An overview of the suitability of hydrogel-forming polymers for extrusion-based 3D-printing

Journal Article


Abstract


  • This review evaluates hydrogel-forming polymers that are suitable for soft tissue engineering with a focus on materials that can be fabricated using additive manufacturing (3D-printing). An overview of the specific material requirements for hydrogel-based tissue engineering constructs is presented. This is followed by an explanation of the various hydrogel-forming polymer classes that includes a detailed examination of material properties that are critical for extrusion printing. Specifically, mechanisms for hydrogel formation, degradation, and biological response, activity and compatibility are explored. A discussion of extrusion printing strategies for printable hydrogel-forming polymers is then presented in conjunction with a list of considerations to guide future tissue engineering developments.

Publication Date


  • 2015

Citation


  • Kirchmajer, D. M., Gorkin III, R. & in het Panhuis, M. (2015). An overview of the suitability of hydrogel-forming polymers for extrusion-based 3D-printing. Journal of Materials Chemistry B, 3 (20), 4105-4117.

Scopus Eid


  • 2-s2.0-84929224464

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/1446

Has Global Citation Frequency


Number Of Pages


  • 12

Start Page


  • 4105

End Page


  • 4117

Volume


  • 3

Issue


  • 20

Place Of Publication


  • United Kingdom

Abstract


  • This review evaluates hydrogel-forming polymers that are suitable for soft tissue engineering with a focus on materials that can be fabricated using additive manufacturing (3D-printing). An overview of the specific material requirements for hydrogel-based tissue engineering constructs is presented. This is followed by an explanation of the various hydrogel-forming polymer classes that includes a detailed examination of material properties that are critical for extrusion printing. Specifically, mechanisms for hydrogel formation, degradation, and biological response, activity and compatibility are explored. A discussion of extrusion printing strategies for printable hydrogel-forming polymers is then presented in conjunction with a list of considerations to guide future tissue engineering developments.

Publication Date


  • 2015

Citation


  • Kirchmajer, D. M., Gorkin III, R. & in het Panhuis, M. (2015). An overview of the suitability of hydrogel-forming polymers for extrusion-based 3D-printing. Journal of Materials Chemistry B, 3 (20), 4105-4117.

Scopus Eid


  • 2-s2.0-84929224464

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/1446

Has Global Citation Frequency


Number Of Pages


  • 12

Start Page


  • 4105

End Page


  • 4117

Volume


  • 3

Issue


  • 20

Place Of Publication


  • United Kingdom