Lerch, Michael L. F.

Overview

Professor Michael Lerch graduated with a PhD in solid state physics in 1998. He was a founding member of the Centre for Medical Radiation Physics (CMRP) at the University of Wollongong (UOW). He is currently Head of the School of Physics at UOW. Michael is also Deputy Director of the CMRP and Leader of the Radiation Detection and Instrumentation Theme within the CMRP. The CMRP research outputs come under the Medical Physics field of research (FOR) at UOW and this FOR is ranked as being “well above world standard” (Australian Research Council Excellence in Research (ERA) initiative in 2018).

Michael applies his expertise of electronic properties of semiconductors to the design and development of novel, solid state based sensors and instrumentation for application in radiation medicine. He has played a major role in the development of real-time, solid state radiation dosimetry systems with millimetre and sub-millimetre spatial resolution.

Michael is also interested in the optimization of radiation medicine created by the physical and semiconducting properties of engineered nano-ceramics and semiconductor devices in different radiation field environments (e.g. photons or charged particles). He is interested in the real-world implementation and application of real-time devices designed to operate in vivo from a targeted diagnostic imaging and radiotherapy point of view.

Michael's extensive experience in cutting-edge instrumentation for radiation medicine (imaging and therapy) is demonstrated by several years of undergraduate and postgraduate teaching and research at UOW. He has published over 150 journal articles and has supervised more than 25 higher degree research students to completion since 2005. His research and development projects have been realised through national and international competitive research funding agencies.

Top Publications

Year	Title
2016	X-Tream quality assurance in synchrotron X-ray microbeam radiation therapy Published in Journal of Synchrotron Radiation
2014	High-Z nanostructured ceramics in radiotherapy: first evidence of Ta2O5-induced dose enhancement on radioresistant cancer cells in an MV photon field Published in Particle and Particle Systems Characterization
2017	Correction factors to convert microdosimetry measurements in silicon to tissue in ¹²C ion therapy Published in Physics in Medicine and Biology
2011	Dosimetry of intensive synchrotron microbeams Published in Radiation Measurements
2010	A silicon strip detector dose magnifying glass for IMRT dosimetry Published in Medical Physics
2009	MOSFET dosimetry with high spatial resolution in intense synchrotron-generated x-ray microbeams Published in Medical Physics
2012	Characterization of a novel two dimensional diode array the “magic plate” as a radiation detector for radiation therapy treatment Published in Medical Physics
2015	Characterization of a large area thinned silicon microdosimeter for space and particle therapy Published in IEEE Transactions on Nuclear Science
2013	Cerium oxide nanoparticles: influence of the high-Z component revealed on radioresistant 9L cell survival under X-ray irradiation Published in Nanomedicine
2016	In vivo rectal wall measurements during HDR prostate brachytherapy with MOSkin dosimeters integrated on a trans-rectal US probe: Comparison with planned and reconstructed doses Published in Radiotherapy and Oncology
2009	Microbeam radiation therapy: A Monte Carlo study of the influence of the source, multislit collimator, and beam divergence on microbeams Published in Medical Physics
2017	X-ray microbeam measurements with a high resolution scintillator fibre-optic dosimeter Published in Scientific Reports
2019	First experimental measurement of the effect of cardio-synchronous brain motion on the dose distribution during microbeam radiation therapy Published in Medical Physics

Research Areas

0299 - OTHER PHYSICAL SCIENCES

Available as Research Supervisor

Available for Collaborative Projects

Head Of

UOW School of Physics Head of School 2014 -

Member Of

Illawarra Health and Medical Research Institute Fellow 2016 -
Centre for Medical Radiation Physics, Deputy Director 2000 -

