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Highly enantioselective reaction of 2-oxindoles with (3-indolyl)methanols by cooperative Catalysis of a Lewis acid and organocatalyst

Journal Article


Abstract


  • An efficient cooperative biscinchona alkaloid and Lewis acid catalytic system was developed in the enantioselective α-alkylation of 2-oxindoles with (3-indolyl)(phenyl)methanols to provide (2-oxindole)-linker-indole derivatives in good yields (70-83%) with high enantioselectivities (81%-92%).

Authors


  •   Ren, Chhuan-Li (external author)
  •   Zhang, Tao (external author)
  •   Wang, Xingyong
  •   Wu, Tao (external author)
  •   Ma, Jing (external author)
  •   Xuan, Qing-Qing (external author)
  •   Wei, Feng (external author)
  •   Huang, Hong-Yan (external author)
  •   Wang, Dong (external author)
  •   Liu, Li (external author)

Publication Date


  • 2014

Geographic Focus


Citation


  • Ren, C., Zhang, T., Wang, X., Wu, T., Ma, J., Xuan, Q., Wei, F., Huang, H., Wang, D. & Liu, L. (2014). Highly enantioselective reaction of 2-oxindoles with (3-indolyl)methanols by cooperative Catalysis of a Lewis acid and organocatalyst. Organic and Biomolecular Chemistry, 12 (48), 9881-9886.

Scopus Eid


  • 2-s2.0-84911883535

Ro Metadata Url


  • http://ro.uow.edu.au/smhpapers/3919

Has Global Citation Frequency


Number Of Pages


  • 5

Start Page


  • 9881

End Page


  • 9886

Volume


  • 12

Issue


  • 48

Place Of Publication


  • United Kingdom

Abstract


  • An efficient cooperative biscinchona alkaloid and Lewis acid catalytic system was developed in the enantioselective α-alkylation of 2-oxindoles with (3-indolyl)(phenyl)methanols to provide (2-oxindole)-linker-indole derivatives in good yields (70-83%) with high enantioselectivities (81%-92%).

Authors


  •   Ren, Chhuan-Li (external author)
  •   Zhang, Tao (external author)
  •   Wang, Xingyong
  •   Wu, Tao (external author)
  •   Ma, Jing (external author)
  •   Xuan, Qing-Qing (external author)
  •   Wei, Feng (external author)
  •   Huang, Hong-Yan (external author)
  •   Wang, Dong (external author)
  •   Liu, Li (external author)

Publication Date


  • 2014

Geographic Focus


Citation


  • Ren, C., Zhang, T., Wang, X., Wu, T., Ma, J., Xuan, Q., Wei, F., Huang, H., Wang, D. & Liu, L. (2014). Highly enantioselective reaction of 2-oxindoles with (3-indolyl)methanols by cooperative Catalysis of a Lewis acid and organocatalyst. Organic and Biomolecular Chemistry, 12 (48), 9881-9886.

Scopus Eid


  • 2-s2.0-84911883535

Ro Metadata Url


  • http://ro.uow.edu.au/smhpapers/3919

Has Global Citation Frequency


Number Of Pages


  • 5

Start Page


  • 9881

End Page


  • 9886

Volume


  • 12

Issue


  • 48

Place Of Publication


  • United Kingdom