Green, Katrina Dr

Head Of

• Neuropharmacology and Molecular Psychiatry Co-Head 2016 -

Member Of

• Australian Centre for Cannabinoid Clinical and Research Excellence Capacity Building Committee Deputy Chair 2018 -
• Molecular Horizons Executive Committee 2018 -
• Academic Senate - UOW SMAH Faculty Representative 2017 -
• Australian Centre for Cannabinoid Clinical and Research Excellence (ACRE), A National Health and Medical Research Council Centre of Research Excellence Scientific Affiliate (Associate Investigator): Preclinical and Clinical Studies of Medicinal Cannabinoids panel 2017 -
• Collegium Internationale Neuro-Psychopharmacologicum (CINP) Member 2017 -
• Illawarra Shoalhaven Local Health District Honorary Research Associate 2017 -
• Medicinal Cannabis Council Australia Member 2017 -
• Biological Psychiatry Australia Member, Senior Mentor to ECR Network Committee 2013 -
• Neuroendocrinology, (Karger, Switzerland) Member of Editorial Board 2013 -
• Illawarra Health and Medical Research Institute Scientific Affiliate 2008 -

Clinical Activities

• Investigating the link between gut microbiota and cognitive function in psychiatric illness and substance abuse Lead Researcher 2017 -

Selected Publications

• Journal Article

  Year	Title
  2022	Cannabidiol induces autophagy and improves neuronal health associated with SIRT1 mediated longevity Published In GeroScience
  2021	A Review of the Potential Use of Pinene and Linalool as Terpene-Based Medicines for Brain Health: Discovering Novel Therapeutics in the Flavours and Fragrances of Cannabis Published In Frontiers in Psychiatry
  2021	Anthocyanins attenuate vascular and inflammatory responses to a high fat high energy meal challenge in overweight older adults: A cross-over, randomized, double-blind clinical trial Published In Clinical Nutrition
  2021	Association between flavonoid intake and risk of hypertension in two cohorts of Australian women: a longitudinal study Published In European Journal of Nutrition
  2021	Cannabidiol regulates CB1-pSTAT3 signaling for neurite outgrowth, prolongs lifespan, and improves health span in Caenorhabditis elegans of Aß pathology models Published In FASEB Journal
  2021	Effect of liraglutide on neural and peripheral markers of metabolic function during antipsychotic treatment in rats Published In Journal of Psychopharmacology
  2021	Food anthocyanins decrease concentrations of TNF-a in older adults with mild cognitive impairment: A randomized, controlled, double blind clinical trial Published In Nutrition, Metabolism and Cardiovascular Diseases
  2021	The effects of perinatal fluoxetine exposure on emotionality behaviours and cortical and hippocampal glutamatergic receptors in female Sprague-Dawley and Wistar-Kyoto rats Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
  2020	Alterations to the microbiota–colon–brain axis in high-fat-diet-induced obese mice compared to diet-resistant mice Published In Journal of Nutritional Biochemistry
  2020	Cannabidiol improves behavioural and neurochemical deficits in adult female offspring of the maternal immune activation (poly I:C) model of neurodevelopmental disorders Published In Brain, Behavior, and Immunity
  2020	Effect of cannabidiol on endocannabinoid, glutamatergic and GABAergic signalling markers in male offspring of a maternal immune activation (poly I:C) model relevant to schizophrenia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
  2020	Effect of cannabidiol on muscarinic neurotransmission in the pre-frontal cortex and hippocampus of the poly I:C rat model of schizophrenia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
  2020	Perinatal exposure to fluoxetine increases anxiety- and depressive-like behaviours and alters glutamatergic markers in the prefrontal cortex and hippocampus of male adolescent rats: A comparison between Sprague-Dawley rats and the Wistar-Kyoto rat model of depression Published In Journal of Psychopharmacology
  2020	The Postprandial Effect of Anthocyanins on Cardiovascular Disease Risk Factors: a Systematic Literature Review of High-Fat Meal Challenge Studies Published In Current Nutrition Reports
  2020	The Wistar-Kyoto rat model of endogenous depression: A tool for exploring treatment resistance with an urgent need to focus on sex differences Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
  2019	Alterations to the microbiota–colon–brain axis in high-fat-diet-induced obese mice compared to diet-resistant mice Published In Journal of Nutritional Biochemistry
  2019	Cannabidiol improves behavioural and neurochemical deficits in adult female offspring of the maternal immune activation (poly I:C) model of neurodevelopmental disorders Published In Brain, Behavior, and Immunity
  2019	Effect of cannabidiol on endocannabinoid, glutamatergic and GABAergic signalling markers in male offspring of a maternal immune activation (poly I:C) model relevant to schizophrenia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
