Green, Katrina (Weston-Green)

Overview

Dr Katrina Green (Weston-Green) is a neuropharmacologist and Senior Lecturer in the School of Medicine, University of Wollongong, Australia. Her research aims to improve the pharmacological treatment of brain illness.
Examples of current projects include:

Investigating the medicinal potential of phytochemicals in the cannabis plant (which contains +600 compounds) to improve brain function (eg treat deficits in learning and memory, depression, anxiety, psychosis)
Improving cognition and vascular function through bioactive plant-based compounds, flavonoids and anthocyanins (abundant in plums, cherries and blueberries)
Investigating the role of gut bacteria (microbiota) and cognitive function in mental illness (psychosis, depression, anxiety and substance abuse disorders)
Preventing obesity and diabetes side-effects of antipsychotic treatment and improving cognitive function using a protein originally discovered in the saliva of the world's only venomous lizard, the Glia monster

Dr Green is passionate about bridging the gap between medical science and industry (eg horticulture and pharmaceutical) to develop the best medicines that translate to improved health outcomes.

Top Publications

Year	Title
2017	A systematic review of the effect of cannabidiol on cognitive function: Relevance to schizophrenia Published in Neuroscience and Biobehavioral Reviews
2017	Improved social interaction, recognition and working memory with cannabidiol treatment in a prenatal infection (poly I:C) rat model Published in Neuropsychopharmacology
2016	Effect of a glucagon-like peptide 1 (GLP-1) receptor agonist, liraglutide, on cognition and body weight during antipsychotic treatment Published in International Journal of Neuropsychopharmacology
2019	Alterations to the microbiota–colon–brain axis in high-fat-diet-induced obese mice compared to diet-resistant mice Published in Journal of Nutritional Biochemistry
2017	The effects of maternal antidepressant use on offspring behaviour and brain development: Implications for risk of neurodevelopmental disorders Published in Neuroscience and Biobehavioral Reviews