Selected Publications

Journal Article

Year	Title
2020	A solid-state microdosimeter for dose and radiation quality monitoring for astronauts in space Published In IEEE Transactions on Nuclear Science ISSN 1558-1578 Altmetric
2020	Characterization of a plastic dosimeter based on organic semiconductor photodiodes and scintillator Published In Physics and Imaging in Radiation Oncology Volume 14 Pages 48 - 52 Altmetric
2020	Characterization of an organic semiconductor diode for dosimetry in radiotherapy Published In Medical Physics Altmetric
2020	Evaluation of the PTW microDiamond in edge-on orientation for dosimetry in small fields Published In Journal of Applied Clinical Medical Physics ISSN 1526-9914 Altmetric
2020	Medipix detectors in radiation therapy for advanced quality-assurance Published In Radiation Measurements Volume 130 Pages 106211-1 - 106211-18 ISSN 1350-4487 Altmetric
2020	Na-doped ZnO UV filters with reduced photocatalytic activity for sunscreen applications Published In Journal of Materials Science Volume 55 Pages 2772 - 2786 ISSN 0022-2461 Altmetric
2020	On the Combined Effect of Silicon Oxide Thickness and Boron Implantation under the Gate in MOSFET Dosimeters Published In IEEE Transactions on Nuclear Science Volume 67 Pages 534 - 540 Altmetric
2020	Technical advances in X-ray microbeam radiation therapy Published In Physics in Medicine and Biology Volume 65 Pages 02TR01-1 - 02TR01-20 ISSN 0031-9155 Altmetric
2020	Toward personalized synchrotron microbeam radiation therapy Published In Scientific Reports Volume 10 Pages 8833-1 - 8833-13 ISSN 2045-2322 Altmetric
2020	Validation of Geant4 for silicon microdosimetry in heavy ion therapy Published In Physics in Medicine and Biology Volume 65 Page p. 045014 ISSN 0031-9155 Altmetric
2020	ZnO/CeO2 nanocomposite with low photocatalytic activity as efficient UV filters Published In Journal of Materials Science Altmetric
2019	2D monolithic silicon-diode array detectors in megavoltage photon beams: does the fabrication technology matter? A medical physicist’s perspective Published In Australasian Physical and Engineering Sciences in Medicine Volume Online First Pages 1 - 9 ISSN 0158-9938 Altmetric
2019	3D sensitive volume microdosimeter with improved tissue equivalency: Charge collection study and its application in ¹² C ion therapy Published In Journal of Physics: Conference Series Volume 1154 Pages 012012-1 - 012012-7 Altmetric
2019	BrachyView: Reconstruction of seed positions and volume of an LDR prostate brachytherapy patient plan using a baseline subtraction algorithm Published In Physica Medica: an international journal devoted to the applications of physics to medicine and biology Volume 66 Pages 66 - 76 ISSN 1724-191X Altmetric
2019	BrachyView: Verification of LDR patient plans - Hardware optimisation Published In Journal of Physics: Conference Series Volume 1154 Pages 012005-1 - 012005-5 Altmetric
2019	BrachyView: initial preclinical results for a real-time in-body HDR PBT source tracking system with simultaneous TRUS image fusion Published In Physics in Medicine and Biology Volume 64 Pages 085002-1 - 085002-12 ISSN 0031-9155 Altmetric
2019	Characterization of an "Edgeless" Dosimeter for Angular Independent Measurements in Advanced Radiotherapy Treatments Published In IEEE Transactions on Radiation and Plasma Medical Sciences Volume 3 Pages 579 - 587 Altmetric
2019	Evolution of Diamond based Microdosimetry Published In Journal of Physics: Conference Series Volume 1154 Pages 1 - 4 Altmetric
2019	Experimental characterization of magnetically focused electron contamination at the surface of a high-field inline MRI-linac Published In Medical Physics Volume 46 Pages 5780 - 5789 ISSN 0094-2405 Altmetric
2019	Fibre optic dosimetry in synchrotron microbeam radiation therapy Published In Journal of Physics: Conference Series Volume 1154 Pages 1 - 4 Altmetric
2019	First experimental measurement of the effect of cardio-synchronous brain motion on the dose distribution during microbeam radiation therapy Published In Medical Physics Volume Online First Pages 1 - 11 ISSN 0094-2405 Altmetric
2019	High spatial resolution scintillator dosimetry of synchrotron microbeams Published In Scientific Reports Volume 9 Pages 6873-1 - 6873-7 ISSN 2045-2322 Altmetric
2019	IBIC microscopy – The powerful tool for testing micron – Sized sensitive volumes in segmented radiation detectors used in synchrotron microbeam radiation and hadron therapies Published In Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms Volume 458 Pages 90 - 96 ISSN 0168-583X Altmetric
2019	Investigating variable RBE in a 12c minibeam field with microdosimetry and geant4 Published In Radiation Protection Dosimetry Volume 183 Pages 160 - 166 ISSN 0144-8420 Altmetric
2019	Nano-sunscreens – a double-edged sword in protecting consumers from harm: viewing Australian regulatory policies through the lenses of the European Union Published In Critical Reviews in Toxicology Volume 49 Pages 122 - 139 ISSN 1040-8444 Altmetric
2019	Polo-like kinase 1 inhibitor BI6727 sensitizes 9L gliosarcoma cells to ionizing irradiation Published In Biomedical Physics & Engineering Express Volume 5 Pages 067003-1 - 067003-9 Altmetric
2019	Preliminary epi-diode characterization for HDR brachytherapy quality assurance Published In Journal of Physics: Conference Series Volume 1154 Pages 012026-1 - 012026-7 Altmetric
2019	SOI Thin Microdosimeter Detectors for Low Energy Ions and Radiation Damage Studies Published In IEEE Transactions on Nuclear Science Volume 66 Pages 320 - 326 ISSN 1558-1578 Altmetric
2019	SOI Thin Microdosimeters for High LET Single Event Upset Studies in Fe, O, Xe and Cocktail Ion Beam Fields Published In IEEE Transactions on Nuclear Science Volume Online First Pages 1 - 8 ISSN 1558-1578 Altmetric
2019	Synthesis of methotrexate-loaded tantalum pentoxide–poly(acrylic acid) nanoparticles for controlled drug release applications Published In Journal of Colloid and Interface Science Volume 538 Pages 286 - 296 ISSN 0021-9797 Altmetric
2019	The effect of an air gap on a 2D monolithic silicon detector for relative dosimetry Published In Journal of Instrumentation Volume 14 Pages 1 - 20 ISSN 1748-0221 Altmetric
2019	Tissue equivalence of diamond for heavy charged particles Published In Radiation Measurements Volume 122 Pages 1 - 9 ISSN 1350-4487 Altmetric
2019	Two-dimensional solid-state array detectors: A technique for in vivo dose verification in a variable effective area Published In Journal of Applied Clinical Medical Physics Volume 20 Pages 88 - 94 ISSN 1526-9914 Altmetric
2019	Validation of a Monte Carlo simulation for Microbeam Radiation Therapy on the Imaging and Medical Beamline at the Australian Synchrotron Published In Scientific Reports Volume 9 Pages 1 - 14 ISSN 2045-2322 Altmetric
2018	"Characterization of ELEKTA SRS cone collimator using high spatial resolution monolithic silicon detector array" Published In Journal of Applied Clinical Medical Physics Volume Online First Pages 1 - 11 ISSN 1526-9914 Altmetric
2018	Characterisation and evaluation of a PNP strip detector for synchrotron microbeam radiation therapy Published In Biomedical Physics & Engineering Express Volume 4 Pages 044002-1 - 044002-15 Altmetric
2018	First in vitro evidence of modulated electro-hyperthermia treatment performance in combination with megavoltage radiation by clonogenic assay Published In Scientific Reports Volume 8 Pages 16608-1 - 16608-13 ISSN 2045-2322 Altmetric
2018	High spatial resolution microdosimetry with monolithic Delta E-E detector on C-12 beam: Monte Carlo simulations and experiment Published In Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment Volume 887 Pages 70 - 80 ISSN 0168-9002 Altmetric
2018	High toxicity of Bi(OH)3 and α-Bi2O3 nanoparticles towards malignant 9L and MCF-7 cells Published In Materials Science and Engineering C: Materials for Biological Applications Volume 93 Pages 958 - 967 ISSN 0928-4931 Altmetric
2018	In-field and out-of-file application in ¹²C ion therapy using fully 3D silicon microdosimeters Published In Radiation Measurements Volume 115 Pages 55 - 59 ISSN 1350-4487 Altmetric
2018	Investigation of track structure and condensed history physics models for applications in radiation dosimetry on a micro and nano scale in Geant4 Published In Biomedical Physics and Engineering Express Volume 4 Pages 024001-1 - 024001-11 Altmetric
2018	Measuring the excitations in a new S = 1/2 quantum spin chain material with competing interactions Published In Journal of Physics: Condensed Matter Volume 30 Pages 215602-1 - 215602-7 ISSN 0953-8984 Altmetric
2018	Radiosensitisation enhancement effect of BrUdR and Ta2O5 NSPs in combination with 5-Fluorouracil antimetabolite in kilovoltage and megavoltage radiation Published In Biomedical Physics and Engineering Express Volume 4 Pages 034001-1 - 034001-14 Altmetric
2018	Real-time high spatial resolution dose verification in stereotactic motion adaptive arc radiotherapy Published In Journal of Applied Clinical Medical Physics Volume 19 Pages 173 - 184 ISSN 1526-9914 Altmetric
2018	Semiconductor real-time quality assurance dosimetry in brachytherapy Published In Brachytherapy Volume 17 Pages 133 - 145 ISSN 1538-4721 Altmetric
2018	Synchrotron X-ray microbeam dosimetry with a 20 micrometre resolution scintillator fibre-optic dosimeter Published In Journal of Synchrotron Radiation Volume 25 Pages 826 - 832 ISSN 0909-0495 Altmetric
2018	The relative biological effectiveness for carbon, nitrogen, and oxygen ion beams using passive and scanning techniques evaluated with fully 3D silicon microdosimeters Published In Medical Physics Volume 45 Pages 2299 - 2308 ISSN 0094-2405 Altmetric
2018	Thin Silicon Microdosimeter utilizing 3D MEMS Fabrication Technology: Charge Collection Study and its application in mixed radiation fields Published In IEEE Transactions on Nuclear Science Volume 65 Pages 467 - 472 ISSN 1558-1578 Altmetric
2018	Thulium Oxide Nanoparticles: A new candidate for image-guided radiotherapy Published In Biomedical Physics and Engineering Express Volume 4 Pages 044001-1 - 044001-11 Altmetric
2018	TiO2/(BiO)2CO3 nanocomposites for ultraviolet filtration with reduced photocatalytic activity Published In Journal of Materials Chemistry C Volume 6 Pages 5639 - 5650 ISSN 2050-7534 Altmetric
2018	Time-of-flight spectrometry of ultra-short, polyenergetic proton bunches Published In Review of Scientific Instruments Volume 89 Pages 123302-1 - 123302-9 ISSN 0034-6748 Altmetric
2017	A 2D silicon detector array for quality assurance in small field dosimetry: DUO Published In Medical Physics Volume 44 Pages 628 - 636 ISSN 0094-2405 Altmetric
2017	A 3D lateral electrode structure for diamond based microdosimetry Published In Applied Physics Letters Volume 110 Pages 013503-1 - 013503-4 ISSN 0003-6951 Altmetric
2017	A convenient verification method of the entrance photo-neutron dose for an 18 MV medical linac using silicon p-i-n diodes Published In Radiation Measurements Volume 106 Pages 391 - 398 ISSN 1350-4487 Altmetric
2017	Applications of MOSkin dosimeters for quality assurance in gynecological HDR brachytherapy: An in-phantom feasibility study Published In Radiation Measurements Volume 106 Pages 399 - 404 ISSN 1350-4487 Altmetric
