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Neandertal and Denisovan DNA from Pleistocene sediments

Journal Article


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Abstract


  • Although a rich record of Pleistocene human-associated archaeological assemblages exists, the scarcity of hominin fossils often impedes the understanding of which hominins occupied a site. Using targeted enrichment of mitochondrial DNA, we show that cave sediments represent a rich source of ancient mammalian DNA that often includes traces of hominin DNA, even at sites and in layers where no hominin remains have been discovered. By automation-assisted screening of numerous sediment samples, we detected Neandertal DNA in eight archaeological layers from four caves in Eurasia. In Denisova Cave, we retrieved Denisovan DNA in a Middle Pleistocene layer near the bottom of the stratigraphy. Our work opens the possibility of detecting the presence of hominin groups at sites and in areas where no skeletal remains are found.

Authors


  •   Slon, Viviane (external author)
  •   Hopfe, Charlotte (external author)
  •   Weiß, Clemens (external author)
  •   Mafessoni, Fabrizio (external author)
  •   de la Rasilla, Marco (external author)
  •   Lalueza-Fox, Carles (external author)
  •   Rosas, Antonio (external author)
  •   Soressi, Marie (external author)
  •   Knul, Monika (external author)
  •   Miller, Rebecca (external author)
  •   Jacobs, Zenobia
  •   Li, Bo
  •   Roberts, Richard G.

Publication Date


  • 2017

Citation


  • Slon, V., Hopfe, C., Weiß, C. L., Mafessoni, F., de la Rasilla, M., Lalueza-Fox, C., Rosas, A., Soressi, M., Knul, M. V., Miller, R., Jacobs, Z., Li, B., Roberts, R. G. et al (2017). Neandertal and Denisovan DNA from Pleistocene sediments. Science, 356 (6338), 605-608.

Scopus Eid


  • 2-s2.0-85018442438

Ro Full-text Url


  • https://ro.uow.edu.au/cgi/viewcontent.cgi?article=5679&context=smhpapers

Ro Metadata Url


  • http://ro.uow.edu.au/smhpapers/4653

Has Global Citation Frequency


Number Of Pages


  • 3

Start Page


  • 605

End Page


  • 608

Volume


  • 356

Issue


  • 6338

Place Of Publication


  • United States

Abstract


  • Although a rich record of Pleistocene human-associated archaeological assemblages exists, the scarcity of hominin fossils often impedes the understanding of which hominins occupied a site. Using targeted enrichment of mitochondrial DNA, we show that cave sediments represent a rich source of ancient mammalian DNA that often includes traces of hominin DNA, even at sites and in layers where no hominin remains have been discovered. By automation-assisted screening of numerous sediment samples, we detected Neandertal DNA in eight archaeological layers from four caves in Eurasia. In Denisova Cave, we retrieved Denisovan DNA in a Middle Pleistocene layer near the bottom of the stratigraphy. Our work opens the possibility of detecting the presence of hominin groups at sites and in areas where no skeletal remains are found.

Authors


  •   Slon, Viviane (external author)
  •   Hopfe, Charlotte (external author)
  •   Weiß, Clemens (external author)
  •   Mafessoni, Fabrizio (external author)
  •   de la Rasilla, Marco (external author)
  •   Lalueza-Fox, Carles (external author)
  •   Rosas, Antonio (external author)
  •   Soressi, Marie (external author)
  •   Knul, Monika (external author)
  •   Miller, Rebecca (external author)
  •   Jacobs, Zenobia
  •   Li, Bo
  •   Roberts, Richard G.

Publication Date


  • 2017

Citation


  • Slon, V., Hopfe, C., Weiß, C. L., Mafessoni, F., de la Rasilla, M., Lalueza-Fox, C., Rosas, A., Soressi, M., Knul, M. V., Miller, R., Jacobs, Z., Li, B., Roberts, R. G. et al (2017). Neandertal and Denisovan DNA from Pleistocene sediments. Science, 356 (6338), 605-608.

Scopus Eid


  • 2-s2.0-85018442438

Ro Full-text Url


  • https://ro.uow.edu.au/cgi/viewcontent.cgi?article=5679&context=smhpapers

Ro Metadata Url


  • http://ro.uow.edu.au/smhpapers/4653

Has Global Citation Frequency


Number Of Pages


  • 3

Start Page


  • 605

End Page


  • 608

Volume


  • 356

Issue


  • 6338

Place Of Publication


  • United States