Research Areas

Available as Research Supervisor

Selected Publications

Journal Article

Year	Title
2019	Alterations to the microbiota–colon–brain axis in high-fat-diet-induced obese mice compared to diet-resistant mice Published In Journal of Nutritional Biochemistry Volume 65 Pages 54 - 65 ISSN 0955-2863 Altmetric
2019	Perinatal exposure to fluoxetine increases anxiety- and depressive-like behaviours and alters glutamatergic markers in the prefrontal cortex and hippocampus of male adolescent rats: A comparison between Sprague-Dawley rats and the Wistar-Kyoto rat model of depression Published In Journal of Psychopharmacology Volume 33 Pages 230 - 243 ISSN 1461-7285 Altmetric
2018	Could an allied health care approach reduce the unacceptable incidence of suicide after psychiatric hospital discharge? Published In Bipolar Disorders: an international journal of psychiatry and neurosciences Volume 20 Pages 403 - 404 ISSN 1398-5647 Altmetric
2018	Decreased 5‐HT2cR and GHSR1a interaction in antipsychotic drug‐induced obesity Published In Obesity Reviews Volume 19 Pages 396 - 405 ISSN 1467-7881 Altmetric
2018	Dietary Galacto-Oligosaccharides and Resistant Starch Protect Against Altered CB1 and 5-HT1A and 2A Receptor Densities in Rat Brain: Implications for Preventing Cognitive and Appetite Dysfunction During a High-Fat Diet Published In Molecular Nutrition and Food Research Volume Online First Pages 1800422-1 - 1800422-9 ISSN 1613-4133 Altmetric
2018	Disrupted sphingolipid metabolism following acute clozapine and olanzapine administration Published In British Journal of Biomedical Science Volume 25 Pages 40-1 - 40-11 ISSN 0967-4845 Altmetric
2018	Liraglutide prevents metabolic side-effects and improves recognition and working memory during antipsychotic treatment in rats Published In Journal of Psychopharmacology Volume 32 Pages 578 - 590 ISSN 1461-7285 Altmetric
2017	A systematic review of the effect of cannabidiol on cognitive function: Relevance to schizophrenia Published In Neuroscience and Biobehavioral Reviews Volume 72 Pages 310 - 324 ISSN 0149-7634 Altmetric
2017	Improved social interaction, recognition and working memory with cannabidiol treatment in a prenatal infection (poly I:C) rat model Published In Neuropsychopharmacology Volume 42 Pages 1447 - 1457 ISSN 0893-133X Altmetric
2017	The effects of maternal antidepressant use on offspring behaviour and brain development: Implications for risk of neurodevelopmental disorders Published In Neuroscience and Biobehavioral Reviews Volume 80 Pages 743 - 765 ISSN 0149-7634 Altmetric
2016	A method of providing engaging formative feedback to large cohort first-year physiology and anatomy students Published In Advances in Physiology Education Volume 40 Pages 393 - 397 ISSN 1043-4046 Altmetric
2016	Effect of a glucagon-like peptide 1 (GLP-1) receptor agonist, liraglutide, on cognition and body weight during antipsychotic treatment Published In International Journal of Neuropsychopharmacology Volume 19 Pages 55 - 55 ISSN 1461-1457 Altmetric
2016	Effect of cannabidiol on cognition in a maternal immune activation (poly IC) model of schizophrenia Published In International Journal of Neuropsychopharmacology Volume 19 Pages 183 - 183 ISSN 1461-1457 Altmetric
2013	Second generation antipsychotic-induced type 2 diabetes: a role for the muscarinic M3 receptor Published In CNS Drugs Volume 27 Pages 1069 - 1080 ISSN 1172-7047 Altmetric
2012	Alterations to melanocortinergic, GABAergic and cannabinoid neurotransmission associated with olanzapine-induced weight gain Published In PLoS One Volume 7 Pages e33548 - 1 - e33548 - 12 ISSN 1932-6203 Altmetric
2012	Effects of olanzapine on muscarinic M3 receptor binding density in the brain relates to weight gain, plasma insulin and metabolic hormone levels Published In European Neuropsychopharmacology Volume 22 Pages 364 - 373 ISSN 0924-977X Altmetric
2011	Olanzapine treatment and metabolic dysfunction: a dose response study in female Sprague Dawley rats Published In Behavioural Brain Research Volume 217 Pages 337 - 346 ISSN 0166-4328 Altmetric
2010	Olanzapine decreases POMC MRNA expression and M3 receptors binding density in the hypothalamus and brainstem: pathway for weight gain side-effect? Published In Australian and New Zealand Journal of Psychiatry Volume 44 Page p. A55 ISSN 0004-8674
2010	Olanzapine decreases cannabinoid CB1 receptors in the hypothalamus and brainstem, possibly through muscarinic M3 receptor antagonism Published In International Journal of Neuropsychopharmacology Volume 13 Pages 111 - 112 ISSN 1461-1457 Altmetric
2010	Sensitivity of the female rat to olanzapine-induced weight gain - far from the clinic? Published In Schizophrenia Research Volume 116 Pages 299 - 300 ISSN 1573-2509 Altmetric
2010	The role of histaminergic H1 and H3 receptors in food intake:-A mechanism fo atypical antipsychotic-induced weight gain? Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 34 Pages 1 - 4 ISSN 0364-7722 Altmetric
2008	The effects of antipsychotics on the density of cannabinoid receptors in the dorsal vagal complex of rats: Implications for olanzapine-induced weight gain Published In International Journal of Neuropsychopharmacology Volume 11 Pages 827 - 835 ISSN 1461-1457 Altmetric
2007	Dose-dependent effects of atypical antipsychotic drug olanzapine on weight gain and cholecystokinin levels in rats Published In Neuroscience Bulletin Volume 23 Pages 352 - 352 ISSN 1673-7067
2007	Olanzapine treatment decreases the density of muscarinic M2 receptors in the dorsal vagal complex of rats Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 31 Pages 915 - 920 ISSN 0364-7722 Altmetric

Conference Paper

Year	Title
2013	Binding affinity of aripiprazole to the dopamine D2 receptor in different regions of the rat brain Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants Pages 115 - 115
2012	Differential effects of aripiprazole and haloperidol on dopamine markers in the arcuate nucleus and prolactin levels in male rats Published In The International Journal of Neuropsychopharmacology: Abstracts from the 28th CINP World Congress of Neuropsychopharmacology Pages 60 - 60 Altmetric
2011	Neuroendocrinological regulation of insulin dysfunction induced by olanzapine Published In 31st Annual Meeting of the Australian Neuroscience Society Pages 54 - 54
2010	Olanzapine decreases [3H]SR141716A binding to cannabinoid CB1 receptors in the rat hippocampus and auditory cortex: a dosage-dependent response Published In Australian Neuroscience Society Annual Meeting, Sydney 2010 Page p. 82
2010	Olanzapine-induced metabolic dysfunction: a role for central muscarinic M3 receptors Published In Australian Neuroscience Society Annual Meeting, Sydney 2010 Page p. 33
2010	The dosage response to the side-effect of metabolic dysfunction in female rats following olanzapine treatment Published In Australian Neuroscience Society Annual Meeting, Sydney 2010 Page p. 82
2007	Effects of antipsychotic drugs on weight gain and CB1 receptors in the dorsal vagal complex of rats Published In 7th IBRO World Congress of Neuroscience Page p. 144