  2019	Effect of cannabidiol on muscarinic neurotransmission in the pre-frontal cortex and hippocampus of the poly I:C rat model of schizophrenia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
  2019	Perinatal exposure to fluoxetine increases anxiety- and depressive-like behaviours and alters glutamatergic markers in the prefrontal cortex and hippocampus of male adolescent rats: A comparison between Sprague-Dawley rats and the Wistar-Kyoto rat model of depression Published In Journal of Psychopharmacology
  2018	Could an allied health care approach reduce the unacceptable incidence of suicide after psychiatric hospital discharge? Published In Bipolar Disorders: an international journal of psychiatry and neurosciences
  2018	Decreased 5‐HT2cR and GHSR1a interaction in antipsychotic drug‐induced obesity Published In Obesity Reviews
  2018	Dietary Galacto-Oligosaccharides and Resistant Starch Protect Against Altered CB1 and 5-HT1A and 2A Receptor Densities in Rat Brain: Implications for Preventing Cognitive and Appetite Dysfunction During a High-Fat Diet Published In Molecular Nutrition and Food Research
  2018	Disrupted sphingolipid metabolism following acute clozapine and olanzapine administration Published In British Journal of Biomedical Science
  2018	Liraglutide prevents metabolic side-effects and improves recognition and working memory during antipsychotic treatment in rats Published In Journal of Psychopharmacology
  2017	A systematic review of the effect of cannabidiol on cognitive function: Relevance to schizophrenia Published In Neuroscience and Biobehavioral Reviews
  2017	Cannabidiol rescues glutamatergic, memory and social interaction deficits following prenatal infection: a follow-up in female offspring Published In European Neuropsychopharmacology
  2017	Improved social interaction, recognition and working memory with cannabidiol treatment in a prenatal infection (poly I:C) rat model Published In Neuropsychopharmacology
  2017	P.3.a.009 Cannabidiol rescues glutamatergic, memory and social interaction deficits following prenatal infection: a follow-up in female offspring Published In European Neuropsychopharmacology
  2017	The effects of maternal antidepressant use on offspring behaviour and brain development: Implications for risk of neurodevelopmental disorders Published In Neuroscience and Biobehavioral Reviews
  2016	A method of providing engaging formative feedback to large cohort first-year physiology and anatomy students Published In Advances in Physiology Education
  2016	Effect of a glucagon-like peptide 1 (GLP-1) receptor agonist, liraglutide, on cognition and body weight during antipsychotic treatment Published In International Journal of Neuropsychopharmacology
  2016	Effect of cannabidiol on cognition in a maternal immune activation (poly IC) model of schizophrenia Published In International Journal of Neuropsychopharmacology
  2013	Second generation antipsychotic-induced type 2 diabetes: a role for the muscarinic M3 receptor Published In CNS Drugs
  2012	Alterations to melanocortinergic, GABAergic and cannabinoid neurotransmission associated with olanzapine-induced weight gain Published In PLoS One
  2012	Effects of olanzapine on muscarinic M3 receptor binding density in the brain relates to weight gain, plasma insulin and metabolic hormone levels Published In European Neuropsychopharmacology
  2011	Olanzapine treatment and metabolic dysfunction: a dose response study in female Sprague Dawley rats Published In Behavioural Brain Research
  2010	Olanzapine decreases POMC MRNA expression and M3 receptors binding density in the hypothalamus and brainstem: pathway for weight gain side-effect? Published In Australian and New Zealand Journal of Psychiatry
  2010	Olanzapine decreases cannabinoid CB1 receptors in the hypothalamus and brainstem, possibly through muscarinic M3 receptor antagonism Published In International Journal of Neuropsychopharmacology
  2010	Sensitivity of the female rat to olanzapine-induced weight gain - far from the clinic? Published In Schizophrenia Research
  2010	The role of histaminergic H1 and H3 receptors in food intake:-A mechanism fo atypical antipsychotic-induced weight gain? Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
  2008	The effects of antipsychotics on the density of cannabinoid receptors in the dorsal vagal complex of rats: Implications for olanzapine-induced weight gain Published In International Journal of Neuropsychopharmacology
  2007	Dose-dependent effects of atypical antipsychotic drug olanzapine on weight gain and cholecystokinin levels in rats Published In Neuroscience Bulletin
  2007	Olanzapine treatment decreases the density of muscarinic M2 receptors in the dorsal vagal complex of rats Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry

