The objective of this review highlight the place of lithium amidst the galaxy of medications used in the treatment of bipolar disorder and the accumulated evidence to support the rationale of lithium in taking up the pivotal position. In addition, this will also highlight the various factors that determine the prescription practices as relent in psychotropic medications, lithium in particular.
Selective literature review using the commonly available search engine (Medline, Psychinfo,embase) highlighting the objectives will be used.
Results / Discussion
Far more data are available to support the utility of lithium in the maintenance treatment
of Bipolar disorder than for all the other commonly prescribed agents combined. Lithium is the
prophylactic therapy against which all other novel therapies still are judged. There is a need to
integrate new developments into standards of practice, such that the greater costs of the newer therapies to patients and society are realistically weighed against benefits, and the potential side effects of these therapies are minimized.: Although Lithium therapy is a lifelong experience for many patients with Bipolar Disorder, the frequency of its use has been on the decline due to unrelated factors.