Investigator On

Year	Title
2019 - 2021	The United Colours of Cannabis: A novel approach to treating the cognitive symptoms of schizophrenia Awarded by: Rebecca L Cooper Medical Research Foundation Funding Scheme: Medical Research Project Grant
2018	Forced exercise/walking wheel system for rats Model 80805A Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2015 - 2016	Improving pharmacological treatment of Schizophrenia: Focus on cognition and metabolic side-effects Awarded by: Schizophrenia Fellowship of NSW Funding Scheme: Peter Meyer Fund
2014	SR-LAB ABS System Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant

Available as Research Supervisor

Potential Supervision Topics

Dr Green's research aims to discover new pharmacological treatments for illnesses of the brain where existing medications are lacking in efficacy. Examples of topics for potential Higher Degree Research students include (not limited to):
- Examining effects of phytochemicals derived from natural sources (eg cannabis / hemp, fruits / berries) on the brain and behaviour (and the underlying mechanisms of benefits/harms)
- Investigating the role of gut microbiota on brain function / illness (and underlying mechanisms)
- Understanding the pathogenesis of cognitive dysfunction during brain illness
Preclinical (cell and rodent models) and clinical research programs available.

Advisees

Graduate Advising Relationship

Degree	Research Title	Advisee
Doctor of Philosophy	Improving the treatment of Schizophrenia by addressing cognitive impairment and the metabolic side-effects of antipsychotic drugs
Doctor of Philosophy	To CBD or Not to CBD? Understanding the Therapeutic Potential of Cannabidiol, a Component of Cannabis, for Schizophrenia	Osborne, Ashleigh
Doctor of Philosophy	The Effects of Maternal Fluoxetine Treatment on Offspring Brain Development and Behaviour	Millard, Samuel
Doctor of Philosophy	Probiotics and Gut Health	Rosario, Vinicius
Doctor of Philosophy	Efficacy Investigation of Terpenes and Cannabidiol in a Rodent Model of Depression	Clunas, Helen

Orcid Id

http://orcid.org/0000-0002-4521-8463 (confirmed)

Scopus Id

16243089800

Top Publications

Year	Title
2017	A systematic review of the effect of cannabidiol on cognitive function: Relevance to schizophrenia Published in Neuroscience and Biobehavioral Reviews
2017	Improved social interaction, recognition and working memory with cannabidiol treatment in a prenatal infection (poly I:C) rat model Published in Neuropsychopharmacology
2016	Effect of a glucagon-like peptide 1 (GLP-1) receptor agonist, liraglutide, on cognition and body weight during antipsychotic treatment Published in International Journal of Neuropsychopharmacology
2019	Alterations to the microbiota–colon–brain axis in high-fat-diet-induced obese mice compared to diet-resistant mice Published in Journal of Nutritional Biochemistry
2017	The effects of maternal antidepressant use on offspring behaviour and brain development: Implications for risk of neurodevelopmental disorders Published in Neuroscience and Biobehavioral Reviews

