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Cell-shaped silicon-on-insulator microdosimeters: characterization and response to 239PuBe irradiations

Journal Article


Abstract


  • This work tested the feasibility of a silicon-on-insulator microdosimeter, which mimics the size and shape of specific cells within the human body, to determine dose equivalent from neutron irradiation. The microdosimeters were analyzed in terms of their basic diode characteristics, i.e., leakage current as a function of bias voltage. Lineal energy spectra were acquired using two different converter layers placed atop the microdosimeter: a tissue-substitute converter made from high-density polyethylene, and a boron converter consisting of epoxy coated with boron powder. The spectra were then converted into absorbed dose and dose equivalent. Experimental results were compared to Monte Carlo simulations of the neutron irradiations, revealing good agreement. Uncertainty in the dose equivalent determinations was 7.5% when using the cell-shaped microdosimeter with the tissue-substitute converter and 13.1% when using the boron converter. This work confirmed that the SOI approach to cell-mimicking microdosimetry is feasible.

UOW Authors


  •   Mazza, Anthony (external author)
  •   Newhauser, Wayne (external author)
  •   Pittman, Stephen (external author)
  •   Halloran, Andrew (external author)
  •   Maggi, Paul (external author)
  •   Tran, Linh T.
  •   Gila, Brent (external author)
  •   Rosenfeld, Anatoly B.
  •   Ziegler, James F. (external author)

Publication Date


  • 2017

Citation


  • Mazza, A., Newhauser, W., Pittman, S., Halloran, A., Maggi, P., Tran, L., Gila, B., Rosenfeld, A. & Ziegler, J. (2017). Cell-shaped silicon-on-insulator microdosimeters: characterization and response to 239PuBe irradiations. Australasian Physical and Engineering Sciences in Medicine, 40 (3), 667-673.

Scopus Eid


  • 2-s2.0-85028958112

Number Of Pages


  • 6

Start Page


  • 667

End Page


  • 673

Volume


  • 40

Issue


  • 3

Place Of Publication


  • Netherlands

Abstract


  • This work tested the feasibility of a silicon-on-insulator microdosimeter, which mimics the size and shape of specific cells within the human body, to determine dose equivalent from neutron irradiation. The microdosimeters were analyzed in terms of their basic diode characteristics, i.e., leakage current as a function of bias voltage. Lineal energy spectra were acquired using two different converter layers placed atop the microdosimeter: a tissue-substitute converter made from high-density polyethylene, and a boron converter consisting of epoxy coated with boron powder. The spectra were then converted into absorbed dose and dose equivalent. Experimental results were compared to Monte Carlo simulations of the neutron irradiations, revealing good agreement. Uncertainty in the dose equivalent determinations was 7.5% when using the cell-shaped microdosimeter with the tissue-substitute converter and 13.1% when using the boron converter. This work confirmed that the SOI approach to cell-mimicking microdosimetry is feasible.

UOW Authors


  •   Mazza, Anthony (external author)
  •   Newhauser, Wayne (external author)
  •   Pittman, Stephen (external author)
  •   Halloran, Andrew (external author)
  •   Maggi, Paul (external author)
  •   Tran, Linh T.
  •   Gila, Brent (external author)
  •   Rosenfeld, Anatoly B.
  •   Ziegler, James F. (external author)

Publication Date


  • 2017

Citation


  • Mazza, A., Newhauser, W., Pittman, S., Halloran, A., Maggi, P., Tran, L., Gila, B., Rosenfeld, A. & Ziegler, J. (2017). Cell-shaped silicon-on-insulator microdosimeters: characterization and response to 239PuBe irradiations. Australasian Physical and Engineering Sciences in Medicine, 40 (3), 667-673.

Scopus Eid


  • 2-s2.0-85028958112

Number Of Pages


  • 6

Start Page


  • 667

End Page


  • 673

Volume


  • 40

Issue


  • 3

Place Of Publication


  • Netherlands