction-enhanced siphon valves for centrifugal microfluidic platforms. Microfluidics and Nanofluidics, 12 (1-4), 345-354.

Scopus Eid


  • 2-s2.0-84856230361

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/3051

Has Global Citation Frequency


Number Of Pages


  • 9

Start Page


  • 345

End Page


  • 354

Volume


  • 12

Issue


  • 1-4

Place Of Publication


  • Germany

Abstract


  • In traditional centrifugal microfluidic platforms

    pumping is restricted to outward fluid flow, resulting in

    potential real estate issues for embedding complex microsystems.

    To overcome the limitation, researchers utilize

    hydrophilic channels to force liquids short distances back

    toward the disk center. However, most polymers used for

    CD fabrication are natively hydrophobic, and creating

    hydrophilic conditions requires surface treatments/specialized

    materials that pose unique challenges to manufacturing

    and use. This work describes a novel technology that

    enjoys the advantages of hydrophilic fluidics on a hydrophobic

    disk device constructed from untreated polycarbonate

    plastic. The method, termed suction-enhanced

    siphoning, is based on exploiting the non-linear hydrostatic

    pressure profile and related pressure drop created along the

    length of a rotating microchannel. Theoretical analysis as

    well as experimental validation of the system is provided.

    In addition, we demonstrate the use of the hydrostatic

    pressure pump as a new method for priming hydrophobicbased

    siphon structures. The development of such techniques

    for hydrophobic fluidics advances the capabilities of

    the centrifugal microfluidic platform while remaining true

    to the goal of creating disposable polymer devices using

    feasible manufacturing schemes.

Authors


  •   Gorkin III, Robert A.
  •   Soroori, Salar (external author)
  •   Southard, William (external author)
  •   Clime, Liviu (external author)
  •   Veres, Teodor (external author)
  •   Kido, Horacio (external author)
  •   Kulinsky, Lawrence (external author)
  •   Madou, Marc (external author)

Publication Date


  • 2012

Citation


  • Gorkin , R., Soroori, S., Southard, W., Clime, L., Veres, T., Kido, H., Kulinsky, L. & Madou, M. (2012). Suction-enhanced siphon valves for centrifugal microfluidic platforms. Microfluidics and Nanofluidics, 12 (1-4), 345-354.

Scopus Eid


  • 2-s2.0-84856230361

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/3051

Has Global Citation Frequency


Number Of Pages


  • 9

Start Page


  • 345

End Page


  • 354

Volume


  • 12

Issue


  • 1-4

Place Of Publication


  • Germany