Aims: Guidelines recommend targeted use of antipsychotics in
delirium for specific symptoms however this approach has not
been evaluated in randomised trials. To compare the efficacy
of risperidone relative to placebo in the control of specific
delirium symptoms in palliative care patients (communication,
behaviour and/or perceptual disturbances on Nursing
Delirium Screening Scale) at 72 hours after study commencement.
Secondary aims were to compare haloperidol and
placebo; and risperidone and haloperidol.