• Chapter

  Year	Title
  2020	The United Chemicals of Cannabis: Beneficial Effects of Cannabis Phytochemicals on the Brain and Cognition Published In Recent Advances in Cannabinoid Research Publisher London, United Kingdom
  2019	The United Chemicals of Cannabis: Beneficial Effects of Cannabis Phytochemicals on the Brain and Cognition Published In Recent Advances in Cannabinoid Research Publisher London, United Kingdom

• Conference Paper

  Year	Title
  2020	Liraglutide prevents dysregulation of markers of cognitive function during antipsychotic drug treatment in rats. Biological Psychiatry Australia 19-21 October 2020, virtual conference.
  2018	Understanding the efficacy of GLP-1 receptor agonist, liraglutide, to prevent olanzapine-induced weight gain in rats: examining NPY in the hypothalamus
  2017	Cannabidiol improves behavioural and glutamatergic deficits in a prenatal infection model of schizophrenia Published In 27th Annual Symposium of the International Cannabinoid Research Society
  2017	Decreased 5-HT2cR and GHSR1a dimerization by olanzapine contributes to increased hypothalamic NPY and obesity side-effects Published In 7th Annual Scientific Meeting Abstract Book
  2017	The effects of cannabis molecule, cannabidiol (CBD), on dopaminergic signalling: A systematic review of the literature Published In 7th Annual Scientific Meeting Abstract Book
  2016	A systematic review of the effect of cannabidiol on cognitive function: relevance to Schizophrenia Published In 6th Annual Scientific Meeting Abstract Book
  2016	Effect of a glucagon-like peptide 1 (GLP-1) receptor agonist, liraglutide, on cognition and body weight during antipsychotic treatment Published In INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
  2016	Effect of a glucagon-like peptide 1 (GLP-1) receptor agonist, liraglutide, on metabolic parameters during antipsychotic treatment.
  2016	Effect of cannabidiol on cognition in a maternal immune activation (poly IC) model of schizophrenia Published In INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
  2016	Novel therapeutic approaches to treating cognitive deficits of schizophrenia Published In 6th Annual Scientific Meeting Abstract Book
  2013	Binding affinity of aripiprazole to the dopamine D2 receptor in different regions of the rat brain Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants
  2012	Differential effects of aripiprazole and haloperidol on dopamine markers in the arcuate nucleus and prolactin levels in male rats Published In The International Journal of Neuropsychopharmacology: Abstracts from the 28th CINP World Congress of Neuropsychopharmacology
  2011	Neuroendocrinological regulation of insulin dysfunction induced by olanzapine Published In 31st Annual Meeting of the Australian Neuroscience Society
  2010	Olanzapine decreases [3H]SR141716A binding to cannabinoid CB1 receptors in the rat hippocampus and auditory cortex: a dosage-dependent response Published In Australian Neuroscience Society Annual Meeting, Sydney 2010
  2010	Olanzapine-induced metabolic dysfunction: a role for central muscarinic M3 receptors Published In Australian Neuroscience Society Annual Meeting, Sydney 2010
  2010	The dosage response to the side-effect of metabolic dysfunction in female rats following olanzapine treatment Published In Australian Neuroscience Society Annual Meeting, Sydney 2010
  2007	Effects of antipsychotic drugs on weight gain and CB1 receptors in the dorsal vagal complex of rats Published In 7th IBRO World Congress of Neuroscience

