Journal of Medicinal Chemistry

Journal

International Standard Serial Number (issn)

1520-4804

Publication Venue For

Rapid Elaboration of Fragments into Leads by X-ray Crystallographic Screening of Parallel Chemical Libraries (REFiLX) 2020
Rational Design and Synthesis of Methyl-β-d-galactomalonyl Phenyl Esters as Potent Galectin-8N Antagonists 2020
6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer 2018
Molecular Determinants Conferring the Stoichiometric-Dependent Activity of alpha-Conotoxins at the Human alpha 9 alpha 10 Nicotinic Acetylcholine Receptor Subtype 2018
Reviewing Hit Discovery Literature for Difficult Targets: Glutathione Transferase Omega-1 as an Example 2018
Targeting of N-Type Calcium Channels via GABAB-Receptor Activation by α-Conotoxin Vc1.1 Variants Displaying Improved Analgesic Activity 2018
5′-substituted amiloride derivatives as allosteric modulators binding in the sodium ion pocket of the adenosine A_2A receptor 2016
Bacterial sliding clamp inhibitors that mimic the sequential binding mechanism of endogenous linear motifs 2015
Peptide inhibitors of the Escherichia coli DsbA oxidative machinery essential for bacterial virulence 2015
Chikungunya virus: emerging targets and new opportunities for medicinal chemistry 2014
Dicarba analogues of α-conotoxin RgIA. Structure, stability, and activity at potential pain targets 2014
Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach 2014
Determination of the α-conotoxin Vc1.1 binding site on the α9α10 nicotinic acetylcholine receptor 2013
Structural and thermodynamic dissection of linear motif recognition by the E. coli sliding clamp 2013
Binding inhibitors of the bacterial sliding clamp by design 2011
Effects of cyclization on stability, structure, and activity of α-conotoxin RgIA at the α9α10 nicotinic acetylcholine receptor and GABAB receptor 2011
Structural and functional basis of resistance to neuraminidase inhibitors of influenza B viruses. 2010
Synthesis, biodistribution, and microsingle photon emission computed tomography (SPECT) imaging study of technetium-99m labeled PEGylated dendrimer poly(amidoamine) (PAMAM)-folic acid conjugates 2010
The Medicinal Chemistry of Dengue Fever 2009
Molecular engineering of conotoxins: The importance of loop size to α-conotoxin structure and function 2008
An investigation into the Cytotoxicity and mode of action of some Novel N-Alkyl-Substituted Isatins 2007
Enzyme adaptation to inhibitor binding: A cryptic binding site in phenylethanolamine N-methyltransferase 2007
Structure-activity relationships of alpha-ketooxazole inhibitors of fatty acid amide hydrolase 2007
Comparison of the binding of 3-fluoromethyl-7-sulfonyl-1,2,3,4- tetrahydroisoquinolines with their isosteric sulfonamides to the active site of phenylethanolamine N-methyltransferase 2006
Structural, mutagenic, and kinetic analysis of the binding of substrates and inhibitors of human phenylethanolamine N-methyltransferase 2005
Chemical and functional identification and characterization of novel sulfated α-conotoxins from the cone snail Conus anemone 2004
Countering Cooperative Effects in Protease Inhibitors Using Constrained β-Strand-Mimicking Templates in Focused Combinatorial Libraries 2004
Molecular Recognition of Sub-micromolar Inhibitors by the Epinephrine-Synthesizing Enzyme Phenylethanolamine N-Methyltransferase 2004
Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of α-conotoxin MII 2003
Synthesis, stability, antiviral activity, and protease-bound structures of substrate-mimicking constrained macrocyclic inhibitors of HIV-1 protease 2000
Functional Group Contributions to Drug-Receptor Interactions 1984

International Standard Serial Number (issn)

1520-4804

Publication Venue For