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Mesoporous Iron Oxide Synthesized Using Poly(styrene-b-acrylic acid-b-ethylene glycol) Block Copolymer Micelles as Templates for Colorimetric and Electrochemical Detection of Glucose

Journal Article


Abstract


  • Herein, we report the soft-templated preparation of mesoporous iron oxide using an asymmetric poly(styrene-b-acrylic acid-b-ethylene glycol) (PS-b-PAA-b-PEG) triblock copolymer. This polymer forms a micelle consisting of a PS core, a PAA shell, and a PEG corona in aqueous solutions, which can serve as a soft template. The mesoporous iron oxide obtained at an optimized calcination temperature of 400 °C exhibited an average pore diameter of 39 nm, with large specific surface area and pore volume of 86.9 m2 g–1 and 0.218 cm3 g–1, respectively. The as-prepared mesoporous iron oxide materials showed intrinsic peroxidase-like activities toward the catalytic oxidation of 3,3′,5,5′-tertamethylbenzidine (TMB) in the presence of hydrogen peroxide (H2O2). This mimetic feature was further exploited to develop a simple colorimetric (naked-eye) and electrochemical assay for the detection of glucose. Both our colorimetric (naked-eye and UV–vis) and electrochemical assays estimated the glucose concentration to be in the linear range from 1.0 μM to 100 μM with a detection limit of 1.0 μM. We envisage that our integrated detection platform for H2O2 and glucose will find a wide range of applications in developing various biosensors in the field of personalized medicine, food-safety detection, environmental-pollution control, and agro-biotechnology.

UOW Authors


  •   Tanaka, Shunsuke (external author)
  •   Kaneti, Yusuf (external author)
  •   Bhattacharjee, Ripon (external author)
  •   Islam, Md Nazmul (external author)
  •   Nakahata, Rina (external author)
  •   Abdullah, Nawfel (external author)
  •   Yusa, Shin-ichi (external author)
  •   Nguyen, Nam-Trung (external author)
  •   Shiddiky, Muhammad J. A. (external author)
  •   Yamauchi, Yusuke (external author)
  •   Hossain, Md Shahriar

Publication Date


  • 2018

Citation


  • Tanaka, S., Kaneti, Y., Bhattacharjee, R., Islam, M., Nakahata, R., Abdullah, N., Yusa, S., Nguyen, N., Shiddiky, M. J. A., Yamauchi, Y. & Hossain, M. A. (2018). Mesoporous Iron Oxide Synthesized Using Poly(styrene-b-acrylic acid-b-ethylene glycol) Block Copolymer Micelles as Templates for Colorimetric and Electrochemical Detection of Glucose. Acs Applied Materials & Interfaces, 10 (1), 1039-1049.

Scopus Eid


  • 2-s2.0-85038630300

Number Of Pages


  • 10

Start Page


  • 1039

End Page


  • 1049

Volume


  • 10

Issue


  • 1

Place Of Publication


  • United States

Abstract


  • Herein, we report the soft-templated preparation of mesoporous iron oxide using an asymmetric poly(styrene-b-acrylic acid-b-ethylene glycol) (PS-b-PAA-b-PEG) triblock copolymer. This polymer forms a micelle consisting of a PS core, a PAA shell, and a PEG corona in aqueous solutions, which can serve as a soft template. The mesoporous iron oxide obtained at an optimized calcination temperature of 400 °C exhibited an average pore diameter of 39 nm, with large specific surface area and pore volume of 86.9 m2 g–1 and 0.218 cm3 g–1, respectively. The as-prepared mesoporous iron oxide materials showed intrinsic peroxidase-like activities toward the catalytic oxidation of 3,3′,5,5′-tertamethylbenzidine (TMB) in the presence of hydrogen peroxide (H2O2). This mimetic feature was further exploited to develop a simple colorimetric (naked-eye) and electrochemical assay for the detection of glucose. Both our colorimetric (naked-eye and UV–vis) and electrochemical assays estimated the glucose concentration to be in the linear range from 1.0 μM to 100 μM with a detection limit of 1.0 μM. We envisage that our integrated detection platform for H2O2 and glucose will find a wide range of applications in developing various biosensors in the field of personalized medicine, food-safety detection, environmental-pollution control, and agro-biotechnology.

UOW Authors


  •   Tanaka, Shunsuke (external author)
  •   Kaneti, Yusuf (external author)
  •   Bhattacharjee, Ripon (external author)
  •   Islam, Md Nazmul (external author)
  •   Nakahata, Rina (external author)
  •   Abdullah, Nawfel (external author)
  •   Yusa, Shin-ichi (external author)
  •   Nguyen, Nam-Trung (external author)
  •   Shiddiky, Muhammad J. A. (external author)
  •   Yamauchi, Yusuke (external author)
  •   Hossain, Md Shahriar

Publication Date


  • 2018

Citation


  • Tanaka, S., Kaneti, Y., Bhattacharjee, R., Islam, M., Nakahata, R., Abdullah, N., Yusa, S., Nguyen, N., Shiddiky, M. J. A., Yamauchi, Y. & Hossain, M. A. (2018). Mesoporous Iron Oxide Synthesized Using Poly(styrene-b-acrylic acid-b-ethylene glycol) Block Copolymer Micelles as Templates for Colorimetric and Electrochemical Detection of Glucose. Acs Applied Materials & Interfaces, 10 (1), 1039-1049.

Scopus Eid


  • 2-s2.0-85038630300

Number Of Pages


  • 10

Start Page


  • 1039

End Page


  • 1049

Volume


  • 10

Issue


  • 1

Place Of Publication


  • United States