Tehei, Moeava Dr

Head of the Targeted Nano-Therapies

  • School of Physics
  • Faculty of Engineering and Information Sciences
  • Centre for Medical Radiation Physics

Overview


Scientific research on the relation amongst dynamics, structure and function of proteins for optimisation of cancer treatment at the molecular drug target level. Elaboration of cancer therapies and imaging by combining the effects of targeted radiations and drugs or nanoparticles at the nano-scale level.

Top Publications


Research Overview


Available as Research Supervisor

Available for Collaborative Projects

Selected Publications


Investigator On


Impact Story


  • Brain cancer poses an exceptional clinical challenge because of poor prognosis and side effects of treatment. It affects all age groups including children with many adults being in their most productive years. Many brain cancer survivors suffer from cognitive and somatic side effects of the treatment with increased risks in children when cancer occurs before intellectual and physical development is completed. Glioblastoma is the most common and highly aggressive brain malignancy among all brain cancers. It requires potent treatments, including high dose radiation therapy due to significant radioresistance. This highlights the need for new technologies and treatments for this disease. Producing a more effective and synergistic chemo-radiation treatment that will improve survival and reduce morbidity would thus be clinically extremely valuable.

Available as Research Supervisor

Potential Supervision Topics


  • Design and application of new nanomaterials theranostic platforms for targeted treatment of cancer

  • Investigations into the dynamics involved in the magnetic transitions in Nanoparticles

  • Oncothermia in normal and cancerous cell lines

  • Targeted Nano-Therapies - Investigating uptake and distribution of high-Z in rodents for optimized radiation therapies guided multi-imaging

  • Targeted Nano-Therapies - Synchrotron Microbeam Activated Radiation Therapy

  • Scientific research on the relation amongst dynamics, structure and function of proteins for optimisation of cancer treatment at the molecular drug target level. Elaboration of cancer therapies and imaging by combining the effects of targeted radiations and drugs or nanoparticles at the nano-scale level.

    Biophysics, Nanomedicine, Radiation Biology, Neutron Scattering, Nanophysics, Solid State Physics

Advisees


  • Graduate Advising Relationship

    Degree Research Title Advisee
    Doctor of Philosophy Drug Delivery Multifunctional Systems Based on Nanoceramic Particles for Cancer Treatment Hsu, Nai-sheng
    Doctor of Philosophy Synthesis and Characterisation of Nanoparticles Such As Bismuth Ferrite For Implementation in MRI and CT Westlake, Matt
    Doctor of Philosophy Lanthanide nanoparticles for image guided multimodal therapies Engels, Elette
    Doctor of Philosophy (Integrated) Multimodal Therapy: A Combination of Oncothermia, Microbeam Radiation Therapy and Nano Therapy Hollis, Carolyn
    Master of Research - EIS Synthesis and Characterisation of Barium-Doped Nanoparticles of LaxMn03. O'Keefe, Alice
    Master of Philosophy - EIS Lanthanum Manganite nanoparticles combined with Methotrexate for radiation dose enhancement and theranostic applications Khochaiche, Abass
    Doctor of Philosophy 'Enhancement of Radiation Therapies Using High-Z Nanoparticles and Drugs' Valceski, Michael
    Doctor of Philosophy Investigation into the Use of Lanthanide Metal Oxide Nanoparticles for the Theranostic Treatment of Cancer Vogel, Sarah
    Doctor of Philosophy Improving the Efficacy of Radiotherapy for Cancer Treatment McDonald, Marjorie

Outreach Overview


  • EDITORIAL BOARD MEMBER
    Scientific Reports (Nature Publishing Group)

    PEER REVIEWER IN SCIENTIFIC JOURNALS
    Nanoscale
    Small
    Nanomedicine: Nanotechnology, Biology, and Medicine
    Physics Review Letters
    Physics Review E, A
    International Journal of Radiation Biology
    BBA - General Subjects
    Biophysical Journal
    Physical Chemistry Chemical Physics
    Interfaces
    Soft Matter
    The Journal of Physical Chemistry
    Journal of the American Chemical Society
    The FEBS Journal
    The Journal of Biological Chemistry
    European Journal of Biophysics

