This paper reports the findings from a pilot study in which the Schedule for Individual Quality of Life (SEIQoL-DW) was used to determine how 15 at-risk Indigenous Australian male youths aged between 14 and 19 conceptualised their quality of life. The youths, who were referred with problems associated with drug and alcohol misuse and criminal activity, were attending a diversionary program run by an Indigenous organisation in the Northern Territory, Australia. Quality of life was measured before and at the end of the nine-day programme in order to evaluate outcomes. Program staff found the SEIQoL-DW to be particularly useful in identifying culturally specific quality of life domains, allowing interventions to focus on improving the life areas that were of particular value to individuals as well as recognizing any deficits in their understanding the options available to them. While a control group was not used, mean SEIQoL-DW scores increased significantly over the course of the program.