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People with schizophrenia and depression have a low omega-3 index

Journal Article


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Abstract


  • Cardiovascular disease (CVD) is higher in people with mental illness and is associated with a 30 year higher mortality rate in this population. Erythrocyte docosahexaenoic acid (DHA) plus eicosapentaenoic acid (EPA) (omega-3 index)≤4% is a marker for increased mortality risk from CVD while >8% is protective. Omega-3 polyunsaturated fatty acids are also important for brain function and may ameliorate symptoms of mental illness. We investigated the erythrocyte omega-3 index in people with mental illness. One hundred and thirty adults aged 18–65 years (32.6% male) with schizophrenia (n=14) and depression (n=116) provided blood samples and completed physiological assessments and questionnaires. Both populations had risk factors for metabolic syndrome and CVD. The average omega-3 index was 3.95% (SD=1.06), compared to an estimated 5% in the Australian population. These data indicate an unfavourable omega-3 profile in people with mental illness that could contribute to higher CVD risk.

Authors


  •   Parletta, Natalie (external author)
  •   Zarnowiecki, Dorota M. (external author)
  •   Cho, Jihyun (external author)
  •   Wilson, Amy (external author)
  •   Procter, Nicholas (external author)
  •   Gordon, Andrea (external author)
  •   Bogomolova, Svetlana (external author)
  •   O'Dea, Kerin (external author)
  •   Strachan, John (external author)
  •   Ballestrin, Matt (external author)
  •   Champion, Andrew (external author)
  •   Meyer, Barbara J.

Publication Date


  • 2016

Citation


  • Parletta, N., Zarnowiecki, D., Cho, J., Wilson, A., Procter, N., Gordon, A., Bogomolova, S., O'Dea, K., Strachan, J., Ballestrin, M., Champion, A. & Meyer, B. J. (2016). People with schizophrenia and depression have a low omega-3 index. Prostaglandins, Leukotrienes and Essential Fatty Acids, 110 42-47.

Scopus Eid


  • 2-s2.0-84969972553

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=4842&context=smhpapers

Ro Metadata Url


  • http://ro.uow.edu.au/smhpapers/3819

Has Global Citation Frequency


Number Of Pages


  • 5

Start Page


  • 42

End Page


  • 47

Volume


  • 110

Place Of Publication


  • United Kingdom

Abstract


  • Cardiovascular disease (CVD) is higher in people with mental illness and is associated with a 30 year higher mortality rate in this population. Erythrocyte docosahexaenoic acid (DHA) plus eicosapentaenoic acid (EPA) (omega-3 index)≤4% is a marker for increased mortality risk from CVD while >8% is protective. Omega-3 polyunsaturated fatty acids are also important for brain function and may ameliorate symptoms of mental illness. We investigated the erythrocyte omega-3 index in people with mental illness. One hundred and thirty adults aged 18–65 years (32.6% male) with schizophrenia (n=14) and depression (n=116) provided blood samples and completed physiological assessments and questionnaires. Both populations had risk factors for metabolic syndrome and CVD. The average omega-3 index was 3.95% (SD=1.06), compared to an estimated 5% in the Australian population. These data indicate an unfavourable omega-3 profile in people with mental illness that could contribute to higher CVD risk.

Authors


  •   Parletta, Natalie (external author)
  •   Zarnowiecki, Dorota M. (external author)
  •   Cho, Jihyun (external author)
  •   Wilson, Amy (external author)
  •   Procter, Nicholas (external author)
  •   Gordon, Andrea (external author)
  •   Bogomolova, Svetlana (external author)
  •   O'Dea, Kerin (external author)
  •   Strachan, John (external author)
  •   Ballestrin, Matt (external author)
  •   Champion, Andrew (external author)
  •   Meyer, Barbara J.

Publication Date


  • 2016

Citation


  • Parletta, N., Zarnowiecki, D., Cho, J., Wilson, A., Procter, N., Gordon, A., Bogomolova, S., O'Dea, K., Strachan, J., Ballestrin, M., Champion, A. & Meyer, B. J. (2016). People with schizophrenia and depression have a low omega-3 index. Prostaglandins, Leukotrienes and Essential Fatty Acids, 110 42-47.

Scopus Eid


  • 2-s2.0-84969972553

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=4842&context=smhpapers

Ro Metadata Url


  • http://ro.uow.edu.au/smhpapers/3819

Has Global Citation Frequency


Number Of Pages


  • 5

Start Page


  • 42

End Page


  • 47

Volume


  • 110

Place Of Publication


  • United Kingdom