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Detection of familial hypercholesterolaemia: a major treatment gap in preventative cardiology

Journal Article


Abstract


  • Familial hypercholesterolaemia (FH) is a common genetic disorder that untreated has an almost one hundredfold risk of coronary artery disease (CAD). In an audit of 334 patients with premature CAD admitted to a Department of Cardiology, only 60% of medical records had sufficient clinical information for identifying FH. Of those with sufficient information recorded, 54% of patients had possible to definite FH on recognised clinical criteria. Amongst those with FH, only 38% were on statin therapy and only 22% were treated to National Heart Foundation targets. Detection and treatment of FH represents a major gap in coronary prevention.

Authors


  •   Bates, Timothy R. (external author)
  •   Burnett, John R. (external author)
  •   Van Bockxmeer, Frank M. (external author)
  •   Hamilton, Sandra (external author)
  •   Arnolda, Leonard F.
  •   Watts, Gerald F. (external author)

Publication Date


  • 2008

Citation


  • Bates, T. R., Burnett, J. R., van Bockxmeer, F. M., Hamilton, S., Arnolda, L. & Watts, G. F. (2008). Detection of familial hypercholesterolaemia: a major treatment gap in preventative cardiology. Heart Lung and Circulation, 17 (5), 411-413.

Scopus Eid


  • 2-s2.0-50249097669

Ro Metadata Url


  • http://ro.uow.edu.au/ihmri/800

Has Global Citation Frequency


Number Of Pages


  • 2

Start Page


  • 411

End Page


  • 413

Volume


  • 17

Issue


  • 5

Place Of Publication


  • Australia

Abstract


  • Familial hypercholesterolaemia (FH) is a common genetic disorder that untreated has an almost one hundredfold risk of coronary artery disease (CAD). In an audit of 334 patients with premature CAD admitted to a Department of Cardiology, only 60% of medical records had sufficient clinical information for identifying FH. Of those with sufficient information recorded, 54% of patients had possible to definite FH on recognised clinical criteria. Amongst those with FH, only 38% were on statin therapy and only 22% were treated to National Heart Foundation targets. Detection and treatment of FH represents a major gap in coronary prevention.

Authors


  •   Bates, Timothy R. (external author)
  •   Burnett, John R. (external author)
  •   Van Bockxmeer, Frank M. (external author)
  •   Hamilton, Sandra (external author)
  •   Arnolda, Leonard F.
  •   Watts, Gerald F. (external author)

Publication Date


  • 2008

Citation


  • Bates, T. R., Burnett, J. R., van Bockxmeer, F. M., Hamilton, S., Arnolda, L. & Watts, G. F. (2008). Detection of familial hypercholesterolaemia: a major treatment gap in preventative cardiology. Heart Lung and Circulation, 17 (5), 411-413.

Scopus Eid


  • 2-s2.0-50249097669

Ro Metadata Url


  • http://ro.uow.edu.au/ihmri/800

Has Global Citation Frequency


Number Of Pages


  • 2

Start Page


  • 411

End Page


  • 413

Volume


  • 17

Issue


  • 5

Place Of Publication


  • Australia