Research Areas

Selected Publications

Journal Article

Year	Title
2019	Alterations to the microbiota–colon–brain axis in high-fat-diet-induced obese mice compared to diet-resistant mice Published In Journal of Nutritional Biochemistry Volume 65 Pages 54 - 65 ISSN 0955-2863 Altmetric
2019	Perinatal exposure to fluoxetine increases anxiety- and depressive-like behaviours and alters glutamatergic markers in the prefrontal cortex and hippocampus of male adolescent rats: A comparison between Sprague-Dawley rats and the Wistar-Kyoto rat model of depression Published In Journal of Psychopharmacology Volume 33 Pages 230 - 243 ISSN 1461-7285 Altmetric
2018	Could an allied health care approach reduce the unacceptable incidence of suicide after psychiatric hospital discharge? Published In Bipolar Disorders: an international journal of psychiatry and neurosciences Volume 20 Pages 403 - 404 ISSN 1398-5647 Altmetric
2018	Decreased 5‐HT2cR and GHSR1a interaction in antipsychotic drug‐induced obesity Published In Obesity Reviews Volume 19 Pages 396 - 405 ISSN 1467-7881 Altmetric
2018	Dietary Galacto-Oligosaccharides and Resistant Starch Protect Against Altered CB1 and 5-HT1A and 2A Receptor Densities in Rat Brain: Implications for Preventing Cognitive and Appetite Dysfunction During a High-Fat Diet Published In Molecular Nutrition and Food Research Volume Online First Pages 1800422-1 - 1800422-9 ISSN 1613-4133 Altmetric
2018	Disrupted sphingolipid metabolism following acute clozapine and olanzapine administration Published In British Journal of Biomedical Science Volume 25 Pages 40-1 - 40-11 ISSN 0967-4845 Altmetric
2018	Liraglutide prevents metabolic side-effects and improves recognition and working memory during antipsychotic treatment in rats Published In Journal of Psychopharmacology Volume 32 Pages 578 - 590 ISSN 1461-7285 Altmetric
2017	A systematic review of the effect of cannabidiol on cognitive function: Relevance to schizophrenia Published In Neuroscience and Biobehavioral Reviews Volume 72 Pages 310 - 324 ISSN 0149-7634 Altmetric
2017	Improved social interaction, recognition and working memory with cannabidiol treatment in a prenatal infection (poly I:C) rat model Published In Neuropsychopharmacology Volume 42 Pages 1447 - 1457 ISSN 0893-133X Altmetric
2017	The effects of maternal antidepressant use on offspring behaviour and brain development: Implications for risk of neurodevelopmental disorders Published In Neuroscience and Biobehavioral Reviews Volume 80 Pages 743 - 765 ISSN 0149-7634 Altmetric
2016	A method of providing engaging formative feedback to large cohort first-year physiology and anatomy students Published In Advances in Physiology Education Volume 40 Pages 393 - 397 ISSN 1043-4046 Altmetric
2016	Effect of a glucagon-like peptide 1 (GLP-1) receptor agonist, liraglutide, on cognition and body weight during antipsychotic treatment Published In International Journal of Neuropsychopharmacology Volume 19 Pages 55 - 55 ISSN 1461-1457 Altmetric
2016	Effect of cannabidiol on cognition in a maternal immune activation (poly IC) model of schizophrenia Published In International Journal of Neuropsychopharmacology Volume 19 Pages 183 - 183 ISSN 1461-1457 Altmetric
2013	Second generation antipsychotic-induced type 2 diabetes: a role for the muscarinic M3 receptor Published In CNS Drugs Volume 27 Pages 1069 - 1080 ISSN 1172-7047 Altmetric
2012	Alterations to melanocortinergic, GABAergic and cannabinoid neurotransmission associated with olanzapine-induced weight gain Published In PLoS One Volume 7 Pages e33548 - 1 - e33548 - 12 ISSN 1932-6203 Altmetric
2012	Effects of olanzapine on muscarinic M3 receptor binding density in the brain relates to weight gain, plasma insulin and metabolic hormone levels Published In European Neuropsychopharmacology Volume 22 Pages 364 - 373 ISSN 0924-977X Altmetric
2011	Olanzapine treatment and metabolic dysfunction: a dose response study in female Sprague Dawley rats Published In Behavioural Brain Research Volume 217 Pages 337 - 346 ISSN 0166-4328 Altmetric
2010	Olanzapine decreases POMC MRNA expression and M3 receptors binding density in the hypothalamus and brainstem: pathway for weight gain side-effect? Published In Australian and New Zealand Journal of Psychiatry Volume 44 Page p. A55 ISSN 0004-8674
2010	Olanzapine decreases cannabinoid CB1 receptors in the hypothalamus and brainstem, possibly through muscarinic M3 receptor antagonism Published In International Journal of Neuropsychopharmacology Volume 13 Pages 111 - 112 ISSN 1461-1457 Altmetric
2010	Sensitivity of the female rat to olanzapine-induced weight gain - far from the clinic? Published In Schizophrenia Research Volume 116 Pages 299 - 300 ISSN 1573-2509 Altmetric
2010	The role of histaminergic H1 and H3 receptors in food intake:-A mechanism fo atypical antipsychotic-induced weight gain? Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 34 Pages 1 - 4 ISSN 0364-7722 Altmetric
2008	The effects of antipsychotics on the density of cannabinoid receptors in the dorsal vagal complex of rats: Implications for olanzapine-induced weight gain Published In International Journal of Neuropsychopharmacology Volume 11 Pages 827 - 835 ISSN 1461-1457 Altmetric
2007	Dose-dependent effects of atypical antipsychotic drug olanzapine on weight gain and cholecystokinin levels in rats Published In Neuroscience Bulletin Volume 23 Pages 352 - 352 ISSN 1673-7067
2007	Olanzapine treatment decreases the density of muscarinic M2 receptors in the dorsal vagal complex of rats Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 31 Pages 915 - 920 ISSN 0364-7722 Altmetric

