Engel, Martin

Engel, Martin Dr.

Associate Research Fellow

Centre for Medical and Molecular Bioscience

Faculty of Science, Medicine and Health

School of Biological Sciences

Overview

Year	Title
2015	Neuregulin 1 prevents phencyclidine-induced behavioral impairments and disruptions to GABAergic signaling in mice Published in International Journal of Neuropsychopharmacology

Year

Title

2015

Neuregulin 1 prevents phencyclidine-induced behavioral impairments and disruptions to GABAergic signaling in mice
Published in International Journal of Neuropsychopharmacology

Affiliation

Available for Collaborative Projects

Member Of

Australian Society for Medical Research Chair, New South Wales Branch 2014 -

Publications

Selected Publications

Journal Article

Year	Title
2022	Enabling high throughput drug discovery in 3D cell cultures through a novel bioprinting workflow Published In SLAS technology
2021	Advanced spheroid, tumouroid and 3d bioprinted in-vitro models of adult and paediatric glioblastoma Published In International Journal of Molecular Sciences
2021	Generation and analysis of 3D cell culture models for drug discovery Published In European Journal of Pharmaceutical Sciences
2020	DC and AC magnetic fields increase neurite outgrowth of SH-SY5Y neuroblastoma cells with and without retinoic acid Published In RSC Advances: an international journal to further the chemical sciences
2020	Generation and characterization of a human induced pluripotent stem cell line UOWi005-A from dermal fibroblasts derived from a CCNF^S621G familial amyotrophic lateral sclerosis patient using mRNA reprogramming Published In Stem Cell Research
2020	Novel dual-action prodrug triggers apoptosis in glioblastoma cells by releasing a glutathione quencher and lysine-specific histone demethylase 1A inhibitor Published In Journal of Neurochemistry
2020	The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron Differentiation Published In Cells
2020	A Simple Differentiation Protocol for Generation of Induced Pluripotent Stem Cell-Derived Basal Forebrain-Like Cholinergic Neurons for Alzheimer's Disease and Frontotemporal Dementia Disease Modeling Published In Cells
2020	A Simple Differentiation Protocol for Generation of Induced Pluripotent Stem Cell-derived Basal Forebrain Cholinergic Neurons for Alzheimer¿s Disease and Frontotemporal Dementia Disease Modeling
2020	Identification of repurposable cytoprotective drugs in vanishing white matter disease patient-derived cells Published In Translational Medicine Communications
2020	If Human Brain Organoids Are the Answer to Understanding Dementia, What Are the Questions? Published In Neuroscientist
2020	The mRNA-based reprogramming of fibroblasts from a SOD1^E101G familial amyotrophic lateral sclerosis patient to induced pluripotent stem cell line UOWi007 Published In Stem Cell Research
2019	DC and AC magnetic fields increase neurite outgrowth of SH-SY5Y neuroblastoma cells with and without retinoic acid Published In RSC Advances: an international journal to further the chemical sciences
2019	Generation and characterization of a human induced pluripotent stem cell line UOWi005-A from dermal fibroblasts derived from a CCNF^S621G familial amyotrophic lateral sclerosis patient using mRNA reprogramming Published In Stem Cell Research
2019	Novel dual-action prodrug triggers apoptosis in glioblastoma cells by releasing a glutathione quencher and lysine-specific histone demethylase 1A inhibitor Published In Journal of Neurochemistry
2019	The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron Differentiation Published In Cells
2018	Generation and characterization of human induced pluripotent stem cell lines from a familial Alzheimer's disease PSEN1 A246E patient and a non-demented family member bearing wild-type PSEN1 Published In Stem Cell Research
2018	Liraglutide prevents metabolic side-effects and improves recognition and working memory during antipsychotic treatment in rats Published In Journal of Psychopharmacology
2018	Viral-free generation and characterization of a human induced pluripotent stem cell line from dermal fibroblasts Published In Stem Cell Research
2017	Translationally controlled tumour protein TCTP is induced early in human colorectal tumours and contributes to the resistance of HCT116 colon cancer cells to 5-FU and oxaliplatin Published In Cell Communication and Signaling
2016	Common pitfalls of stem cell differentiation: a guide to improving protocols for neurodegenerative disease models and research Published In Cellular and Molecular Life Sciences
2016	Effect of a glucagon-like peptide 1 (GLP-1) receptor agonist, liraglutide, on cognition and body weight during antipsychotic treatment Published In International Journal of Neuropsychopharmacology
2016	Erratum to: MGluR2/3 agonist LY379268 rescues NMDA and GABAA receptor level deficits induced in a two-hit mouse model of schizophrenia Published In Psychopharmacology
2016	Molecular evidence of synaptic pathology in CA1 in schizophrenia Published In Biological Psychiatry
2016	Molecular evidence of synaptic pathology in the CA1 region in schizophrenia Published In NPJ Schizophrenia
2016	Neuroprotective effects of apigenin against inflammation, neuronal excitability and apoptosis in an induced pluripotent stem cell model of Alzheimer’s disease Published In Scientific Reports
2016	Unmasking the true identity in neuron differentiation Published In Journal of Neuroscience Methods
2016	mGluR2/3 agonist LY379268 rescues NMDA and GABAA receptor level deficits induced in a two-hit mouse model of schizophrenia Published In Psychopharmacology
2015	Alterations of mGluR5 and its endogenous regulators Norbin, Tamalin and Preso1 in schizophrenia: towards a model of mGluR5 dysregulation Published In Acta Neuropathologica
2015	Growth-factor dependent expression of the translationally controlled tumour protein TCTP is regulated through the PI3-K/Akt/mTORC1 signalling pathway Published In Cellular Signalling
2015	Metabotropic glutamate receptor 5, and its trafficking molecules Norbin and Tamalin, are increased in the CA1 hippocampal region of subjects with schizophrenia Published In Schizophrenia Research
2015	Neuregulin 1 prevents phencyclidine-induced behavioral impairments and disruptions to GABAergic signaling in mice Published In International Journal of Neuropsychopharmacology
2014	Negativity towards negative results: a discussion of the disconnect between scientific worth and scientific culture Published In Disease Models and Mechanisms
2014	Positives in negative results: when finding ‘nothing’ means something Published In The Conversation
2013	Neuregulin-1 signalling and antipsychotic treatment: potential therapeutic targets in a schizophrenia candidate signalling pathway Published In Psychopharmacology

Conference Paper

Year	Title
2015	TCTP is induced early in colorectal cancer, it is translationally regulated via the Akt/mTORC1 pathway, and it contributes to the resistance of HCT116 colon cancer cells to 5-FU and oxaliplatin Published In FEBS JOURNAL
2014	Alterations of mGluR5 and mGluR5 signaling partners in schizophrenia Published In Abstracts for 2014 Society for Neuroscience Annual Meeting
2013	Quantitation of neurotransmitters and metabolites in microdialysate fluid and brain using advanced gas chromatographymass spectrometry (GC-MS) Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants

Contact

Full Name

Martin Engel

Mailing Address

IHMRI

University of Wollongong

Wollongong

Select State

2522

Australia