2017	BrachyView: Combining LDR seed positions with transrectal ultrasound imaging in a prostate gel phantom Published In Physica Medica: an international journal devoted to the applications of physics to medicine and biology Volume 34 Pages 55 - 64 ISSN 1724-191X Altmetric
2017	Characterization of proton pencil beam scanning and passive beam using a high spatial resolution solid-state microdosimeter Published In Medical Physics Volume 44 Pages 6085 - 6095 ISSN 0094-2405 Altmetric
2017	Clinical application of MOSkin dosimeters to rectal wall in vivo dosimetry in gynecological HDR brachytherapy Published In Physica Medica: an international journal devoted to the applications of physics to medicine and biology Volume 41 Pages 5 - 12 ISSN 1724-191X Altmetric
2017	Comparison of phantom materials for use in quality assurance of microbeam radiation therapy Published In Journal of Synchrotron Radiation Volume 24 Pages 866 - 876 ISSN 0909-0495 Altmetric
2017	Correction factors to convert microdosimetry measurements in silicon to tissue in ¹²C ion therapy Published In Physics in Medicine and Biology Volume 62 Pages 2055 - 2069 ISSN 0031-9155 Altmetric
2017	Development of a silicon diode detector for skin dosimetry in radiotherapy Published In Medical Physics Volume 44 Pages 5402 - 5412 ISSN 0094-2405 Altmetric
2017	Effect of scattered electrons on the 'Magic Plate' transmission array detector response Published In Journal of Physics: Conference Series Volume 777 Pages 012033-1 - 012033-4 Altmetric
2017	Experimental studies with two novel silicon detectors for the development of time-of-flight spectrometry of laser-accelerated proton beams Published In Journal of Physics: Conference Series Volume 777 Pages 012018-1 - 012018-4 Altmetric
2017	Feasibility study of a novel multi-strip silicon detector for use in proton therapy range verification quality assurance Published In Radiation Measurements Volume 106 Pages 378 - 384 ISSN 1350-4487 Altmetric
2017	High-resolution fiber-optic dosimeters for microbeam radiation therapy Published In Medical Physics Volume 44 Pages 1965 - 1968 ISSN 0094-2405 Altmetric
2017	Impact of a monolithic silicon detector operating in transmission mode on clinical photon beams Published In Physica Medica: an international journal devoted to the applications of physics to medicine and biology Volume 43 Pages 114 - 119 ISSN 1724-191X Altmetric
2017	In vitro investigation of the dose-rate effect on the biological effectiveness of megavoltage X-ray radiation doses Published In Applied Radiation and Isotopes Volume 128 Pages 114 - 119 ISSN 0969-8043 Altmetric
2017	Initial testing of a pixelated silicon detector prototype in proton therapy Published In Journal of Applied Clinical Medical Physics Volume 18 Pages 315 - 324 ISSN 1526-9914 Altmetric
2017	Innovative detectors for quality assurance dosimetry in SBRT of stationary and movable targets Published In Journal of Physics: Conference Series Volume 777 Pages 012014-1 - 012014-4 Altmetric
2017	Introducing dynamic dosimaging: Potential applications for MRI-linac Published In Journal of Physics: Conference Series Volume 777 Pages 012007-1 - 012007-5 Altmetric
2017	Microdosimetric measurements of a clinical proton beam with micrometer-sized solid-state detector Published In Medical Physics Volume 44 Pages 6029 - 6037 ISSN 0094-2405 Altmetric
2017	Nanostructures, concentrations and energies: an ideal equation to extend therapeutic efficiency on radioresistant 9L tumour cells using Ta2O5 ceramic nanostructured particles Published In Biomedical Physics & Engineering Express Volume 3 Pages 015018-1 - 015018-13 Altmetric
2017	New 3D Silicon detectors for dosimetry in Microbeam Radiation Therapy Published In Journal of Physics: Conference Series Volume 777 Pages 012009-1 - 012009-5 Altmetric
2017	New silicon microdosimetry probes for RBE and biological dose studies using stationary and movable targets in ¹²C ion therapy Published In Journal of Physics: Conference Series Volume 777 Pages 012019-1 - 012019-4 Altmetric
2017	Optimisation of output factor measurements using the Magic Plate 512 silicon dosimeter array in small megavoltage photon fields Published In Journal of Physics: Conference Series Volume 777 Pages 012022-1 - 012022-5 Altmetric
2017	RBE study using solid state microdosimetry in heavy ion therapy Published In Radiation Measurements Volume 106 Pages 512 - 518 ISSN 1350-4487 Altmetric
2017	Radiation response and basic dosimetric characterisation of the 'Magic Plate' Published In Journal of Physics: Conference Series Volume 777 Pages 012034-1 - 012034-4 Altmetric
2017	Study of the correlation between rectal wall in vivo dosimetry performed with MOSkins and implant modification during TRUS-guided HDR prostate brachytherapy Published In Radiation Measurements Volume 106 Pages 385 - 390 ISSN 1350-4487 Altmetric
2017	Synchrotron activation radiotherapy: Effects of dose-rate and energy spectra to tantalum oxide nanoparticles selective tumour cell radiosensitization enhancement Published In Journal of Physics: Conference Series Volume 777 Pages 012011-1 - 012011-4 Altmetric
2017	Technical Note: Angular dependence of a 2D monolithic silicon diode array for small field dosimetry Published In Medical Physics Volume 44 Pages 4313 - 4321 ISSN 0094-2405 Altmetric
2017	The angular dependence of a two dimensional monolithic detector array for dosimetry in small radiation fields Published In Journal of Physics: Conference Series Volume 777 Pages 012020-1 - 012020-4 Altmetric
2017	Thermoluminescence dose response of photon irradiated NaCl: Unified interaction model analysis of the dependence of the supralinearity on photon energy Published In Radiation Measurements Volume 106 Pages 455 - 458 ISSN 1350-4487 Altmetric
2017	X-Tream dosimetry of highly brilliant X-ray microbeams in the MRT hutch of the Australian Synchrotron Published In Radiation Measurements Volume 106 Pages 405 - 411 ISSN 1350-4487 Altmetric
2017	X-ray microbeam measurements with a high resolution scintillator fibre-optic dosimeter Published In Scientific Reports Volume 7 Pages 12450-1 - 12450-7 ISSN 2045-2322 Altmetric
2016	Absorbed dose-to-water protocol applied to synchrotron-generated x-rays at very high dose rates Published In Physics in Medicine and Biology Volume 61 Pages N349 - N361 ISSN 0031-9155 Altmetric
2016	Analytical modelling and simulation of single and double cone pinholes for real-time in-body tracking of an HDR brachytherapy source Published In IEEE Transactions on Nuclear Science Volume 63 Pages 1375 - 1385 ISSN 1558-1578 Altmetric
2016	Beam perturbation characteristics of a 2D transmission silicon diode array, Magic Plate Published In Journal of Applied Clinical Medical Physics Volume 17 Pages 85 - 98 ISSN 1526-9914
2016	BrachyView: multiple seed position reconstruction and comparison with CT post-implant dosimetry Published In Journal of Instrumentation Volume 11 Pages P05002-1 - P05002-16 ISSN 1748-0221 Altmetric
2016	Characterisation of silicon diode arrays for dosimetry in external beam radiation therapy Published In IEEE Transactions on Nuclear Science Volume 63 Pages 1808 - 1817 ISSN 1558-1578 Altmetric
2016	Dose verification of eye plaque brachytherapy using spectroscopic dosimetry Published In Australasian Physical and Engineering Sciences in Medicine Volume 39 Pages 627 - 632 ISSN 0158-9938 Altmetric
2016	First proof of bismuth oxide nanoparticles as efficient radiosensitisers on highly radioresistant cancer cells Published In Physica Medica: an international journal devoted to the applications of physics to medicine and biology Volume 32 Pages 1444 - 1452 ISSN 1724-191X Altmetric
2016	In vivo rectal wall measurements during HDR prostate brachytherapy with MOSkin dosimeters integrated on a trans-rectal US probe: Comparison with planned and reconstructed doses Published In Radiotherapy and Oncology Volume 118 Pages 148 - 153 ISSN 0167-8140 Altmetric
2016	Initial experiments with gel-water: towards MRI-linac dosimetry and imaging Published In Australasian Physical and Engineering Sciences in Medicine Volume 39 Pages 921 - 932 ISSN 0158-9938 Altmetric
2016	Local dose enhancement of proton therapy by ceramic oxide nanoparticles investigated with Geant4 simulations Published In Physica Medica: an international journal devoted to the applications of physics to medicine and biology Volume 32 Pages 1584 - 1593 ISSN 1724-191X Altmetric
2016	Multi-strip silicon sensors for beam array monitoring in micro-beam radiation therapy Published In Physica Medica: an international journal devoted to the applications of physics to medicine and biology Volume 32 Pages 1795 - 1800 ISSN 1724-191X Altmetric
2016	Optimizing dose enhancement with Ta2O5 nanoparticles for synchrotron microbeam activated radiation therapy Published In Physica Medica: an international journal devoted to the applications of physics to medicine and biology Volume 32 Pages 1852 - 1861 ISSN 1724-191X Altmetric
2016	Real-time eye lens dose monitoring during cerebral angiography procedures Published In European Journal of Radiology Volume 26 Pages 79 - 86 ISSN 0720-048X Altmetric
2016	Study of the effect of ceramic TaO₅ nanoparticle distribution on cellular dose enhancement in a kilovoltage photon field Published In Physica Medica: an international journal devoted to the applications of physics to medicine and biology Volume 32 Pages 1216 - 1224 ISSN 1724-191X Altmetric
2016	Synthesis-dependent surface defects and morphology of hematite nanoparticles and their effect on cytotoxicity in vitro Published In ACS Applied Materials and Interfaces Volume 8 Pages 5867 - 5876 ISSN 1944-8244 Altmetric
2016	X-Tream quality assurance in synchrotron X-ray microbeam radiation therapy Published In Journal of Synchrotron Radiation Volume 23 Pages 1180 - 1190 ISSN 0909-0495 Altmetric
2015	MagicPlate-512: a 2D silicon detector array for quality assurance of stereotactic motion adaptive radiotherapy Published In Medical Physics Volume 42 Pages 2992 - 3004 ISSN 0094-2405 Altmetric
2015	2D mapping of the MV photon fluence and 3D dose reconstruction in real time for quality assurance during radiotherapy treatment Published In Journal of Instrumentation Volume 10 Pages 1 - 14 ISSN 1748-0221 Altmetric
2015	3D bridge microdosimeter: Charge collection study and application to RBE studies in 12C radiation therapy Published In Journal and Proceedings of the Royal Society of New South Wales Volume 148 Pages 44 - 51 ISSN 0035-9173
2015	3D-mesa 'bridge' silicon microdosimeter: charge collection study and application to RBE studies in 12C radiation therapy Published In IEEE Transactions on Nuclear Science Volume 62 Pages 504 - 511 ISSN 1558-1578 Altmetric
2015	3d silicon microdosimetry and RBE study using 12C ion of different energies Published In IEEE Transactions on Nuclear Science Volume 62 Pages 3027 - 3033 ISSN 1558-1578 Altmetric
2015	A new virtual ring-based system matrix generator for iterative image reconstruction in high resolution small volume PET systems Published In Physics in Medicine and Biology Volume 60 Pages 6949 - 6973 ISSN 0031-9155 Altmetric