Investigator On

Year	Title
2021 - 2024	Food for thought: Preventing decline and improving cognition through diet and dietary advice in older people at risk Awarded by: Dementia Centre for Research Collaboration Funding Scheme: World Class Research Project Grant
2020 - 2021	The United Colours of Cannabis: A novel approach to treating the cognitive symptoms of schizophrenia Awarded by: Rebecca L Cooper Medical Research Foundation Funding Scheme: Medical Research Project Grant
2018	Forced exercise/walking wheel system for rats Model 80805A Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2015 - 2016	Improving pharmacological treatment of Schizophrenia: Focus on cognition and metabolic side-effects Awarded by: Schizophrenia Fellowship of NSW Funding Scheme: Peter Meyer Fund
2014	SR-LAB ABS System Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
	Investigating the mechanisms underlying the beneficial effects of liraglutide on cognition during antipsychotic treatment Awarded by: Neuroscience Research Australia (NeuRA) Funding Scheme: Research in Schizophrenia Endeavour (RISE) Award 2019

Impact Story

Potential Supervision Topics

• Dr Green's research aims to discover new pharmacological treatments for illnesses of the brain where existing medications are lacking in efficacy. Examples of topics for potential Higher Degree Research students include (not limited to):
  
  • Examining effects of phytochemicals derived from natural sources (eg cannabis / hemp, fruits / berries) on the brain and behaviour (and the underlying mechanisms of benefits/harms)
  • Investigating the role of gut microbiota on brain function / illness (and underlying mechanisms)
  • Understanding the pathogenesis of cognitive dysfunction during brain illness
  Preclinical (cell and rodent models) and clinical research programs available.

Advisees

• Graduate Advising Relationship

  Degree	Research Title	Advisee
  Doctor of Philosophy	Two Birds, One Hormone: Addressing Cognitive Impairment and the Metabolic Side-Effects of Antipsychotic Drugs with Liragutide, a GLP-1 Receptor Agonist
  Doctor of Philosophy (Integrated)	The Molecular Mechanism of Microbiota-Gut-Brain Axis Influenced by Dietary Fibre Types	Wang, Zhizhen
  Doctor of Philosophy	Efficacy Investigation of Terpenes and Cannabidiol in a Rodent Model of Depression	Clunas, Helen
  Master of Research -SMAH	Investigating Cognition in Chronic Opioid Use, Potential Role of the Gut Microbiota	Nair, Mayank
  Doctor of Philosophy	Harnessing the power of plants: Using phytochemicals on cognition, anxiety and depression as well as underlying mechanisms	May, Naomi
  Doctor of Philosophy	Investigation into the Chemistry of Cannabis Vaporisation	Gschwend, Grace
  Doctor of Philosophy	Vitamin D supplementation in Type 2 diabetes	Lorzadeh, Elnaz

Keywords

• Cannabis; cognition; neuropharmacology; mental illness; new treatment; horticulture; anthocyanin; flavonoid; psychiatry; schizophrenia; bipolar disorder; depression; anxiety; learning; memory; animal model; cannabidiol; terpene; entourage effect; ketamine; antipsychotic; GLP-1; neuroscience; microbiota; gut bacteria

Orcid Id

• http://orcid.org/0000-0002-4521-8463 (confirmed)

Scopus Id

• 16243089800

Top Publications

Year	Title
2019	The United Chemicals of Cannabis: Beneficial Effects of Cannabis Phytochemicals on the Brain and Cognition
2019	Alterations to the microbiota–colon–brain axis in high-fat-diet-induced obese mice compared to diet-resistant mice Published in   Journal of Nutritional Biochemistry
2018	Liraglutide prevents metabolic side-effects and improves recognition and working memory during antipsychotic treatment in rats Published in   Journal of Psychopharmacology
2017	A systematic review of the effect of cannabidiol on cognitive function: Relevance to schizophrenia Published in   Neuroscience and Biobehavioral Reviews
2017	Improved social interaction, recognition and working memory with cannabidiol treatment in a prenatal infection (poly I:C) rat model Published in   Neuropsychopharmacology
2017	The effects of maternal antidepressant use on offspring behaviour and brain development: Implications for risk of neurodevelopmental disorders Published in   Neuroscience and Biobehavioral Reviews

