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Brain on a bench top

Journal Article


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Abstract


  • Tissue grafting and organ transplantation are common techniques

    in modern medicine, but suffer from the widely-reported

    limitations of constrained supply and the risk of rejection, necessitating

    a lifetime of immunosuppressant medication [1]. The field

    of tissue engineering has advanced markedly over the last decade,

    and engineered tissues are under development for both regenerative

    medicine applications as well as the formation of accurate in

    vitro models for the study of fundamental tissue behaviours, disease

    states and drug discovery. Both biological and synthetic

    materials have been formed into cell-supporting tissue scaffolds

    [2,3]. In broad terms, biological materials and particularly extracellular

    matrix (ECM) components offer superior cell interaction

    properties, but are challenging to process [4]. Synthetic materials

    are readily processed, but may lack specific or necessary cell

    interaction motifs. The fabrication of truly biomimetic regenerative

    scaffolds is an incredibly complex challenge, one that requires

    an integrated approach to both biomaterials and biofabrication

    technologies [5].

Publication Date


  • 2016

Citation


  • Lozano, R., Stevens, L., Thompson, B. C., Gilmore, K. J., Gorkin III, R., Stewart, E. M., in het Panhuis, M., Romero-Ortega, M. & Wallace, G. G. (2016). Brain on a bench top. Materials Today, 19 (2), 124-125.

Scopus Eid


  • 2-s2.0-84959553449

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=3081&context=aiimpapers

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/2079

Number Of Pages


  • 1

Start Page


  • 124

End Page


  • 125

Volume


  • 19

Issue


  • 2

Place Of Publication


  • Netherlands

Abstract


  • Tissue grafting and organ transplantation are common techniques

    in modern medicine, but suffer from the widely-reported

    limitations of constrained supply and the risk of rejection, necessitating

    a lifetime of immunosuppressant medication [1]. The field

    of tissue engineering has advanced markedly over the last decade,

    and engineered tissues are under development for both regenerative

    medicine applications as well as the formation of accurate in

    vitro models for the study of fundamental tissue behaviours, disease

    states and drug discovery. Both biological and synthetic

    materials have been formed into cell-supporting tissue scaffolds

    [2,3]. In broad terms, biological materials and particularly extracellular

    matrix (ECM) components offer superior cell interaction

    properties, but are challenging to process [4]. Synthetic materials

    are readily processed, but may lack specific or necessary cell

    interaction motifs. The fabrication of truly biomimetic regenerative

    scaffolds is an incredibly complex challenge, one that requires

    an integrated approach to both biomaterials and biofabrication

    technologies [5].

Publication Date


  • 2016

Citation


  • Lozano, R., Stevens, L., Thompson, B. C., Gilmore, K. J., Gorkin III, R., Stewart, E. M., in het Panhuis, M., Romero-Ortega, M. & Wallace, G. G. (2016). Brain on a bench top. Materials Today, 19 (2), 124-125.

Scopus Eid


  • 2-s2.0-84959553449

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=3081&context=aiimpapers

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/2079

Number Of Pages


  • 1

Start Page


  • 124

End Page


  • 125

Volume


  • 19

Issue


  • 2

Place Of Publication


  • Netherlands