Investigator On

Year	Title
2016 - 2020	3D-BrachyView: a 3D real-time virtual reality intra-operative Quality Assurance system for brachytherapy Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Development Grant
2019	Investigating the impact of detector packaging upon angular and energy dependence of the PTW microdiamond Awarded by: Australian Nuclear Science and Technology Organisation (ANSTO) Funding Scheme: Australian Synchrotron Access Program
2019	Microbeam radiation therapy at 4T: Dosimetric characterisation in preparation for an in-vivo brain cancer treatment study Awarded by: Australian Nuclear Science and Technology Organisation (ANSTO) Funding Scheme: Australian Synchrotron Access Program
2019	What can new developments in X-Tream Dosimetry teach us for the utilization of dose enhancement in experimental microbeam radiotheraphy and clinical radiotherapy? Awarded by: Deutscher Akademischer Austausch Dienst (DAAD) Funding Scheme: Australia Germany Joint Cooperation Scheme
2015 - 2018	Design and application of new nanomaterials theranostic platforms for targeted treatment of cancer Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2015 - 2018	X-RATE: A novel radiation detector platform to realise new opportunities in radiotherapy at the Australian Synchrotron Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Development Grant
2016	Far-Infrared Spectroscopy of Quantum Spin chain: PdCuSO4(HO)2 Awarded by: Australian Synchrotron Company P/L Funding Scheme: Travel Grant
2016	Investigation of the effects of tantalum pentoxide and bismuth oxide nano particles on 9L gilosarcoma and MDCK etc Awarded by: Australian Synchrotron Company P/L Funding Scheme: Travel Grant
2016	Small animal stereotaxic instrument and microinjection unit Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2015 - 2016	New silicon dosimetry probes with an isolated 3D sensitive volume for pre-treatment quality assurance of dynamic microbeam radiation therapy Awarded by: Australian Synchrotron Company P/L Funding Scheme: Travel Grant
2015	Investigation of the effects of tantalum pentoxide and bismuth oxide nano particles on 9L gliosarcoma and MDCK non cancerour cells using both synchrotron generated broad and micro-beams monitored by the X-tream dosimetry system. Awarded by: Australian Synchrotron Research Program Funding Scheme: Travel Grant
2014	Using Nonlinear Effects as a Method for cheap THz Radiation Production Awarded by: Australian Synchrotron Company P/L Funding Scheme: Travel Grant
2013	Innovative methods in radiotherapy and radiosurgery using synchrotron radiation Awarded by: The Research Council of Norway Funding Scheme: European Cooperation in the field of Scientific and Technical Research - COST
2013	Silicon based 3D mini- and microdosometer Awarded by: The Research Council of Norway Funding Scheme: European Cooperation in the field of Scientific and Technical Research - COST
2012	Australian Synchrotron Access Program Awarded by: Australian Research Council (ARC) Funding Scheme: Special Research Initiatives
2012	Improving radiation therapy of static and moving targets using high spatial resolution real-time dosimeters Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2011	Dosimetry in Synchrotron X-Ray Microbeam Radiation Therapy Awarded by: Australian Synchrotron Company P/L Funding Scheme: Travel Grant
2011	Radiosurgery with sub-millimeter x-ray beams: development of the X-Tream real-time beam monitoring and Quality Assurance system Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Development Grant
2010	BrachyVision: A novel multipurpose probe for in-body radiation imaging and dosimetry. Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Development Grant
2010	Development of innovative radiation detectors and computational techniques for improving quality of life Awarded by: Australian Research Council (ARC) Funding Scheme: Discovery Projects
2010	New solid state detectors for real time absolute dosimetry in microbeam radiation therapy Awarded by: European Synchrotron Radiation Facility Funding Scheme: Beam Time
2010	New solid state detectors for real time absolute dosimetry in microbeam radiation therapy Awarded by: Australian Synchrotron Research Program Funding Scheme: Travel Grant
2009	Development of a real time multichannel radiation dosimetry system for Microbeam Radiation Therapy (MRT) quality assurance and further studies in magneto-MRT Awarded by: Australian Synchrotron Research Program Funding Scheme: Travel Grant
2009	High spatial resolution dosimetry for radioactive plaques used for radiotherapy of eye lesions Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2008	Characterisation of innovative Si radiation detectors for high spatial resolution isotopic imaging Awarded by: Australian Institute of Nuclear Science and Engineering (AINSE) Funding Scheme: Research Award
2008	IBIC studies of detectors for synchrotron X-ray dosimetry Awarded by: Australian Institute of Nuclear Science and Engineering (AINSE) Funding Scheme: Research Award
2007	IBIC studies of detectors for synchrotron X-ray dosimetry Awarded by: Australian Institute of Nuclear Science and Engineering (AINSE) Funding Scheme: Grant
2007	Magnetic-Field Enhancement Radiotherapy - A new concept in Cancer treatment Awarded by: Cancer Institute NSW Funding Scheme: Research Innovation Grants
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	Comparison and evaluation of alternate dosimeter technologies for MRT Awarded by: Australian Synchrotron Company P/L Funding Scheme: Travel Grant
	Development of radiation detectors to better understand ion interactions Awarded by: Australian Research Council (ARC) Funding Scheme: Discovery Projects
	Enhancing synchrotron microbeam radiation therapy in vivo with high-Z nanoparticles Awarded by: Australian Synchrotron Research Program Funding Scheme: Imaging and Medical Beamline
	Fast and efficient assessment of dose in small targets in radiotherapy: Effect of motion in clinical research and implementation of dynamic therapy Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
	Investigation of the effects of thulium oxide nanoparticles and anti-cancer drugs on tumorous 9L gliosarcoma and MDCK non cancerous cells using micro-beams monitored by the X-tream dosimetry system Awarded by: Australian Synchrotron Company P/L Funding Scheme: Travel Grant
	Investigation of the effects of thulium oxide nanoparticles and anti-cancer drugs on tumorous 9L gliosarcoma and MDCK non cancerous cells using micro-beams monitored by the x-tream dosimetry system and characterisation of DNA damage-repair with yH2AX Awarded by: Australian Synchrotron Research Program Funding Scheme: Beamtime at the AS XAS Beamline
	Low temperature THz spectroscopy of artists pigments Awarded by: Australian Synchrotron Company P/L Funding Scheme: Travel Grant
	Radiotheraphy 'dry-run' as feasibility study for veterinary trials in hutch 3B Awarded by: Australian Synchrotron Research Program Funding Scheme: Imaging and Medical Beamline
	Refining synchrotron microbeam radiation therapy techniques in vivo Awarded by: Australian Nuclear Science and Technology Organisation (ANSTO) Funding Scheme: Australian Synchrotron Access Program
	Silicon on diamond strip detectors for MRT Awarded by: Australian Synchrotron Company P/L Funding Scheme: Travel Grant
	Transmission detectors for real time beam monitoring Awarded by: Australian Synchrotron Research Program Funding Scheme: Imaging and Medical Beamline

Impact Story

Available as Research Supervisor

Advisees

Graduate Advising Relationship

Degree	Research Title	Advisee
Doctor of Philosophy	Microbeam Radiation Therapy: Development of Instrumentation and Software Tools for Quality Assurance	Cameron, Matthew
Doctor of Philosophy	Development of a silicon-on-diamond dosimeter for Microbeam Radiation Therapy	Dipuglia, Andrew
Doctor of Philosophy	Advance Nanocomposites for health protection applications	Mueen, Rafid Abdlateef
Doctor of Philosophy	Assessing MRI-linac based Radiotherapy Uncertainties	Roberts, Natalia
Master of Philosophy	Single-Molecule Studies of Exonuclease Proteins	Muir, Ryan
Doctor of Philosophy	Lanthanide nanoparticles for image guided multimodal therapies	Engels, Elette
Doctor of Philosophy (Integrated)	Multimodal Therapy: A Combination of Oncothermia, Microbeam Radiation Therapy and Nano Therapy	Hollis, Carolyn
Master of Research - EIS	Synthesis and characterisation of barium-doped lanthanum manganite nanoparticles	O'Keefe, Alice
Doctor of Philosophy	Development and Experimental Validation of a Monte Carlo Based Treatment Planning System for Microbeam Radiation Therapy	Paino, Jason
Doctor of Philosophy	'Enhancement of Radiation Therapies Using High-Z Nanoparticles and Drugs'	Valceski, Michael
Doctor of Philosophy	Investigation into the Use of Lanthanide Metal Oxide Nanoparticles for the Theranostic Treatment of Cancer	Vogel, Sarah
Master of Philosophy - EIS	Nature of collapse induced radiation (Pre-Hawking radiation) generated by the excitation of fields in the spacetime during the process of gravitational collapse of a Schwarzschild black hole	Shrestha, Ankit

