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Journal of Medicinal Chemistry
Journal
Identity
International Standard Serial Number (issn)
Other
Publication Venue For
-
Rapid Elaboration of Fragments into Leads by X-ray Crystallographic Screening of Parallel Chemical Libraries (REFiLX)
2020
-
Rational Design and Synthesis of Methyl-β-d-galactomalonyl Phenyl Esters as Potent Galectin-8N Antagonists
2020
-
6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer
2018
-
Molecular Determinants Conferring the Stoichiometric-Dependent Activity of alpha-Conotoxins at the Human alpha 9 alpha 10 Nicotinic Acetylcholine Receptor Subtype
2018
-
Reviewing Hit Discovery Literature for Difficult Targets: Glutathione Transferase Omega-1 as an Example
2018
-
Targeting of N-Type Calcium Channels via GABAB-Receptor Activation by α-Conotoxin Vc1.1 Variants Displaying Improved Analgesic Activity
2018
-
5′-substituted amiloride derivatives as allosteric modulators binding in the sodium ion pocket of the adenosine A2A receptor
2016
-
Bacterial sliding clamp inhibitors that mimic the sequential binding mechanism of endogenous linear motifs
2015
-
Peptide inhibitors of the Escherichia coli DsbA oxidative machinery essential for bacterial virulence
2015
-
Chikungunya virus: emerging targets and new opportunities for medicinal chemistry
2014
-
Dicarba analogues of α-conotoxin RgIA. Structure, stability, and activity at potential pain targets
2014
-
Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach
2014
-
Determination of the α-conotoxin Vc1.1 binding site on the α9α10 nicotinic acetylcholine receptor
2013
-
Structural and thermodynamic dissection of linear motif recognition by the E. coli sliding clamp
2013
-
Binding inhibitors of the bacterial sliding clamp by design
2011
-
Effects of cyclization on stability, structure, and activity of α-conotoxin RgIA at the α9α10 nicotinic acetylcholine receptor and GABAB receptor
2011
-
Structural and functional basis of resistance to neuraminidase inhibitors of influenza B viruses.
2010
-
Synthesis, biodistribution, and microsingle photon emission computed tomography (SPECT) imaging study of technetium-99m labeled PEGylated dendrimer poly(amidoamine) (PAMAM)-folic acid conjugates
2010
-
The Medicinal Chemistry of Dengue Fever
2009
-
Molecular engineering of conotoxins: The importance of loop size to α-conotoxin structure and function
2008
-
An investigation into the Cytotoxicity and mode of action of some Novel N-Alkyl-Substituted Isatins
2007
-
Enzyme adaptation to inhibitor binding: A cryptic binding site in phenylethanolamine N-methyltransferase
2007
-
Structure-activity relationships of alpha-ketooxazole inhibitors of fatty acid amide hydrolase
2007
-
Comparison of the binding of 3-fluoromethyl-7-sulfonyl-1,2,3,4- tetrahydroisoquinolines with their isosteric sulfonamides to the active site of phenylethanolamine N-methyltransferase
2006
-
Structural, mutagenic, and kinetic analysis of the binding of substrates and inhibitors of human phenylethanolamine N-methyltransferase
2005
-
Chemical and functional identification and characterization of novel sulfated α-conotoxins from the cone snail Conus anemone
2004
-
Countering Cooperative Effects in Protease Inhibitors Using Constrained β-Strand-Mimicking Templates in Focused Combinatorial Libraries
2004
-
Molecular Recognition of Sub-micromolar Inhibitors by the Epinephrine-Synthesizing Enzyme Phenylethanolamine N-Methyltransferase
2004
-
Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of α-conotoxin MII
2003
-
Synthesis, stability, antiviral activity, and protease-bound structures of substrate-mimicking constrained macrocyclic inhibitors of HIV-1 protease
2000
-
Functional Group Contributions to Drug-Receptor Interactions
1984
Identity
International Standard Serial Number (issn)
Other
Publication Venue For
-
Rapid Elaboration of Fragments into Leads by X-ray Crystallographic Screening of Parallel Chemical Libraries (REFiLX)
2020
-
Rational Design and Synthesis of Methyl-β-d-galactomalonyl Phenyl Esters as Potent Galectin-8N Antagonists
2020
-
6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer
2018
-
Molecular Determinants Conferring the Stoichiometric-Dependent Activity of alpha-Conotoxins at the Human alpha 9 alpha 10 Nicotinic Acetylcholine Receptor Subtype
2018
-
Reviewing Hit Discovery Literature for Difficult Targets: Glutathione Transferase Omega-1 as an Example
2018
-
Targeting of N-Type Calcium Channels via GABAB-Receptor Activation by α-Conotoxin Vc1.1 Variants Displaying Improved Analgesic Activity
2018
-
5′-substituted amiloride derivatives as allosteric modulators binding in the sodium ion pocket of the adenosine A2A receptor
2016
-
Bacterial sliding clamp inhibitors that mimic the sequential binding mechanism of endogenous linear motifs
2015
-
Peptide inhibitors of the Escherichia coli DsbA oxidative machinery essential for bacterial virulence
2015
-
Chikungunya virus: emerging targets and new opportunities for medicinal chemistry
2014
-
Dicarba analogues of α-conotoxin RgIA. Structure, stability, and activity at potential pain targets
2014
-
Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach
2014
-
Determination of the α-conotoxin Vc1.1 binding site on the α9α10 nicotinic acetylcholine receptor
2013
-
Structural and thermodynamic dissection of linear motif recognition by the E. coli sliding clamp
2013
-
Binding inhibitors of the bacterial sliding clamp by design
2011
-
Effects of cyclization on stability, structure, and activity of α-conotoxin RgIA at the α9α10 nicotinic acetylcholine receptor and GABAB receptor
2011
-
Structural and functional basis of resistance to neuraminidase inhibitors of influenza B viruses.
2010
-
Synthesis, biodistribution, and microsingle photon emission computed tomography (SPECT) imaging study of technetium-99m labeled PEGylated dendrimer poly(amidoamine) (PAMAM)-folic acid conjugates
2010
-
The Medicinal Chemistry of Dengue Fever
2009
-
Molecular engineering of conotoxins: The importance of loop size to α-conotoxin structure and function
2008
-
An investigation into the Cytotoxicity and mode of action of some Novel N-Alkyl-Substituted Isatins
2007
-
Enzyme adaptation to inhibitor binding: A cryptic binding site in phenylethanolamine N-methyltransferase
2007
-
Structure-activity relationships of alpha-ketooxazole inhibitors of fatty acid amide hydrolase
2007
-
Comparison of the binding of 3-fluoromethyl-7-sulfonyl-1,2,3,4- tetrahydroisoquinolines with their isosteric sulfonamides to the active site of phenylethanolamine N-methyltransferase
2006
-
Structural, mutagenic, and kinetic analysis of the binding of substrates and inhibitors of human phenylethanolamine N-methyltransferase
2005
-
Chemical and functional identification and characterization of novel sulfated α-conotoxins from the cone snail Conus anemone
2004
-
Countering Cooperative Effects in Protease Inhibitors Using Constrained β-Strand-Mimicking Templates in Focused Combinatorial Libraries
2004
-
Molecular Recognition of Sub-micromolar Inhibitors by the Epinephrine-Synthesizing Enzyme Phenylethanolamine N-Methyltransferase
2004
-
Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of α-conotoxin MII
2003
-
Synthesis, stability, antiviral activity, and protease-bound structures of substrate-mimicking constrained macrocyclic inhibitors of HIV-1 protease
2000
-
Functional Group Contributions to Drug-Receptor Interactions
1984