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P2X7 receptor antagonism in amyotrophic lateral sclerosis

Journal Article


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Abstract


  • Amyotrophic lateral sclerosis (ALS) is a rapidly progressive disorder characterized by the degeneration and subsequent loss of upper and lower motor neurons, resulting in reduced muscle

    function and paralysis (Mathis et al., 2017). Current therapies are limited to the oral administration of riluzole, which improves survival by only 3 months (Mathis et al., 2017). Thus, new therapies are urgently required to treat this neurodegenerative disorder.

Publication Date


  • 2017

Citation


  • Sluyter, R., Bartlett, R., Ly, D. & Yerbury, J. J. (2017). P2X7 receptor antagonism in amyotrophic lateral sclerosis. Neural Regeneration Research, 12 (5), 749-750.

Scopus Eid


  • 2-s2.0-85020764223

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=2098&context=ihmri

Ro Metadata Url


  • http://ro.uow.edu.au/ihmri/1072

Has Global Citation Frequency


Number Of Pages


  • 1

Start Page


  • 749

End Page


  • 750

Volume


  • 12

Issue


  • 5

Place Of Publication


  • India

Abstract


  • Amyotrophic lateral sclerosis (ALS) is a rapidly progressive disorder characterized by the degeneration and subsequent loss of upper and lower motor neurons, resulting in reduced muscle

    function and paralysis (Mathis et al., 2017). Current therapies are limited to the oral administration of riluzole, which improves survival by only 3 months (Mathis et al., 2017). Thus, new therapies are urgently required to treat this neurodegenerative disorder.

Publication Date


  • 2017

Citation


  • Sluyter, R., Bartlett, R., Ly, D. & Yerbury, J. J. (2017). P2X7 receptor antagonism in amyotrophic lateral sclerosis. Neural Regeneration Research, 12 (5), 749-750.

Scopus Eid


  • 2-s2.0-85020764223

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=2098&context=ihmri

Ro Metadata Url


  • http://ro.uow.edu.au/ihmri/1072

Has Global Citation Frequency


Number Of Pages


  • 1

Start Page


  • 749

End Page


  • 750

Volume


  • 12

Issue


  • 5

Place Of Publication


  • India