Keywords

semiconductors, radiation dosimetry, radiation therapy, solid state dosimetry, medical physics, microbeam

Top Publications

Year	Title
2016	X-Tream quality assurance in synchrotron X-ray microbeam radiation therapy Published in Journal of Synchrotron Radiation
2014	High-Z nanostructured ceramics in radiotherapy: first evidence of Ta2O5-induced dose enhancement on radioresistant cancer cells in an MV photon field Published in Particle and Particle Systems Characterization
2017	Correction factors to convert microdosimetry measurements in silicon to tissue in ¹²C ion therapy Published in Physics in Medicine and Biology
2011	Dosimetry of intensive synchrotron microbeams Published in Radiation Measurements
2010	A silicon strip detector dose magnifying glass for IMRT dosimetry Published in Medical Physics
2009	MOSFET dosimetry with high spatial resolution in intense synchrotron-generated x-ray microbeams Published in Medical Physics
2012	Characterization of a novel two dimensional diode array the “magic plate” as a radiation detector for radiation therapy treatment Published in Medical Physics
2015	Characterization of a large area thinned silicon microdosimeter for space and particle therapy Published in IEEE Transactions on Nuclear Science
2013	Cerium oxide nanoparticles: influence of the high-Z component revealed on radioresistant 9L cell survival under X-ray irradiation Published in Nanomedicine
2016	In vivo rectal wall measurements during HDR prostate brachytherapy with MOSkin dosimeters integrated on a trans-rectal US probe: Comparison with planned and reconstructed doses Published in Radiotherapy and Oncology
2009	Microbeam radiation therapy: A Monte Carlo study of the influence of the source, multislit collimator, and beam divergence on microbeams Published in Medical Physics
2017	X-ray microbeam measurements with a high resolution scintillator fibre-optic dosimeter Published in Scientific Reports
2019	First experimental measurement of the effect of cardio-synchronous brain motion on the dose distribution during microbeam radiation therapy Published in Medical Physics

Research Areas

0299 - OTHER PHYSICAL SCIENCES

Head Of

UOW School of Physics Head of School 2014 -

Member Of

Illawarra Health and Medical Research Institute Fellow 2016 -
Centre for Medical Radiation Physics, Deputy Director 2000 -

