Abstract
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Mechanical perturbations to either the lung tissue or the chest wall can have deleterious effects upon
thoraco-pulmonary mechanics, thereby modifying the work of breathing and possibly leading to respiratorymuscle
fatigue. Thoracic loading, which is the most common form of ambulatory load carriage, is one example
whereby an increase in the overall physiological strain is accompanied by modified, and sometimes impeded
ventilation. However, the combined effects of the restrictive and inertial forces accompanying thoracic loading
on the elastic properties of the entire respiratory system have not previously been evaluated. Therefore, we
assessed the impact of thoracic loads on the static compliance of the lung tissue (Cst(l)), the chest wall (Cst(w))
and the total respiratory system (Cst(rs)), by varying both the size and distribution of loads around the chest wall.