Conference Paper

Year	Title
2013	Binding affinity of aripiprazole to the dopamine D2 receptor in different regions of the rat brain Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants Pages 115 - 115
2012	Differential effects of aripiprazole and haloperidol on dopamine markers in the arcuate nucleus and prolactin levels in male rats Published In The International Journal of Neuropsychopharmacology: Abstracts from the 28th CINP World Congress of Neuropsychopharmacology Pages 60 - 60 Altmetric
2011	Neuroendocrinological regulation of insulin dysfunction induced by olanzapine Published In 31st Annual Meeting of the Australian Neuroscience Society Pages 54 - 54
2010	Olanzapine decreases [3H]SR141716A binding to cannabinoid CB1 receptors in the rat hippocampus and auditory cortex: a dosage-dependent response Published In Australian Neuroscience Society Annual Meeting, Sydney 2010 Page p. 82
2010	Olanzapine-induced metabolic dysfunction: a role for central muscarinic M3 receptors Published In Australian Neuroscience Society Annual Meeting, Sydney 2010 Page p. 33
2010	The dosage response to the side-effect of metabolic dysfunction in female rats following olanzapine treatment Published In Australian Neuroscience Society Annual Meeting, Sydney 2010 Page p. 82
2007	Effects of antipsychotic drugs on weight gain and CB1 receptors in the dorsal vagal complex of rats Published In 7th IBRO World Congress of Neuroscience Page p. 144

Investigator On

Year	Title
2019 - 2021	The United Colours of Cannabis: A novel approach to treating the cognitive symptoms of schizophrenia Awarded by: Rebecca L Cooper Medical Research Foundation Funding Scheme: Medical Research Project Grant
2018	Forced exercise/walking wheel system for rats Model 80805A Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2015 - 2016	Improving pharmacological treatment of Schizophrenia: Focus on cognition and metabolic side-effects Awarded by: Schizophrenia Fellowship of NSW Funding Scheme: Peter Meyer Fund
2014	SR-LAB ABS System Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant

Potential Supervision Topics

Dr Green's research aims to discover new pharmacological treatments for illnesses of the brain where existing medications are lacking in efficacy. Examples of topics for potential Higher Degree Research students include (not limited to):
- Examining effects of phytochemicals derived from natural sources (eg cannabis / hemp, fruits / berries) on the brain and behaviour (and the underlying mechanisms of benefits/harms)
- Investigating the role of gut microbiota on brain function / illness (and underlying mechanisms)
- Understanding the pathogenesis of cognitive dysfunction during brain illness
Preclinical (cell and rodent models) and clinical research programs available.

Advisees

Graduate Advising Relationship

Degree	Research Title	Advisee
Doctor of Philosophy	Improving the treatment of Schizophrenia by addressing cognitive impairment and the metabolic side-effects of antipsychotic drugs
Doctor of Philosophy	To CBD or Not to CBD? Understanding the Therapeutic Potential of Cannabidiol, a Component of Cannabis, for Schizophrenia	Osborne, Ashleigh
Doctor of Philosophy	The Effects of Maternal Fluoxetine Treatment on Offspring Brain Development and Behaviour	Millard, Samuel
Doctor of Philosophy	Probiotics and Gut Health	Rosario, Vinicius
Doctor of Philosophy	Efficacy Investigation of Terpenes and Cannabidiol in a Rodent Model of Depression	Clunas, Helen

Orcid Id

http://orcid.org/0000-0002-4521-8463 (confirmed)

Scopus Id

16243089800

Green, Katrina (Weston-Green) Dr

Senior Lecturer

Overview

Overview

Top Publications

Research Areas

Available as Research Supervisor

Publications

Selected Publications

Journal Article

Conference Paper

Funding

Investigator On

Supervision

Available as Research Supervisor

Potential Supervision Topics

Advisees

Graduate Advising Relationship

Identity

Orcid Id

Scopus Id

Overview

Top Publications

Research Areas

Publications

Selected Publications

Journal Article

Conference Paper

Funding

Investigator On

Supervision

Potential Supervision Topics

Advisees

Graduate Advising Relationship

Identity

Orcid Id

Scopus Id

Visualisations

Research Areas