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Seed mediated one-pot growth of versatile heterogeneous upconversion nanocrystals for multimodal bioimaging

Journal Article


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Abstract


  • The rapid development of a variety of molecular contrast agents makes the multimodality bioimaging highly attractive

    towards higher resolution, more sensitive, informative diagnosis. The key lies in the development of facile material

    synthesis that allows the integration of multiple contrast agents, ideally in a way that each of the components should

    be logically assembled to maximize their performances. Here, we report the one-pot programmable growth of

    multifunctional heterogeneous nanocrystal with tunable size, shape, composition, and properties. We demonstrated a

    facile one-pot hot-injection method to enable the highly selectively controlled growth of different sodium lanthanide

    fluoride nanomaterials in either longitudinal or transversal directions with atomic scale precision. This technique

    allows the upconversion luminescence signal, MRI signal and x-ray signal logically integrated and optimized within

    one single versatile nanoplatform for multimode bioimaging. These findings suggest that the facile strategy developed

    here have the promising to get the desired heterogeneous nanocrystals as an all-in-one contrast agent for integrated

    and self-correlative multimodal bioimaging.

UOW Authors


  •   Wen, Shihui (external author)
  •   Li, Du (external author)
  •   Liu, Deming (external author)
  •   Xu, Xiaoxue (external author)
  •   Du, Yi
  •   Mitchell, David
  •   Shi, Bingyang (external author)
  •   Shi, Xiangyang (external author)
  •   Jin, Dayong (external author)

Publication Date


  • 2016

Citation


  • Wen, S., Li, D., Liu, D., Xu, X., Du, Y., Mitchell, D. R. G., Shi, B., Shi, X. & Jin, D. (2016). Seed mediated one-pot growth of versatile heterogeneous upconversion nanocrystals for multimodal bioimaging. SPIE - International Society for Optical Engineering. Proceedings, 10013 1001315-1-1001315-7.

Scopus Eid


  • 2-s2.0-85011397494

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=3362&context=aiimpapers

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/2339

Start Page


  • 1001315-1

End Page


  • 1001315-7

Volume


  • 10013

Place Of Publication


  • United States

Abstract


  • The rapid development of a variety of molecular contrast agents makes the multimodality bioimaging highly attractive

    towards higher resolution, more sensitive, informative diagnosis. The key lies in the development of facile material

    synthesis that allows the integration of multiple contrast agents, ideally in a way that each of the components should

    be logically assembled to maximize their performances. Here, we report the one-pot programmable growth of

    multifunctional heterogeneous nanocrystal with tunable size, shape, composition, and properties. We demonstrated a

    facile one-pot hot-injection method to enable the highly selectively controlled growth of different sodium lanthanide

    fluoride nanomaterials in either longitudinal or transversal directions with atomic scale precision. This technique

    allows the upconversion luminescence signal, MRI signal and x-ray signal logically integrated and optimized within

    one single versatile nanoplatform for multimode bioimaging. These findings suggest that the facile strategy developed

    here have the promising to get the desired heterogeneous nanocrystals as an all-in-one contrast agent for integrated

    and self-correlative multimodal bioimaging.

UOW Authors


  •   Wen, Shihui (external author)
  •   Li, Du (external author)
  •   Liu, Deming (external author)
  •   Xu, Xiaoxue (external author)
  •   Du, Yi
  •   Mitchell, David
  •   Shi, Bingyang (external author)
  •   Shi, Xiangyang (external author)
  •   Jin, Dayong (external author)

Publication Date


  • 2016

Citation


  • Wen, S., Li, D., Liu, D., Xu, X., Du, Y., Mitchell, D. R. G., Shi, B., Shi, X. & Jin, D. (2016). Seed mediated one-pot growth of versatile heterogeneous upconversion nanocrystals for multimodal bioimaging. SPIE - International Society for Optical Engineering. Proceedings, 10013 1001315-1-1001315-7.

Scopus Eid


  • 2-s2.0-85011397494

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=3362&context=aiimpapers

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/2339

Start Page


  • 1001315-1

End Page


  • 1001315-7

Volume


  • 10013

Place Of Publication


  • United States