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Preimplantation exposure to Bisphenol A and Triclosan may lead to implantation failure in humans

Journal Article


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Abstract


  • Endocrine disrupting chemicals (EDCs) are chemicals that have the capacity to interfere with normal endocrine systems. Two

    EDCs, bisphenol A (BPA) and triclosan (TCS), are mass-produced and are widespread.They both have estrogenic properties and

    similar chemical structures and pharmacokinetic features and have been detected in human fluids and tissues. Clinical evidence

    has suggested a positive association between BPA exposure and implantation failure in IVF patients. Studies inmouse models have

    suggested that preimplantation exposure to BPA and TCS can lead to implantation failure. This paper reviews the relationship

    between preimplantation exposure to BPA and TCS and implantation failure and discusses the remaining problems and possible

    solutions.

Authors


  •   Yuan, Mu (external author)
  •   Bai, Ming-Zhu (external author)
  •   Huang, Xu-Feng
  •   Zhang, Yue (external author)
  •   Liu, Jing (external author)
  •   Hu, Min-Hao (external author)
  •   Zheng, Wei-Qian (external author)
  •   Jin, Fan (external author)

Publication Date


  • 2015

Citation


  • Yuan, M., Bai, M., Huang, X., Zhang, Y., Liu, J., Hu, M., Zheng, W. & Jin, F. (2015). Preimplantation exposure to Bisphenol A and Triclosan may lead to implantation failure in humans. BioMed Research International, 2015 184845-1-184845-9.

Scopus Eid


  • 2-s2.0-84940742503

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=1541&context=ihmri

Ro Metadata Url


  • http://ro.uow.edu.au/ihmri/523

Has Global Citation Frequency


Start Page


  • 184845-1

End Page


  • 184845-9

Volume


  • 2015

Place Of Publication


  • United States

Abstract


  • Endocrine disrupting chemicals (EDCs) are chemicals that have the capacity to interfere with normal endocrine systems. Two

    EDCs, bisphenol A (BPA) and triclosan (TCS), are mass-produced and are widespread.They both have estrogenic properties and

    similar chemical structures and pharmacokinetic features and have been detected in human fluids and tissues. Clinical evidence

    has suggested a positive association between BPA exposure and implantation failure in IVF patients. Studies inmouse models have

    suggested that preimplantation exposure to BPA and TCS can lead to implantation failure. This paper reviews the relationship

    between preimplantation exposure to BPA and TCS and implantation failure and discusses the remaining problems and possible

    solutions.

Authors


  •   Yuan, Mu (external author)
  •   Bai, Ming-Zhu (external author)
  •   Huang, Xu-Feng
  •   Zhang, Yue (external author)
  •   Liu, Jing (external author)
  •   Hu, Min-Hao (external author)
  •   Zheng, Wei-Qian (external author)
  •   Jin, Fan (external author)

Publication Date


  • 2015

Citation


  • Yuan, M., Bai, M., Huang, X., Zhang, Y., Liu, J., Hu, M., Zheng, W. & Jin, F. (2015). Preimplantation exposure to Bisphenol A and Triclosan may lead to implantation failure in humans. BioMed Research International, 2015 184845-1-184845-9.

Scopus Eid


  • 2-s2.0-84940742503

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=1541&context=ihmri

Ro Metadata Url


  • http://ro.uow.edu.au/ihmri/523

Has Global Citation Frequency


Start Page


  • 184845-1

End Page


  • 184845-9

Volume


  • 2015

Place Of Publication


  • United States