Selected Publications

Journal Article

Year	Title
2020	A solid-state microdosimeter for dose and radiation quality monitoring for astronauts in space Published In IEEE Transactions on Nuclear Science ISSN 1558-1578 Altmetric
2020	Characterization of a plastic dosimeter based on organic semiconductor photodiodes and scintillator Published In Physics and Imaging in Radiation Oncology Volume 14 Pages 48 - 52 Altmetric
2020	Characterization of an organic semiconductor diode for dosimetry in radiotherapy Published In Medical Physics Altmetric
2020	Evaluation of the PTW microDiamond in edge-on orientation for dosimetry in small fields Published In Journal of Applied Clinical Medical Physics ISSN 1526-9914 Altmetric
2020	Medipix detectors in radiation therapy for advanced quality-assurance Published In Radiation Measurements Volume 130 Pages 106211-1 - 106211-18 ISSN 1350-4487 Altmetric
2020	Na-doped ZnO UV filters with reduced photocatalytic activity for sunscreen applications Published In Journal of Materials Science Volume 55 Pages 2772 - 2786 ISSN 0022-2461 Altmetric
2020	On the Combined Effect of Silicon Oxide Thickness and Boron Implantation under the Gate in MOSFET Dosimeters Published In IEEE Transactions on Nuclear Science Volume 67 Pages 534 - 540 Altmetric
2020	Technical advances in X-ray microbeam radiation therapy Published In Physics in Medicine and Biology Volume 65 Pages 02TR01-1 - 02TR01-20 ISSN 0031-9155 Altmetric
2020	Toward personalized synchrotron microbeam radiation therapy Published In Scientific Reports Volume 10 Pages 8833-1 - 8833-13 ISSN 2045-2322 Altmetric
2020	Validation of Geant4 for silicon microdosimetry in heavy ion therapy Published In Physics in Medicine and Biology Volume 65 Page p. 045014 ISSN 0031-9155 Altmetric
2020	ZnO/CeO2 nanocomposite with low photocatalytic activity as efficient UV filters Published In Journal of Materials Science Altmetric
2019	2D monolithic silicon-diode array detectors in megavoltage photon beams: does the fabrication technology matter? A medical physicist’s perspective Published In Australasian Physical and Engineering Sciences in Medicine Volume Online First Pages 1 - 9 ISSN 0158-9938 Altmetric
2019	3D sensitive volume microdosimeter with improved tissue equivalency: Charge collection study and its application in ¹² C ion therapy Published In Journal of Physics: Conference Series Volume 1154 Pages 012012-1 - 012012-7 Altmetric
2019	BrachyView: Reconstruction of seed positions and volume of an LDR prostate brachytherapy patient plan using a baseline subtraction algorithm Published In Physica Medica: an international journal devoted to the applications of physics to medicine and biology Volume 66 Pages 66 - 76 ISSN 1724-191X Altmetric
2019	BrachyView: Verification of LDR patient plans - Hardware optimisation Published In Journal of Physics: Conference Series Volume 1154 Pages 012005-1 - 012005-5 Altmetric
2019	BrachyView: initial preclinical results for a real-time in-body HDR PBT source tracking system with simultaneous TRUS image fusion Published In Physics in Medicine and Biology Volume 64 Pages 085002-1 - 085002-12 ISSN 0031-9155 Altmetric
2019	Characterization of an "Edgeless" Dosimeter for Angular Independent Measurements in Advanced Radiotherapy Treatments Published In IEEE Transactions on Radiation and Plasma Medical Sciences Volume 3 Pages 579 - 587 Altmetric
2019	Evolution of Diamond based Microdosimetry Published In Journal of Physics: Conference Series Volume 1154 Pages 1 - 4 Altmetric
2019	Experimental characterization of magnetically focused electron contamination at the surface of a high-field inline MRI-linac Published In Medical Physics Volume 46 Pages 5780 - 5789 ISSN 0094-2405 Altmetric
2019	Fibre optic dosimetry in synchrotron microbeam radiation therapy Published In Journal of Physics: Conference Series Volume 1154 Pages 1 - 4 Altmetric
2019	First experimental measurement of the effect of cardio-synchronous brain motion on the dose distribution during microbeam radiation therapy Published In Medical Physics Volume Online First Pages 1 - 11 ISSN 0094-2405 Altmetric
2019	High spatial resolution scintillator dosimetry of synchrotron microbeams Published In Scientific Reports Volume 9 Pages 6873-1 - 6873-7 ISSN 2045-2322 Altmetric
2019	IBIC microscopy – The powerful tool for testing micron – Sized sensitive volumes in segmented radiation detectors used in synchrotron microbeam radiation and hadron therapies Published In Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms Volume 458 Pages 90 - 96 ISSN 0168-583X Altmetric
2019	Investigating variable RBE in a 12c minibeam field with microdosimetry and geant4 Published In Radiation Protection Dosimetry Volume 183 Pages 160 - 166 ISSN 0144-8420 Altmetric
2019	Nano-sunscreens – a double-edged sword in protecting consumers from harm: viewing Australian regulatory policies through the lenses of the European Union Published In Critical Reviews in Toxicology Volume 49 Pages 122 - 139 ISSN 1040-8444 Altmetric
2019	Polo-like kinase 1 inhibitor BI6727 sensitizes 9L gliosarcoma cells to ionizing irradiation Published In Biomedical Physics & Engineering Express Volume 5 Pages 067003-1 - 067003-9 Altmetric
2019	Preliminary epi-diode characterization for HDR brachytherapy quality assurance Published In Journal of Physics: Conference Series Volume 1154 Pages 012026-1 - 012026-7 Altmetric
2019	SOI Thin Microdosimeter Detectors for Low Energy Ions and Radiation Damage Studies Published In IEEE Transactions on Nuclear Science Volume 66 Pages 320 - 326 ISSN 1558-1578 Altmetric
2019	SOI Thin Microdosimeters for High LET Single Event Upset Studies in Fe, O, Xe and Cocktail Ion Beam Fields Published In IEEE Transactions on Nuclear Science Volume Online First Pages 1 - 8 ISSN 1558-1578 Altmetric
2019	Synthesis of methotrexate-loaded tantalum pentoxide–poly(acrylic acid) nanoparticles for controlled drug release applications Published In Journal of Colloid and Interface Science Volume 538 Pages 286 - 296 ISSN 0021-9797 Altmetric
2019	The effect of an air gap on a 2D monolithic silicon detector for relative dosimetry Published In Journal of Instrumentation Volume 14 Pages 1 - 20 ISSN 1748-0221 Altmetric
2019	Tissue equivalence of diamond for heavy charged particles Published In Radiation Measurements Volume 122 Pages 1 - 9 ISSN 1350-4487 Altmetric
2019	Two-dimensional solid-state array detectors: A technique for in vivo dose verification in a variable effective area Published In Journal of Applied Clinical Medical Physics Volume 20 Pages 88 - 94 ISSN 1526-9914 Altmetric
2019	Validation of a Monte Carlo simulation for Microbeam Radiation Therapy on the Imaging and Medical Beamline at the Australian Synchrotron Published In Scientific Reports Volume 9 Pages 1 - 14 ISSN 2045-2322 Altmetric
2018	"Characterization of ELEKTA SRS cone collimator using high spatial resolution monolithic silicon detector array" Published In Journal of Applied Clinical Medical Physics Volume Online First Pages 1 - 11 ISSN 1526-9914 Altmetric
2018	Characterisation and evaluation of a PNP strip detector for synchrotron microbeam radiation therapy Published In Biomedical Physics & Engineering Express Volume 4 Pages 044002-1 - 044002-15 Altmetric
2018	First in vitro evidence of modulated electro-hyperthermia treatment performance in combination with megavoltage radiation by clonogenic assay Published In Scientific Reports Volume 8 Pages 16608-1 - 16608-13 ISSN 2045-2322 Altmetric
2018	High spatial resolution microdosimetry with monolithic Delta E-E detector on C-12 beam: Monte Carlo simulations and experiment Published In Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment Volume 887 Pages 70 - 80 ISSN 0168-9002 Altmetric
2018	High toxicity of Bi(OH)3 and α-Bi2O3 nanoparticles towards malignant 9L and MCF-7 cells Published In Materials Science and Engineering C: Materials for Biological Applications Volume 93 Pages 958 - 967 ISSN 0928-4931 Altmetric
2018	In-field and out-of-file application in ¹²C ion therapy using fully 3D silicon microdosimeters Published In Radiation Measurements Volume 115 Pages 55 - 59 ISSN 1350-4487 Altmetric
2018	Investigation of track structure and condensed history physics models for applications in radiation dosimetry on a micro and nano scale in Geant4 Published In Biomedical Physics and Engineering Express Volume 4 Pages 024001-1 - 024001-11 Altmetric
2018	Measuring the excitations in a new S = 1/2 quantum spin chain material with competing interactions Published In Journal of Physics: Condensed Matter Volume 30 Pages 215602-1 - 215602-7 ISSN 0953-8984 Altmetric
2018	Radiosensitisation enhancement effect of BrUdR and Ta2O5 NSPs in combination with 5-Fluorouracil antimetabolite in kilovoltage and megavoltage radiation Published In Biomedical Physics and Engineering Express Volume 4 Pages 034001-1 - 034001-14 Altmetric
2018	Real-time high spatial resolution dose verification in stereotactic motion adaptive arc radiotherapy Published In Journal of Applied Clinical Medical Physics Volume 19 Pages 173 - 184 ISSN 1526-9914 Altmetric
2018	Semiconductor real-time quality assurance dosimetry in brachytherapy Published In Brachytherapy Volume 17 Pages 133 - 145 ISSN 1538-4721 Altmetric
2018	Synchrotron X-ray microbeam dosimetry with a 20 micrometre resolution scintillator fibre-optic dosimeter Published In Journal of Synchrotron Radiation Volume 25 Pages 826 - 832 ISSN 0909-0495 Altmetric
2018	The relative biological effectiveness for carbon, nitrogen, and oxygen ion beams using passive and scanning techniques evaluated with fully 3D silicon microdosimeters Published In Medical Physics Volume 45 Pages 2299 - 2308 ISSN 0094-2405 Altmetric
2018	Thin Silicon Microdosimeter utilizing 3D MEMS Fabrication Technology: Charge Collection Study and its application in mixed radiation fields Published In IEEE Transactions on Nuclear Science Volume 65 Pages 467 - 472 ISSN 1558-1578 Altmetric
2018	Thulium Oxide Nanoparticles: A new candidate for image-guided radiotherapy Published In Biomedical Physics and Engineering Express Volume 4 Pages 044001-1 - 044001-11 Altmetric
2018	TiO2/(BiO)2CO3 nanocomposites for ultraviolet filtration with reduced photocatalytic activity Published In Journal of Materials Chemistry C Volume 6 Pages 5639 - 5650 ISSN 2050-7534 Altmetric
2018	Time-of-flight spectrometry of ultra-short, polyenergetic proton bunches Published In Review of Scientific Instruments Volume 89 Pages 123302-1 - 123302-9 ISSN 0034-6748 Altmetric
2017	A 2D silicon detector array for quality assurance in small field dosimetry: DUO Published In Medical Physics Volume 44 Pages 628 - 636 ISSN 0094-2405 Altmetric
2017	A 3D lateral electrode structure for diamond based microdosimetry Published In Applied Physics Letters Volume 110 Pages 013503-1 - 013503-4 ISSN 0003-6951 Altmetric
2017	A convenient verification method of the entrance photo-neutron dose for an 18 MV medical linac using silicon p-i-n diodes Published In Radiation Measurements Volume 106 Pages 391 - 398 ISSN 1350-4487 Altmetric
2017	Applications of MOSkin dosimeters for quality assurance in gynecological HDR brachytherapy: An in-phantom feasibility study Published In Radiation Measurements Volume 106 Pages 399 - 404 ISSN 1350-4487 Altmetric
