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Negative Pressure Induced Droplet Generation in a Microfluidic Flow-Focusing Device

Journal Article


Abstract


  • We introduce an effective method to actively induce droplet generation using negative pressure. Droplets can be generated on demand using a series of periodic negative pressure pulses. Fluidic network models were developed using the analogy to electric networks to relate the pressure conditions for different flow regimes. Experimental results show that the droplet volume is correlated to the pressure ratio with a power law of 1.3. Using a pulsed negative pressure at the outlet, we are able to produce droplets in demand and with a volume proportional to the pulse width.

UOW Authors


  •   Teo, Adrian (external author)
  •   Li, King-Ho Holden (external author)
  •   Nguyen, Nam-Trung (external author)
  •   Guo, Wei (external author)
  •   Heere, Nadine (external author)
  •   Xi, Heng (external author)
  •   Tsao, Chia (external author)
  •   Li, Weihua
  •   Tan, Say H. (external author)

Publication Date


  • 2017

Citation


  • Teo, A. J. T., Li, K., Nguyen, N., Guo, W., Heere, N., Xi, H., Tsao, C., Li, W. & Tan, S. H. (2017). Negative Pressure Induced Droplet Generation in a Microfluidic Flow-Focusing Device. Analytical Chemistry, 89 (8), 4387-4391.

Scopus Eid


  • 2-s2.0-85019985542

Number Of Pages


  • 4

Start Page


  • 4387

End Page


  • 4391

Volume


  • 89

Issue


  • 8

Place Of Publication


  • United States

Abstract


  • We introduce an effective method to actively induce droplet generation using negative pressure. Droplets can be generated on demand using a series of periodic negative pressure pulses. Fluidic network models were developed using the analogy to electric networks to relate the pressure conditions for different flow regimes. Experimental results show that the droplet volume is correlated to the pressure ratio with a power law of 1.3. Using a pulsed negative pressure at the outlet, we are able to produce droplets in demand and with a volume proportional to the pulse width.

UOW Authors


  •   Teo, Adrian (external author)
  •   Li, King-Ho Holden (external author)
  •   Nguyen, Nam-Trung (external author)
  •   Guo, Wei (external author)
  •   Heere, Nadine (external author)
  •   Xi, Heng (external author)
  •   Tsao, Chia (external author)
  •   Li, Weihua
  •   Tan, Say H. (external author)

Publication Date


  • 2017

Citation


  • Teo, A. J. T., Li, K., Nguyen, N., Guo, W., Heere, N., Xi, H., Tsao, C., Li, W. & Tan, S. H. (2017). Negative Pressure Induced Droplet Generation in a Microfluidic Flow-Focusing Device. Analytical Chemistry, 89 (8), 4387-4391.

Scopus Eid


  • 2-s2.0-85019985542

Number Of Pages


  • 4

Start Page


  • 4387

End Page


  • 4391

Volume


  • 89

Issue


  • 8

Place Of Publication


  • United States