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Investigation of particle lateral migration in sample-sheath flow of viscoelastic fluid and Newtonian fluid

Journal Article


Abstract


  • In this work, particle lateral migration in sample-sheath flow of viscoelastic fluid and Newtonian fluid was experimentally investigated. The 4.8-μm micro-particles were dispersed in a polyethylene oxide (PEO) viscoelastic solution, and then the solution was injected into a straight rectangular channel with a deionised (DI) water Newtonian sheath flow. Micro-particles suspended in PEO solution migrated laterally to a DI water stream, but migration in the opposite direction from a DI water stream to a PEO solution stream or from one DI water stream to another DI water stream could not be achieved. The lateral migration of particles depends on the viscoelastic properties of the sample fluids. Furthermore, the effects of channel length, flow rate, and PEO concentration were studied. By using viscoelastic sample flow and Newtonian sheath flow, a selective particle lateral migration can be achieved in a simple straight channel, without any external force fields. This particle lateral migration technique could be potentially used in solution exchange fields such as automated cell staining and washing in microfluidic platforms, and holds numerous biomedical applications.

Authors


  •   Yuan, Dan (external author)
  •   Zhang, Jun (external author)
  •   Yan, Sheng (external author)
  •   Peng, Gangrou (external author)
  •   Zhao, Qianbin (external author)
  •   Alici, Gursel
  •   Du, Hejun (external author)
  •   Li, Weihua

Publication Date


  • 2016

Citation


  • Yuan, D., Zhang, J., Yan, S., Peng, G., Zhao, Q., Alici, G., Du, H. & Li, W. (2016). Investigation of particle lateral migration in sample-sheath flow of viscoelastic fluid and Newtonian fluid. Electrophoresis, 37 (15-16), 2147-2155.

Scopus Eid


  • 2-s2.0-84981747481

Ro Metadata Url


  • http://ro.uow.edu.au/eispapers/5911

Has Global Citation Frequency


Number Of Pages


  • 8

Start Page


  • 2147

End Page


  • 2155

Volume


  • 37

Issue


  • 15-16

Place Of Publication


  • Germany

Abstract


  • In this work, particle lateral migration in sample-sheath flow of viscoelastic fluid and Newtonian fluid was experimentally investigated. The 4.8-μm micro-particles were dispersed in a polyethylene oxide (PEO) viscoelastic solution, and then the solution was injected into a straight rectangular channel with a deionised (DI) water Newtonian sheath flow. Micro-particles suspended in PEO solution migrated laterally to a DI water stream, but migration in the opposite direction from a DI water stream to a PEO solution stream or from one DI water stream to another DI water stream could not be achieved. The lateral migration of particles depends on the viscoelastic properties of the sample fluids. Furthermore, the effects of channel length, flow rate, and PEO concentration were studied. By using viscoelastic sample flow and Newtonian sheath flow, a selective particle lateral migration can be achieved in a simple straight channel, without any external force fields. This particle lateral migration technique could be potentially used in solution exchange fields such as automated cell staining and washing in microfluidic platforms, and holds numerous biomedical applications.

Authors


  •   Yuan, Dan (external author)
  •   Zhang, Jun (external author)
  •   Yan, Sheng (external author)
  •   Peng, Gangrou (external author)
  •   Zhao, Qianbin (external author)
  •   Alici, Gursel
  •   Du, Hejun (external author)
  •   Li, Weihua

Publication Date


  • 2016

Citation


  • Yuan, D., Zhang, J., Yan, S., Peng, G., Zhao, Q., Alici, G., Du, H. & Li, W. (2016). Investigation of particle lateral migration in sample-sheath flow of viscoelastic fluid and Newtonian fluid. Electrophoresis, 37 (15-16), 2147-2155.

Scopus Eid


  • 2-s2.0-84981747481

Ro Metadata Url


  • http://ro.uow.edu.au/eispapers/5911

Has Global Citation Frequency


Number Of Pages


  • 8

Start Page


  • 2147

End Page


  • 2155

Volume


  • 37

Issue


  • 15-16

Place Of Publication


  • Germany