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Vertical Nanowire Electrode Arrays as Novel Electrochemical Label-Free Immunosensors

Journal Article


Abstract


  • A new method for the fabrication of a label-free electrochemical immunosensor based on vertical nanowires (VNWs) is proposed. The VNWs are functionalized to detect antibodies against a major astrocytic structural protein component, glial fibrillary acidic protein (GFAP). It is revealed that the interaction of GFAP-antibody with functionalized VNWs leads to a clear change in device conductance and the corresponding capacitance.

Authors


  •   Nasr, Babak (external author)
  •   Chana, Gursharan (external author)
  •   Lee, Ting Ting (external author)
  •   Nguyen, Thanh (external author)
  •   Abeyrathne, Chathurika (external author)
  •   D'Abaco, Giovanna (external author)
  •   Dottori, Mirella
  •   Skafidas, Efstratios (external author)

Publication Date


  • 2015

Published In


Citation


  • Nasr, B., Chana, G., Lee, T., Nguyen, T., Abeyrathne, C., D'Abaco, G. M., Dottori, M. & Skafidas, E. (2015). Vertical Nanowire Electrode Arrays as Novel Electrochemical Label-Free Immunosensors. Small, 11 (24), 2862-2868.

Scopus Eid


  • 2-s2.0-84935864314

Ro Metadata Url


  • http://ro.uow.edu.au/ihmri/1159

Has Global Citation Frequency


Number Of Pages


  • 6

Start Page


  • 2862

End Page


  • 2868

Volume


  • 11

Issue


  • 24

Place Of Publication


  • Germany

Abstract


  • A new method for the fabrication of a label-free electrochemical immunosensor based on vertical nanowires (VNWs) is proposed. The VNWs are functionalized to detect antibodies against a major astrocytic structural protein component, glial fibrillary acidic protein (GFAP). It is revealed that the interaction of GFAP-antibody with functionalized VNWs leads to a clear change in device conductance and the corresponding capacitance.

Authors


  •   Nasr, Babak (external author)
  •   Chana, Gursharan (external author)
  •   Lee, Ting Ting (external author)
  •   Nguyen, Thanh (external author)
  •   Abeyrathne, Chathurika (external author)
  •   D'Abaco, Giovanna (external author)
  •   Dottori, Mirella
  •   Skafidas, Efstratios (external author)

Publication Date


  • 2015

Published In


Citation


  • Nasr, B., Chana, G., Lee, T., Nguyen, T., Abeyrathne, C., D'Abaco, G. M., Dottori, M. & Skafidas, E. (2015). Vertical Nanowire Electrode Arrays as Novel Electrochemical Label-Free Immunosensors. Small, 11 (24), 2862-2868.

Scopus Eid


  • 2-s2.0-84935864314

Ro Metadata Url


  • http://ro.uow.edu.au/ihmri/1159

Has Global Citation Frequency


Number Of Pages


  • 6

Start Page


  • 2862

End Page


  • 2868

Volume


  • 11

Issue


  • 24

Place Of Publication


  • Germany