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A rapid and reliable technique for N-nitrosodimethylamine analysis in reclaimed water by HPLC-photochemical reaction-chemiluminescence

Journal Article


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Abstract


  • A fast and reliable analytical technique was evaluated and validated for determination of N-nitrosodimethylamine

    (NDMA) formation and rejection by reverse osmosis (RO) membranes in potable water

    reuse applications. The analytical instrument used in this study is high-performance liquid chromatography

    (HPLC), photochemical reaction (PR) and chemiluminescence (CL) e namely HPLC-PR-CL. Results

    reported here show that HPLC-PR-CL can be used to measure NDMA with a similar level of accuracy

    compared to conventional and more time-consuming techniques using gas chromatography and tandem

    mass spectrometry detection in combination with solid phase extraction. Among key residual chemicals

    (i.e. monochloramine, hydrogen peroxide and hypochlorite) in reclaimed wastewater, hypochlorite was

    the only constituent that interfered with the determination of NDMA by HPLC-PR-CL. However, hypochlorite

    interference was eliminated by adding ascorbic acid as a reducing agent. Direct injection of

    ultrafiltration (UF)-treated wastewater samples into HPLC-PR-CL also resulted in an underestimation of

    the NDMA concentration possibly due to interference by organic substances in the UF-treated wastewater.

    Accurate determination of NDMA concentrations in UF-treated wastewater was achieved by

    reducing the sample injection volume from 200 to 20 mL, though this increased the method detection

    limit from 0.2 to 2 ng/L. In contrast, no interference was observed with RO permeate. These results

    suggest that RO membranes could remove part of substances that interfere with the NDMA analysis by

Authors


  •   Fujioka, Takahiro (external author)
  •   Takeuchi, Haruka (external author)
  •   Tanaka, Hiroaki (external author)
  •   Nghiem, Long D.
  •   Ishida, Kenneth P. (external author)
  •   Kodamatani, Hitoshi (external author)

Publication Date


  • 2016

Citation


  • Fujioka, T., Takeuchi, H., Tanaka, H., Nghiem, L. D., Ishida, K. P. & Kodamatani, H. (2016). A rapid and reliable technique for N-nitrosodimethylamine analysis in reclaimed water by HPLC-photochemical reaction-chemiluminescence. Chemosphere, 161 104-111.

Scopus Eid


  • 2-s2.0-84978296445

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=6717&context=eispapers

Ro Metadata Url


  • http://ro.uow.edu.au/eispapers/5689

Has Global Citation Frequency


Number Of Pages


  • 7

Start Page


  • 104

End Page


  • 111

Volume


  • 161

Place Of Publication


  • United Kingdom

Abstract


  • A fast and reliable analytical technique was evaluated and validated for determination of N-nitrosodimethylamine

    (NDMA) formation and rejection by reverse osmosis (RO) membranes in potable water

    reuse applications. The analytical instrument used in this study is high-performance liquid chromatography

    (HPLC), photochemical reaction (PR) and chemiluminescence (CL) e namely HPLC-PR-CL. Results

    reported here show that HPLC-PR-CL can be used to measure NDMA with a similar level of accuracy

    compared to conventional and more time-consuming techniques using gas chromatography and tandem

    mass spectrometry detection in combination with solid phase extraction. Among key residual chemicals

    (i.e. monochloramine, hydrogen peroxide and hypochlorite) in reclaimed wastewater, hypochlorite was

    the only constituent that interfered with the determination of NDMA by HPLC-PR-CL. However, hypochlorite

    interference was eliminated by adding ascorbic acid as a reducing agent. Direct injection of

    ultrafiltration (UF)-treated wastewater samples into HPLC-PR-CL also resulted in an underestimation of

    the NDMA concentration possibly due to interference by organic substances in the UF-treated wastewater.

    Accurate determination of NDMA concentrations in UF-treated wastewater was achieved by

    reducing the sample injection volume from 200 to 20 mL, though this increased the method detection

    limit from 0.2 to 2 ng/L. In contrast, no interference was observed with RO permeate. These results

    suggest that RO membranes could remove part of substances that interfere with the NDMA analysis by

Authors


  •   Fujioka, Takahiro (external author)
  •   Takeuchi, Haruka (external author)
  •   Tanaka, Hiroaki (external author)
  •   Nghiem, Long D.
  •   Ishida, Kenneth P. (external author)
  •   Kodamatani, Hitoshi (external author)

Publication Date


  • 2016

Citation


  • Fujioka, T., Takeuchi, H., Tanaka, H., Nghiem, L. D., Ishida, K. P. & Kodamatani, H. (2016). A rapid and reliable technique for N-nitrosodimethylamine analysis in reclaimed water by HPLC-photochemical reaction-chemiluminescence. Chemosphere, 161 104-111.

Scopus Eid


  • 2-s2.0-84978296445

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=6717&context=eispapers

Ro Metadata Url


  • http://ro.uow.edu.au/eispapers/5689

Has Global Citation Frequency


Number Of Pages


  • 7

Start Page


  • 104

End Page


  • 111

Volume


  • 161

Place Of Publication


  • United Kingdom