2017	BrachyView: Combining LDR seed positions with transrectal ultrasound imaging in a prostate gel phantom Published In Physica Medica: an international journal devoted to the applications of physics to medicine and biology Volume 34 Pages 55 - 64 ISSN 1724-191X Altmetric
2017	Characterization of proton pencil beam scanning and passive beam using a high spatial resolution solid-state microdosimeter Published In Medical Physics Volume 44 Pages 6085 - 6095 ISSN 0094-2405 Altmetric
2017	Clinical application of MOSkin dosimeters to rectal wall in vivo dosimetry in gynecological HDR brachytherapy Published In Physica Medica: an international journal devoted to the applications of physics to medicine and biology Volume 41 Pages 5 - 12 ISSN 1724-191X Altmetric
2017	Comparison of phantom materials for use in quality assurance of microbeam radiation therapy Published In Journal of Synchrotron Radiation Volume 24 Pages 866 - 876 ISSN 0909-0495 Altmetric
2017	Correction factors to convert microdosimetry measurements in silicon to tissue in ¹²C ion therapy Published In Physics in Medicine and Biology Volume 62 Pages 2055 - 2069 ISSN 0031-9155 Altmetric
2017	Development of a silicon diode detector for skin dosimetry in radiotherapy Published In Medical Physics Volume 44 Pages 5402 - 5412 ISSN 0094-2405 Altmetric
2017	Effect of scattered electrons on the 'Magic Plate' transmission array detector response Published In Journal of Physics: Conference Series Volume 777 Pages 012033-1 - 012033-4 Altmetric
2017	Experimental studies with two novel silicon detectors for the development of time-of-flight spectrometry of laser-accelerated proton beams Published In Journal of Physics: Conference Series Volume 777 Pages 012018-1 - 012018-4 Altmetric
2017	Feasibility study of a novel multi-strip silicon detector for use in proton therapy range verification quality assurance Published In Radiation Measurements Volume 106 Pages 378 - 384 ISSN 1350-4487 Altmetric
2017	High-resolution fiber-optic dosimeters for microbeam radiation therapy Published In Medical Physics Volume 44 Pages 1965 - 1968 ISSN 0094-2405 Altmetric
2017	Impact of a monolithic silicon detector operating in transmission mode on clinical photon beams Published In Physica Medica: an international journal devoted to the applications of physics to medicine and biology Volume 43 Pages 114 - 119 ISSN 1724-191X Altmetric
2017	In vitro investigation of the dose-rate effect on the biological effectiveness of megavoltage X-ray radiation doses Published In Applied Radiation and Isotopes Volume 128 Pages 114 - 119 ISSN 0969-8043 Altmetric
2017	Initial testing of a pixelated silicon detector prototype in proton therapy Published In Journal of Applied Clinical Medical Physics Volume 18 Pages 315 - 324 ISSN 1526-9914 Altmetric
2017	Innovative detectors for quality assurance dosimetry in SBRT of stationary and movable targets Published In Journal of Physics: Conference Series Volume 777 Pages 012014-1 - 012014-4 Altmetric
2017	Introducing dynamic dosimaging: Potential applications for MRI-linac Published In Journal of Physics: Conference Series Volume 777 Pages 012007-1 - 012007-5 Altmetric
2017	Microdosimetric measurements of a clinical proton beam with micrometer-sized solid-state detector Published In Medical Physics Volume 44 Pages 6029 - 6037 ISSN 0094-2405 Altmetric
2017	Nanostructures, concentrations and energies: an ideal equation to extend therapeutic efficiency on radioresistant 9L tumour cells using Ta2O5 ceramic nanostructured particles Published In Biomedical Physics & Engineering Express Volume 3 Pages 015018-1 - 015018-13 Altmetric
2017	New 3D Silicon detectors for dosimetry in Microbeam Radiation Therapy Published In Journal of Physics: Conference Series Volume 777 Pages 012009-1 - 012009-5 Altmetric
2017	New silicon microdosimetry probes for RBE and biological dose studies using stationary and movable targets in ¹²C ion therapy Published In Journal of Physics: Conference Series Volume 777 Pages 012019-1 - 012019-4 Altmetric
2017	Optimisation of output factor measurements using the Magic Plate 512 silicon dosimeter array in small megavoltage photon fields Published In Journal of Physics: Conference Series Volume 777 Pages 012022-1 - 012022-5 Altmetric
2017	RBE study using solid state microdosimetry in heavy ion therapy Published In Radiation Measurements Volume 106 Pages 512 - 518 ISSN 1350-4487 Altmetric
2017	Radiation response and basic dosimetric characterisation of the 'Magic Plate' Published In Journal of Physics: Conference Series Volume 777 Pages 012034-1 - 012034-4 Altmetric
2017	Study of the correlation between rectal wall in vivo dosimetry performed with MOSkins and implant modification during TRUS-guided HDR prostate brachytherapy Published In Radiation Measurements Volume 106 Pages 385 - 390 ISSN 1350-4487 Altmetric
2017	Synchrotron activation radiotherapy: Effects of dose-rate and energy spectra to tantalum oxide nanoparticles selective tumour cell radiosensitization enhancement Published In Journal of Physics: Conference Series Volume 777 Pages 012011-1 - 012011-4 Altmetric
2017	Technical Note: Angular dependence of a 2D monolithic silicon diode array for small field dosimetry Published In Medical Physics Volume 44 Pages 4313 - 4321 ISSN 0094-2405 Altmetric
2017	The angular dependence of a two dimensional monolithic detector array for dosimetry in small radiation fields Published In Journal of Physics: Conference Series Volume 777 Pages 012020-1 - 012020-4 Altmetric
2017	Thermoluminescence dose response of photon irradiated NaCl: Unified interaction model analysis of the dependence of the supralinearity on photon energy Published In Radiation Measurements Volume 106 Pages 455 - 458 ISSN 1350-4487 Altmetric
2017	X-Tream dosimetry of highly brilliant X-ray microbeams in the MRT hutch of the Australian Synchrotron Published In Radiation Measurements Volume 106 Pages 405 - 411 ISSN 1350-4487 Altmetric
2017	X-ray microbeam measurements with a high resolution scintillator fibre-optic dosimeter Published In Scientific Reports Volume 7 Pages 12450-1 - 12450-7 ISSN 2045-2322 Altmetric
2016	Absorbed dose-to-water protocol applied to synchrotron-generated x-rays at very high dose rates Published In Physics in Medicine and Biology Volume 61 Pages N349 - N361 ISSN 0031-9155 Altmetric
2016	Analytical modelling and simulation of single and double cone pinholes for real-time in-body tracking of an HDR brachytherapy source Published In IEEE Transactions on Nuclear Science Volume 63 Pages 1375 - 1385 ISSN 1558-1578 Altmetric
2016	Beam perturbation characteristics of a 2D transmission silicon diode array, Magic Plate Published In Journal of Applied Clinical Medical Physics Volume 17 Pages 85 - 98 ISSN 1526-9914
2016	BrachyView: multiple seed position reconstruction and comparison with CT post-implant dosimetry Published In Journal of Instrumentation Volume 11 Pages P05002-1 - P05002-16 ISSN 1748-0221 Altmetric
2016	Characterisation of silicon diode arrays for dosimetry in external beam radiation therapy Published In IEEE Transactions on Nuclear Science Volume 63 Pages 1808 - 1817 ISSN 1558-1578 Altmetric
2016	Dose verification of eye plaque brachytherapy using spectroscopic dosimetry Published In Australasian Physical and Engineering Sciences in Medicine Volume 39 Pages 627 - 632 ISSN 0158-9938 Altmetric
2016	First proof of bismuth oxide nanoparticles as efficient radiosensitisers on highly radioresistant cancer cells Published In Physica Medica: an international journal devoted to the applications of physics to medicine and biology Volume 32 Pages 1444 - 1452 ISSN 1724-191X Altmetric
2016	In vivo rectal wall measurements during HDR prostate brachytherapy with MOSkin dosimeters integrated on a trans-rectal US probe: Comparison with planned and reconstructed doses Published In Radiotherapy and Oncology Volume 118 Pages 148 - 153 ISSN 0167-8140 Altmetric
2016	Initial experiments with gel-water: towards MRI-linac dosimetry and imaging Published In Australasian Physical and Engineering Sciences in Medicine Volume 39 Pages 921 - 932 ISSN 0158-9938 Altmetric
2016	Local dose enhancement of proton therapy by ceramic oxide nanoparticles investigated with Geant4 simulations Published In Physica Medica: an international journal devoted to the applications of physics to medicine and biology Volume 32 Pages 1584 - 1593 ISSN 1724-191X Altmetric
2016	Multi-strip silicon sensors for beam array monitoring in micro-beam radiation therapy Published In Physica Medica: an international journal devoted to the applications of physics to medicine and biology Volume 32 Pages 1795 - 1800 ISSN 1724-191X Altmetric
2016	Optimizing dose enhancement with Ta2O5 nanoparticles for synchrotron microbeam activated radiation therapy Published In Physica Medica: an international journal devoted to the applications of physics to medicine and biology Volume 32 Pages 1852 - 1861 ISSN 1724-191X Altmetric
2016	Real-time eye lens dose monitoring during cerebral angiography procedures Published In European Journal of Radiology Volume 26 Pages 79 - 86 ISSN 0720-048X Altmetric
2016	Study of the effect of ceramic TaO₅ nanoparticle distribution on cellular dose enhancement in a kilovoltage photon field Published In Physica Medica: an international journal devoted to the applications of physics to medicine and biology Volume 32 Pages 1216 - 1224 ISSN 1724-191X Altmetric
2016	Synthesis-dependent surface defects and morphology of hematite nanoparticles and their effect on cytotoxicity in vitro Published In ACS Applied Materials and Interfaces Volume 8 Pages 5867 - 5876 ISSN 1944-8244 Altmetric
2016	X-Tream quality assurance in synchrotron X-ray microbeam radiation therapy Published In Journal of Synchrotron Radiation Volume 23 Pages 1180 - 1190 ISSN 0909-0495 Altmetric
2015	MagicPlate-512: a 2D silicon detector array for quality assurance of stereotactic motion adaptive radiotherapy Published In Medical Physics Volume 42 Pages 2992 - 3004 ISSN 0094-2405 Altmetric
2015	2D mapping of the MV photon fluence and 3D dose reconstruction in real time for quality assurance during radiotherapy treatment Published In Journal of Instrumentation Volume 10 Pages 1 - 14 ISSN 1748-0221 Altmetric
2015	3D bridge microdosimeter: Charge collection study and application to RBE studies in 12C radiation therapy Published In Journal and Proceedings of the Royal Society of New South Wales Volume 148 Pages 44 - 51 ISSN 0035-9173
2015	3D-mesa 'bridge' silicon microdosimeter: charge collection study and application to RBE studies in 12C radiation therapy Published In IEEE Transactions on Nuclear Science Volume 62 Pages 504 - 511 ISSN 1558-1578 Altmetric
2015	3d silicon microdosimetry and RBE study using 12C ion of different energies Published In IEEE Transactions on Nuclear Science Volume 62 Pages 3027 - 3033 ISSN 1558-1578 Altmetric
2015	A new virtual ring-based system matrix generator for iterative image reconstruction in high resolution small volume PET systems Published In Physics in Medicine and Biology Volume 60 Pages 6949 - 6973 ISSN 0031-9155 Altmetric

