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Gold-loaded nanoporous superparamagnetic nanocubes for catalytic signal amplification in detecting miRNA

Journal Article


Abstract

  • This paper reports the development of a nonenzymatic, amplificationfree,

    and sensitive platform for the detection of microRNA based on a

    new class of electrocatalytically active superparamagnetic gold-loaded

    nanoporous iron oxide nanocubes (Au@NPFe2O3NC). The assay showed

    an excellent detection sensitivity down to 100 fM and specificity towards

    the analysis of miR-21 in cell lines and tissue samples derived from

    patients with oesophageal squamous-cell carcinoma (ESCC).

UOW Authors

  •   Masud, Mostafa (external author)
  •   Islam, Md Nazmul (external author)
  •   Haque, Md Hakimul. (external author)
  •   Tanaka, Shunsuke (external author)
  •   Gopalan, Vinod (external author)
  •   Alici, Gursel
  •   Nguyen, Nam-Trung (external author)
  •   Lam, Alfred (external author)
  •   Hossain, Md Shahriar
  •   Yamauchi, Yusuke (external author)
  •   Shiddiky, Muhammad J. A. (external author)

Publication Date

  • 2017

Citation

  • Masud, M. Kamal., Islam, M., Haque, M. Hakimul., Tanaka, S., Gopalan, V., Alici, G., Nguyen, N., Lam, A. K., Hossain, M. Al., Yamauchi, Y. & Shiddiky, M. J. A. (2017). Gold-loaded nanoporous superparamagnetic nanocubes for catalytic signal amplification in detecting miRNA. Chemical Communications, 53 (58), 8231-8234.

Scopus Eid

  • 2-s2.0-85024892976

Ro Metadata Url

  • http://ro.uow.edu.au/aiimpapers/2630

Number Of Pages

  • 3

Start Page

  • 8231

End Page

  • 8234

Volume

  • 53

Issue

  • 58

Place Of Publication

  • United Kingdom

Abstract

  • This paper reports the development of a nonenzymatic, amplificationfree,

    and sensitive platform for the detection of microRNA based on a

    new class of electrocatalytically active superparamagnetic gold-loaded

    nanoporous iron oxide nanocubes (Au@NPFe2O3NC). The assay showed

    an excellent detection sensitivity down to 100 fM and specificity towards

    the analysis of miR-21 in cell lines and tissue samples derived from

    patients with oesophageal squamous-cell carcinoma (ESCC).

UOW Authors

  •   Masud, Mostafa (external author)
  •   Islam, Md Nazmul (external author)
  •   Haque, Md Hakimul. (external author)
  •   Tanaka, Shunsuke (external author)
  •   Gopalan, Vinod (external author)
  •   Alici, Gursel
  •   Nguyen, Nam-Trung (external author)
  •   Lam, Alfred (external author)
  •   Hossain, Md Shahriar
  •   Yamauchi, Yusuke (external author)
  •   Shiddiky, Muhammad J. A. (external author)

Publication Date

  • 2017

Citation

  • Masud, M. Kamal., Islam, M., Haque, M. Hakimul., Tanaka, S., Gopalan, V., Alici, G., Nguyen, N., Lam, A. K., Hossain, M. Al., Yamauchi, Y. & Shiddiky, M. J. A. (2017). Gold-loaded nanoporous superparamagnetic nanocubes for catalytic signal amplification in detecting miRNA. Chemical Communications, 53 (58), 8231-8234.

Scopus Eid

  • 2-s2.0-85024892976

Ro Metadata Url

  • http://ro.uow.edu.au/aiimpapers/2630

Number Of Pages

  • 3

Start Page

  • 8231

End Page

  • 8234

Volume

  • 53

Issue

  • 58

Place Of Publication

  • United Kingdom