Research Areas

• 110319 - PSYCHIATRY (INCL. PSYCHOTHERAPY)
• 1109 - NEUROSCIENCES
• 170101 - BIOLOGICAL PSYCHOLOGY (NEUROPSYCHOLOGY, PSYCHOPHARMACOLOGY, PHYSIOLOGICAL PSYCHOLOGY)

Research Overview

• Cannabis cognition mental illness horticulture anthocyanin flavonoid psychiatry schizophrenia bipolar disorder depression anxiety learning memory animal model cannabidiol terpene entourage effect ketamine antipsychotic GLP-1 neuroscience microbiota gut bacteria

Head Of

• Neuropharmacology and Molecular Psychiatry Co-Head 2016 -

Member Of

• Australian Centre for Cannabinoid Clinical and Research Excellence Capacity Building Committee Deputy Chair 2018 -
• Molecular Horizons Executive Committee 2018 -
• Academic Senate - UOW SMAH Faculty Representative 2017 -
• Australian Centre for Cannabinoid Clinical and Research Excellence (ACRE), A National Health and Medical Research Council Centre of Research Excellence Scientific Affiliate (Associate Investigator): Preclinical and Clinical Studies of Medicinal Cannabinoids panel 2017 -
• Collegium Internationale Neuro-Psychopharmacologicum (CINP) Member 2017 -
• Illawarra Shoalhaven Local Health District Honorary Research Associate 2017 -
• Medicinal Cannabis Council Australia Member 2017 -
• Biological Psychiatry Australia Member, Senior Mentor to ECR Network Committee 2013 -
• Neuroendocrinology, (Karger, Switzerland) Member of Editorial Board 2013 -
• Illawarra Health and Medical Research Institute Scientific Affiliate 2008 -

Clinical Activities

• Investigating the link between gut microbiota and cognitive function in psychiatric illness and substance abuse Lead Researcher 2017 -