Investigator On

Year	Title
2016 - 2020	3D-BrachyView: a 3D real-time virtual reality intra-operative Quality Assurance system for brachytherapy Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Development Grant
2019	Investigating the impact of detector packaging upon angular and energy dependence of the PTW microdiamond Awarded by: Australian Nuclear Science and Technology Organisation (ANSTO) Funding Scheme: Australian Synchrotron Access Program
2019	Microbeam radiation therapy at 4T: Dosimetric characterisation in preparation for an in-vivo brain cancer treatment study Awarded by: Australian Nuclear Science and Technology Organisation (ANSTO) Funding Scheme: Australian Synchrotron Access Program
2019	What can new developments in X-Tream Dosimetry teach us for the utilization of dose enhancement in experimental microbeam radiotheraphy and clinical radiotherapy? Awarded by: Deutscher Akademischer Austausch Dienst (DAAD) Funding Scheme: Australia Germany Joint Cooperation Scheme
2015 - 2018	Design and application of new nanomaterials theranostic platforms for targeted treatment of cancer Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2015 - 2018	X-RATE: A novel radiation detector platform to realise new opportunities in radiotherapy at the Australian Synchrotron Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Development Grant
2016	Far-Infrared Spectroscopy of Quantum Spin chain: PdCuSO4(HO)2 Awarded by: Australian Synchrotron Company P/L Funding Scheme: Travel Grant
2016	Investigation of the effects of tantalum pentoxide and bismuth oxide nano particles on 9L gilosarcoma and MDCK etc Awarded by: Australian Synchrotron Company P/L Funding Scheme: Travel Grant
2016	Small animal stereotaxic instrument and microinjection unit Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2015 - 2016	New silicon dosimetry probes with an isolated 3D sensitive volume for pre-treatment quality assurance of dynamic microbeam radiation therapy Awarded by: Australian Synchrotron Company P/L Funding Scheme: Travel Grant
2015	Investigation of the effects of tantalum pentoxide and bismuth oxide nano particles on 9L gliosarcoma and MDCK non cancerour cells using both synchrotron generated broad and micro-beams monitored by the X-tream dosimetry system. Awarded by: Australian Synchrotron Research Program Funding Scheme: Travel Grant
2014	Using Nonlinear Effects as a Method for cheap THz Radiation Production Awarded by: Australian Synchrotron Company P/L Funding Scheme: Travel Grant
2013	Innovative methods in radiotherapy and radiosurgery using synchrotron radiation Awarded by: The Research Council of Norway Funding Scheme: European Cooperation in the field of Scientific and Technical Research - COST
2013	Silicon based 3D mini- and microdosometer Awarded by: The Research Council of Norway Funding Scheme: European Cooperation in the field of Scientific and Technical Research - COST
2012	Australian Synchrotron Access Program Awarded by: Australian Research Council (ARC) Funding Scheme: Special Research Initiatives
2012	Improving radiation therapy of static and moving targets using high spatial resolution real-time dosimeters Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2011	Dosimetry in Synchrotron X-Ray Microbeam Radiation Therapy Awarded by: Australian Synchrotron Company P/L Funding Scheme: Travel Grant
2011	Radiosurgery with sub-millimeter x-ray beams: development of the X-Tream real-time beam monitoring and Quality Assurance system Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Development Grant
2010	BrachyVision: A novel multipurpose probe for in-body radiation imaging and dosimetry. Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Development Grant
2010	Development of innovative radiation detectors and computational techniques for improving quality of life Awarded by: Australian Research Council (ARC) Funding Scheme: Discovery Projects
2010	New solid state detectors for real time absolute dosimetry in microbeam radiation therapy Awarded by: European Synchrotron Radiation Facility Funding Scheme: Beam Time
2010	New solid state detectors for real time absolute dosimetry in microbeam radiation therapy Awarded by: Australian Synchrotron Research Program Funding Scheme: Travel Grant
2009	Development of a real time multichannel radiation dosimetry system for Microbeam Radiation Therapy (MRT) quality assurance and further studies in magneto-MRT Awarded by: Australian Synchrotron Research Program Funding Scheme: Travel Grant
2009	High spatial resolution dosimetry for radioactive plaques used for radiotherapy of eye lesions Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2008	Characterisation of innovative Si radiation detectors for high spatial resolution isotopic imaging Awarded by: Australian Institute of Nuclear Science and Engineering (AINSE) Funding Scheme: Research Award
2008	IBIC studies of detectors for synchrotron X-ray dosimetry Awarded by: Australian Institute of Nuclear Science and Engineering (AINSE) Funding Scheme: Research Award
2007	IBIC studies of detectors for synchrotron X-ray dosimetry Awarded by: Australian Institute of Nuclear Science and Engineering (AINSE) Funding Scheme: Grant
2007	Magnetic-Field Enhancement Radiotherapy - A new concept in Cancer treatment Awarded by: Cancer Institute NSW Funding Scheme: Research Innovation Grants
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	Comparison and evaluation of alternate dosimeter technologies for MRT Awarded by: Australian Synchrotron Company P/L Funding Scheme: Travel Grant
	Development of radiation detectors to better understand ion interactions Awarded by: Australian Research Council (ARC) Funding Scheme: Discovery Projects
	Enhancing synchrotron microbeam radiation therapy in vivo with high-Z nanoparticles Awarded by: Australian Synchrotron Research Program Funding Scheme: Imaging and Medical Beamline
	Fast and efficient assessment of dose in small targets in radiotherapy: Effect of motion in clinical research and implementation of dynamic therapy Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
	Investigation of the effects of thulium oxide nanoparticles and anti-cancer drugs on tumorous 9L gliosarcoma and MDCK non cancerous cells using micro-beams monitored by the X-tream dosimetry system Awarded by: Australian Synchrotron Company P/L Funding Scheme: Travel Grant
	Investigation of the effects of thulium oxide nanoparticles and anti-cancer drugs on tumorous 9L gliosarcoma and MDCK non cancerous cells using micro-beams monitored by the x-tream dosimetry system and characterisation of DNA damage-repair with yH2AX Awarded by: Australian Synchrotron Research Program Funding Scheme: Beamtime at the AS XAS Beamline
	Low temperature THz spectroscopy of artists pigments Awarded by: Australian Synchrotron Company P/L Funding Scheme: Travel Grant
	Radiotheraphy 'dry-run' as feasibility study for veterinary trials in hutch 3B Awarded by: Australian Synchrotron Research Program Funding Scheme: Imaging and Medical Beamline
	Refining synchrotron microbeam radiation therapy techniques in vivo Awarded by: Australian Nuclear Science and Technology Organisation (ANSTO) Funding Scheme: Australian Synchrotron Access Program
	Silicon on diamond strip detectors for MRT Awarded by: Australian Synchrotron Company P/L Funding Scheme: Travel Grant
	Transmission detectors for real time beam monitoring Awarded by: Australian Synchrotron Research Program Funding Scheme: Imaging and Medical Beamline

Impact Story

Advisees

Graduate Advising Relationship

Degree	Research Title	Advisee
Doctor of Philosophy	Microbeam Radiation Therapy: Development of Instrumentation and Software Tools for Quality Assurance	Cameron, Matthew
Doctor of Philosophy	Development of a silicon-on-diamond dosimeter for Microbeam Radiation Therapy	Dipuglia, Andrew
Doctor of Philosophy	Advance Nanocomposites for health protection applications	Mueen, Rafid Abdlateef
Doctor of Philosophy	Assessing MRI-linac based Radiotherapy Uncertainties	Roberts, Natalia
Master of Philosophy	Single-Molecule Studies of Exonuclease Proteins	Muir, Ryan
Doctor of Philosophy	Lanthanide nanoparticles for image guided multimodal therapies	Engels, Elette
Doctor of Philosophy (Integrated)	Multimodal Therapy: A Combination of Oncothermia, Microbeam Radiation Therapy and Nano Therapy	Hollis, Carolyn
Master of Research - EIS	Synthesis and characterisation of barium-doped lanthanum manganite nanoparticles	O'Keefe, Alice
Doctor of Philosophy	Development and Experimental Validation of a Monte Carlo Based Treatment Planning System for Microbeam Radiation Therapy	Paino, Jason
Doctor of Philosophy	'Enhancement of Radiation Therapies Using High-Z Nanoparticles and Drugs'	Valceski, Michael
Doctor of Philosophy	Investigation into the Use of Lanthanide Metal Oxide Nanoparticles for the Theranostic Treatment of Cancer	Vogel, Sarah
Master of Philosophy - EIS	Nature of collapse induced radiation (Pre-Hawking radiation) generated by the excitation of fields in the spacetime during the process of gravitational collapse of a Schwarzschild black hole	Shrestha, Ankit

Keywords

semiconductors, radiation dosimetry, radiation therapy, solid state dosimetry, medical physics, microbeam

Located In Facility

Building 4, Room G62

Orcid Id

http://orcid.org/0000-0002-2406-9972 (confirmed)

Scopus Id

7101988713

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Available as Research Supervisor

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Overview

Top Publications

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Publications

Selected Publications

Journal Article

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Impact Story

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Advisees

Graduate Advising Relationship

Background

Keywords

Contact

Located In Facility

Identity

Orcid Id

Scopus Id

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