This study explores the links between human resource (HR) practices, presenteeism and employee turnover intentions. In particular, we investigate the mediating effect of employee turnover intentions on the relationship between HR practices and presenteeism. Hypotheses were tested using responses from a web-based survey of 200 full-time Australian employees. The results show that HR practices significantly influence presenteeism and employee turnover intentions. As predicted, both HR practices and employee turnover intentions were significantly associated with presenteeism in negative and positive effects respectively. The direct relationship between HR practices and presenteeism was fully mediated by employees’ turnover intentions. The results suggest that organizations hoping to use HR practices to discourage presenteeism may experience an adverse result if the employees conceal turnover intentions.