Selected Publications

• Journal Article

  Year	Title
  2022	Cannabidiol induces autophagy and improves neuronal health associated with SIRT1 mediated longevity Published In GeroScience
  2021	A Review of the Potential Use of Pinene and Linalool as Terpene-Based Medicines for Brain Health: Discovering Novel Therapeutics in the Flavours and Fragrances of Cannabis Published In Frontiers in Psychiatry
  2021	Anthocyanins attenuate vascular and inflammatory responses to a high fat high energy meal challenge in overweight older adults: A cross-over, randomized, double-blind clinical trial Published In Clinical Nutrition
  2021	Association between flavonoid intake and risk of hypertension in two cohorts of Australian women: a longitudinal study Published In European Journal of Nutrition
  2021	Cannabidiol regulates CB1-pSTAT3 signaling for neurite outgrowth, prolongs lifespan, and improves health span in Caenorhabditis elegans of Aß pathology models Published In FASEB Journal
  2021	Effect of liraglutide on neural and peripheral markers of metabolic function during antipsychotic treatment in rats Published In Journal of Psychopharmacology
  2021	Food anthocyanins decrease concentrations of TNF-a in older adults with mild cognitive impairment: A randomized, controlled, double blind clinical trial Published In Nutrition, Metabolism and Cardiovascular Diseases
  2021	The effects of perinatal fluoxetine exposure on emotionality behaviours and cortical and hippocampal glutamatergic receptors in female Sprague-Dawley and Wistar-Kyoto rats Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
  2020	Alterations to the microbiota–colon–brain axis in high-fat-diet-induced obese mice compared to diet-resistant mice Published In Journal of Nutritional Biochemistry
  2020	Cannabidiol improves behavioural and neurochemical deficits in adult female offspring of the maternal immune activation (poly I:C) model of neurodevelopmental disorders Published In Brain, Behavior, and Immunity
  2020	Effect of cannabidiol on endocannabinoid, glutamatergic and GABAergic signalling markers in male offspring of a maternal immune activation (poly I:C) model relevant to schizophrenia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
  2020	Effect of cannabidiol on muscarinic neurotransmission in the pre-frontal cortex and hippocampus of the poly I:C rat model of schizophrenia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
  2020	Perinatal exposure to fluoxetine increases anxiety- and depressive-like behaviours and alters glutamatergic markers in the prefrontal cortex and hippocampus of male adolescent rats: A comparison between Sprague-Dawley rats and the Wistar-Kyoto rat model of depression Published In Journal of Psychopharmacology
  2020	The Postprandial Effect of Anthocyanins on Cardiovascular Disease Risk Factors: a Systematic Literature Review of High-Fat Meal Challenge Studies Published In Current Nutrition Reports
  2020	The Wistar-Kyoto rat model of endogenous depression: A tool for exploring treatment resistance with an urgent need to focus on sex differences Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
  2019	Alterations to the microbiota–colon–brain axis in high-fat-diet-induced obese mice compared to diet-resistant mice Published In Journal of Nutritional Biochemistry
  2019	Cannabidiol improves behavioural and neurochemical deficits in adult female offspring of the maternal immune activation (poly I:C) model of neurodevelopmental disorders Published In Brain, Behavior, and Immunity
  2019	Effect of cannabidiol on endocannabinoid, glutamatergic and GABAergic signalling markers in male offspring of a maternal immune activation (poly I:C) model relevant to schizophrenia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
  2019	Effect of cannabidiol on muscarinic neurotransmission in the pre-frontal cortex and hippocampus of the poly I:C rat model of schizophrenia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
  2019	Perinatal exposure to fluoxetine increases anxiety- and depressive-like behaviours and alters glutamatergic markers in the prefrontal cortex and hippocampus of male adolescent rats: A comparison between Sprague-Dawley rats and the Wistar-Kyoto rat model of depression Published In Journal of Psychopharmacology
  2018	Could an allied health care approach reduce the unacceptable incidence of suicide after psychiatric hospital discharge? Published In Bipolar Disorders: an international journal of psychiatry and neurosciences
  2018	Decreased 5‐HT2cR and GHSR1a interaction in antipsychotic drug‐induced obesity Published In Obesity Reviews
  2018	Dietary Galacto-Oligosaccharides and Resistant Starch Protect Against Altered CB1 and 5-HT1A and 2A Receptor Densities in Rat Brain: Implications for Preventing Cognitive and Appetite Dysfunction During a High-Fat Diet Published In Molecular Nutrition and Food Research
  2018	Disrupted sphingolipid metabolism following acute clozapine and olanzapine administration Published In British Journal of Biomedical Science
  2018	Liraglutide prevents metabolic side-effects and improves recognition and working memory during antipsychotic treatment in rats Published In Journal of Psychopharmacology
  2017	A systematic review of the effect of cannabidiol on cognitive function: Relevance to schizophrenia Published In Neuroscience and Biobehavioral Reviews
  2017	Cannabidiol rescues glutamatergic, memory and social interaction deficits following prenatal infection: a follow-up in female offspring Published In European Neuropsychopharmacology
  2017	Improved social interaction, recognition and working memory with cannabidiol treatment in a prenatal infection (poly I:C) rat model Published In Neuropsychopharmacology
  2017	P.3.a.009 Cannabidiol rescues glutamatergic, memory and social interaction deficits following prenatal infection: a follow-up in female offspring Published In European Neuropsychopharmacology
  2017	The effects of maternal antidepressant use on offspring behaviour and brain development: Implications for risk of neurodevelopmental disorders Published In Neuroscience and Biobehavioral Reviews
  2016	A method of providing engaging formative feedback to large cohort first-year physiology and anatomy students Published In Advances in Physiology Education
  2016	Effect of a glucagon-like peptide 1 (GLP-1) receptor agonist, liraglutide, on cognition and body weight during antipsychotic treatment Published In International Journal of Neuropsychopharmacology
  2016	Effect of cannabidiol on cognition in a maternal immune activation (poly IC) model of schizophrenia Published In International Journal of Neuropsychopharmacology
  2013	Second generation antipsychotic-induced type 2 diabetes: a role for the muscarinic M3 receptor Published In CNS Drugs
  2012	Alterations to melanocortinergic, GABAergic and cannabinoid neurotransmission associated with olanzapine-induced weight gain Published In PLoS One
  2012	Effects of olanzapine on muscarinic M3 receptor binding density in the brain relates to weight gain, plasma insulin and metabolic hormone levels Published In European Neuropsychopharmacology
  2011	Olanzapine treatment and metabolic dysfunction: a dose response study in female Sprague Dawley rats Published In Behavioural Brain Research
  2010	Olanzapine decreases POMC MRNA expression and M3 receptors binding density in the hypothalamus and brainstem: pathway for weight gain side-effect? Published In Australian and New Zealand Journal of Psychiatry
  2010	Olanzapine decreases cannabinoid CB1 receptors in the hypothalamus and brainstem, possibly through muscarinic M3 receptor antagonism Published In International Journal of Neuropsychopharmacology
  2010	Sensitivity of the female rat to olanzapine-induced weight gain - far from the clinic? Published In Schizophrenia Research
  2010	The role of histaminergic H1 and H3 receptors in food intake:-A mechanism fo atypical antipsychotic-induced weight gain? Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
  2008	The effects of antipsychotics on the density of cannabinoid receptors in the dorsal vagal complex of rats: Implications for olanzapine-induced weight gain Published In International Journal of Neuropsychopharmacology
  2007	Dose-dependent effects of atypical antipsychotic drug olanzapine on weight gain and cholecystokinin levels in rats Published In Neuroscience Bulletin
  2007	Olanzapine treatment decreases the density of muscarinic M2 receptors in the dorsal vagal complex of rats Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry

