Being competitive is a must for a country in the rapidly changing world economies. As parts of the new economic bloc, Asian Economic Community (AEC), the member countries need to ensure that their national economic and social development plans include relevant projects in order to take advantage from being members of the groups. Despite, the food safety is not new in the Western world, it is considered new in Asian countries. Food safety and control are indeed relevant parts for each government to regulate and control in order to meet the world standard. Therefore, the governments need to provide knowledge to and educate those related stakeholders on these particular issues as well as provide up-to-date regulation and control system. This study hence aims to explore the perception and attitude on food safety issues in Thailand from main stakeholders of three Thai provinces (Mukdahan, Khon Kaen, and Kalasin) in the East-West Economic Corridor (EWEC) in order to better understand any food safety issues that may impact on how those food safety regulation and control are implemented. Therefore the qualitative research approach was appropriately selected including documentary research and in-depth interviews. The finding shows that the food safety’s market situation in Thailand aligns with the Thai government policy on food safety. Although the main perception and attitude of related people on food safety control at each province are similar, some practical details in each province are different. The related government agencies need to ensure that all stakeholders are on the same page to ensure that food safety regulation and control are implemented.