Full Name


  • Dr Moeava Tehei

Mailing Address


  • School of Physics - University of Wollongong

    Faculty of Engineering and Information Sciences

    Northfields Ave - Wollongong

    NSW

    2522

    Australia

Top Publications


Research Overview


Selected Publications


Investigator On


Impact Story


  • Brain cancer poses an exceptional clinical challenge because of poor prognosis and side effects of treatment. It affects all age groups including children with many adults being in their most productive years. Many brain cancer survivors suffer from cognitive and somatic side effects of the treatment with increased risks in children when cancer occurs before intellectual and physical development is completed. Glioblastoma is the most common and highly aggressive brain malignancy among all brain cancers. It requires potent treatments, including high dose radiation therapy due to significant radioresistance. This highlights the need for new technologies and treatments for this disease. Producing a more effective and synergistic chemo-radiation treatment that will improve survival and reduce morbidity would thus be clinically extremely valuable.

Potential Supervision Topics


  • Design and application of new nanomaterials theranostic platforms for targeted treatment of cancer

  • Investigations into the dynamics involved in the magnetic transitions in Nanoparticles

  • Oncothermia in normal and cancerous cell lines

  • Targeted Nano-Therapies - Investigating uptake and distribution of high-Z in rodents for optimized radiation therapies guided multi-imaging

  • Targeted Nano-Therapies - Synchrotron Microbeam Activated Radiation Therapy

  • Scientific research on the relation amongst dynamics, structure and function of proteins for optimisation of cancer treatment at the molecular drug target level. Elaboration of cancer therapies and imaging by combining the effects of targeted radiations and drugs or nanoparticles at the nano-scale level.

    Biophysics, Nanomedicine, Radiation Biology, Neutron Scattering, Nanophysics, Solid State Physics

Advisees


  • Graduate Advising Relationship

    Degree Research Title Advisee
    Doctor of Philosophy Drug Delivery Multifunctional Systems Based on Nanoceramic Particles for Cancer Treatment Hsu, Nai-sheng
    Doctor of Philosophy Synthesis and Characterisation of Nanoparticles Such As Bismuth Ferrite For Implementation in MRI and CT Westlake, Matt
    Doctor of Philosophy Lanthanide nanoparticles for image guided multimodal therapies Engels, Elette
    Doctor of Philosophy (Integrated) Multimodal Therapy: A Combination of Oncothermia, Microbeam Radiation Therapy and Nano Therapy Hollis, Carolyn
    Master of Research - EIS Synthesis and Characterisation of Barium-Doped Nanoparticles of LaxMn03. O'Keefe, Alice
    Master of Philosophy - EIS Lanthanum Manganite nanoparticles combined with Methotrexate for radiation dose enhancement and theranostic applications Khochaiche, Abass
    Doctor of Philosophy 'Enhancement of Radiation Therapies Using High-Z Nanoparticles and Drugs' Valceski, Michael
    Doctor of Philosophy Investigation into the Use of Lanthanide Metal Oxide Nanoparticles for the Theranostic Treatment of Cancer Vogel, Sarah
    Doctor of Philosophy Improving the Efficacy of Radiotherapy for Cancer Treatment McDonald, Marjorie

Outreach Overview


  • EDITORIAL BOARD MEMBER
    Scientific Reports (Nature Publishing Group)

    PEER REVIEWER IN SCIENTIFIC JOURNALS
    Nanoscale
    Small
    Nanomedicine: Nanotechnology, Biology, and Medicine
    Physics Review Letters
    Physics Review E, A
    International Journal of Radiation Biology
    BBA - General Subjects
    Biophysical Journal
    Physical Chemistry Chemical Physics
    Interfaces
    Soft Matter
    The Journal of Physical Chemistry
    Journal of the American Chemical Society
    The FEBS Journal
    The Journal of Biological Chemistry
    European Journal of Biophysics

Full Name


  • Dr Moeava Tehei

Mailing Address


  • School of Physics - University of Wollongong

    Faculty of Engineering and Information Sciences

    Northfields Ave - Wollongong

    NSW

    2522

    Australia

Geographic Focus