• Chapter

  Year	Title
  2020	The United Chemicals of Cannabis: Beneficial Effects of Cannabis Phytochemicals on the Brain and Cognition Published In Recent Advances in Cannabinoid Research Publisher London, United Kingdom
  2019	The United Chemicals of Cannabis: Beneficial Effects of Cannabis Phytochemicals on the Brain and Cognition Published In Recent Advances in Cannabinoid Research Publisher London, United Kingdom

• Conference Paper

  Year	Title
  2020	Liraglutide prevents dysregulation of markers of cognitive function during antipsychotic drug treatment in rats. Biological Psychiatry Australia 19-21 October 2020, virtual conference.
  2018	Understanding the efficacy of GLP-1 receptor agonist, liraglutide, to prevent olanzapine-induced weight gain in rats: examining NPY in the hypothalamus
  2017	Cannabidiol improves behavioural and glutamatergic deficits in a prenatal infection model of schizophrenia Published In 27th Annual Symposium of the International Cannabinoid Research Society
  2017	Decreased 5-HT2cR and GHSR1a dimerization by olanzapine contributes to increased hypothalamic NPY and obesity side-effects Published In 7th Annual Scientific Meeting Abstract Book
  2017	The effects of cannabis molecule, cannabidiol (CBD), on dopaminergic signalling: A systematic review of the literature Published In 7th Annual Scientific Meeting Abstract Book
  2016	A systematic review of the effect of cannabidiol on cognitive function: relevance to Schizophrenia Published In 6th Annual Scientific Meeting Abstract Book
  2016	Effect of a glucagon-like peptide 1 (GLP-1) receptor agonist, liraglutide, on cognition and body weight during antipsychotic treatment Published In INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
  2016	Effect of a glucagon-like peptide 1 (GLP-1) receptor agonist, liraglutide, on metabolic parameters during antipsychotic treatment.
  2016	Effect of cannabidiol on cognition in a maternal immune activation (poly IC) model of schizophrenia Published In INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
  2016	Novel therapeutic approaches to treating cognitive deficits of schizophrenia Published In 6th Annual Scientific Meeting Abstract Book
  2013	Binding affinity of aripiprazole to the dopamine D2 receptor in different regions of the rat brain Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants
  2012	Differential effects of aripiprazole and haloperidol on dopamine markers in the arcuate nucleus and prolactin levels in male rats Published In The International Journal of Neuropsychopharmacology: Abstracts from the 28th CINP World Congress of Neuropsychopharmacology
  2011	Neuroendocrinological regulation of insulin dysfunction induced by olanzapine Published In 31st Annual Meeting of the Australian Neuroscience Society
  2010	Olanzapine decreases [3H]SR141716A binding to cannabinoid CB1 receptors in the rat hippocampus and auditory cortex: a dosage-dependent response Published In Australian Neuroscience Society Annual Meeting, Sydney 2010
  2010	Olanzapine-induced metabolic dysfunction: a role for central muscarinic M3 receptors Published In Australian Neuroscience Society Annual Meeting, Sydney 2010
  2010	The dosage response to the side-effect of metabolic dysfunction in female rats following olanzapine treatment Published In Australian Neuroscience Society Annual Meeting, Sydney 2010
  2007	Effects of antipsychotic drugs on weight gain and CB1 receptors in the dorsal vagal complex of rats Published In 7th IBRO World Congress of Neuroscience

Investigator On

Year	Title
2021 - 2024	Food for thought: Preventing decline and improving cognition through diet and dietary advice in older people at risk Awarded by: Dementia Centre for Research Collaboration Funding Scheme: World Class Research Project Grant
2020 - 2021	The United Colours of Cannabis: A novel approach to treating the cognitive symptoms of schizophrenia Awarded by: Rebecca L Cooper Medical Research Foundation Funding Scheme: Medical Research Project Grant
2018	Forced exercise/walking wheel system for rats Model 80805A Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2015 - 2016	Improving pharmacological treatment of Schizophrenia: Focus on cognition and metabolic side-effects Awarded by: Schizophrenia Fellowship of NSW Funding Scheme: Peter Meyer Fund
2014	SR-LAB ABS System Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
	Investigating the mechanisms underlying the beneficial effects of liraglutide on cognition during antipsychotic treatment Awarded by: Neuroscience Research Australia (NeuRA) Funding Scheme: Research in Schizophrenia Endeavour (RISE) Award 2019

Impact Story

Potential Supervision Topics

• Dr Green's research aims to discover new pharmacological treatments for illnesses of the brain where existing medications are lacking in efficacy. Examples of topics for potential Higher Degree Research students include (not limited to):
  
  • Examining effects of phytochemicals derived from natural sources (eg cannabis / hemp, fruits / berries) on the brain and behaviour (and the underlying mechanisms of benefits/harms)
  • Investigating the role of gut microbiota on brain function / illness (and underlying mechanisms)
  • Understanding the pathogenesis of cognitive dysfunction during brain illness
  Preclinical (cell and rodent models) and clinical research programs available.

Advisees

• Graduate Advising Relationship

  Degree	Research Title	Advisee
  Doctor of Philosophy	Two Birds, One Hormone: Addressing Cognitive Impairment and the Metabolic Side-Effects of Antipsychotic Drugs with Liragutide, a GLP-1 Receptor Agonist
  Doctor of Philosophy (Integrated)	The Molecular Mechanism of Microbiota-Gut-Brain Axis Influenced by Dietary Fibre Types	Wang, Zhizhen
  Doctor of Philosophy	Efficacy Investigation of Terpenes and Cannabidiol in a Rodent Model of Depression	Clunas, Helen
  Master of Research -SMAH	Investigating Cognition in Chronic Opioid Use, Potential Role of the Gut Microbiota	Nair, Mayank
  Doctor of Philosophy	Harnessing the power of plants: Using phytochemicals on cognition, anxiety and depression as well as underlying mechanisms	May, Naomi
  Doctor of Philosophy	Investigation into the Chemistry of Cannabis Vaporisation	Gschwend, Grace
  Doctor of Philosophy	Vitamin D supplementation in Type 2 diabetes	Lorzadeh, Elnaz

Keywords

• Cannabis; cognition; neuropharmacology; mental illness; new treatment; horticulture; anthocyanin; flavonoid; psychiatry; schizophrenia; bipolar disorder; depression; anxiety; learning; memory; animal model; cannabidiol; terpene; entourage effect; ketamine; antipsychotic; GLP-1; neuroscience; microbiota; gut bacteria

Orcid Id

• http://orcid.org/0000-0002-4521-8463 (confirmed)

Scopus Id

• 16243089800