Lum, Jeremy

Selected Publications

• Journal Article

  Year	Title
  2022	An Optimized Direct Lysis Gene Expression Microplate Assay and Applications for Disease, Differentiation, and Pharmacological Cell-Based Studies Published In Biosensors
  2022	Cells Overexpressing ALS-Associated SOD1 Variants Are Differentially Susceptible to CuATSM-Associated Toxicity Published In ACS Chemical Neuroscience
  2022	Misfolding at the synapse: A role in amyotrophic lateral sclerosis pathogenesis? Published In Frontiers in Molecular Neuroscience
  2022	Ubiquitin homeostasis disruption, a common cause of proteostasis collapse in amyotrophic lateral sclerosis? Published In Neural Regeneration Research
  2022	Vulnerability of the spinal motor neuron presynaptic terminal sub-proteome in ALS Published In Neuroscience Letters
  2021	CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1 G93A mice with a C57BL/6 background Published In Scientific Reports
  2021	Prenatal methadone exposure impairs adolescent cognition and GABAergic neurodevelopment in a novel rat model of maternal methadone treatment Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
  2021	Sex differences in the neurochemistry of frontal cortex: Impact of early life stress Published In Journal of Neurochemistry
  2021	The effects of perinatal fluoxetine exposure on emotionality behaviours and cortical and hippocampal glutamatergic receptors in female Sprague-Dawley and Wistar-Kyoto rats Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
  2020	Amyotrophic Lateral Sclerosis: Proteins, Proteostasis, Prions, and Promises Published In Frontiers in Cellular Neuroscience
  2020	Identification of repurposable cytoprotective drugs in vanishing white matter disease patient-derived cells Published In Translational Medicine Communications
  2020	Supplement of microbiota-accessible carbohydrates prevents neuroinflammation and cognitive decline by improving the gut microbiota-brain axis in diet-induced obese mice Published In Journal of Neuroinflammation
  2020	Ubiquitin Homeostasis Is Disrupted in TDP-43 and FUS Cell Models of ALS Published In iScience
  2019	Cannabidiol improves behavioural and neurochemical deficits in adult female offspring of the maternal immune activation (poly I:C) model of neurodevelopmental disorders Published In Brain, Behavior, and Immunity
  2019	Effect of cannabidiol on endocannabinoid, glutamatergic and GABAergic signalling markers in male offspring of a maternal immune activation (poly I:C) model relevant to schizophrenia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
  2019	Increased translocator protein (TSPO) binding throughout neurodevelopment in the perinatal phencyclidine rodent model of schizophrenia Published In Schizophrenia Research
  2019	Perinatal exposure to fluoxetine increases anxiety- and depressive-like behaviours and alters glutamatergic markers in the prefrontal cortex and hippocampus of male adolescent rats: A comparison between Sprague-Dawley rats and the Wistar-Kyoto rat model of depression Published In Journal of Psychopharmacology
  2018	A postmortem analysis of NMDA ionotropic and group 1 metabotropic glutamate receptors in the nucleus accumbens in schizophrenia Published In Journal of Psychiatry and Neuroscience
  2018	A postmortem analysis of NMDA ionotropic and group 1 metabotropic glutamate receptors in the nucleus accumbens in schizophrenia. Published In Journal of psychiatry & neuroscience : JPN
  2018	Chronic Adolescent CDPPB Treatment Alters Short-Term, but not Long-Term, Glutamatergic Receptor Expression Published In Neurochemical Research
  2018	Effects of short- and long-term aripiprazole treatment on Group I mGluRs in the nucleus accumbens: Comparison with haloperidol Published In Psychiatry Research
  2017	Shifting towards a model of mGluR5 dysregulation in schizophrenia: consequences for future schizophrenia treatment Published In Neuropharmacology
  2016	Molecular evidence of synaptic pathology in CA1 in schizophrenia Published In Biological Psychiatry
  2016	Molecular evidence of synaptic pathology in the CA1 region in schizophrenia Published In NPJ Schizophrenia
  2016	Neurodevelopmental expression profile of dimeric and monomeric group 1 mGluRs: relevance to schizophrenia pathogenesis and treatment Published In Scientific Reports
  2016	Neuroprotective effects of apigenin against inflammation, neuronal excitability and apoptosis in an induced pluripotent stem cell model of Alzheimer’s disease Published In Scientific Reports
  2016	PS130. Maternal fluoxetine treatment influences anxiety- and depressive-like behaviours in adolescent offspring: a rodent model Published In The International Journal of Neuropsychopharmacology
  2016	PS146. Norbin: an emerging player in the pathophysiology and treatment of depression? Published In The International Journal of Neuropsychopharmacology
  2016	The Neurodevelopmental Profile of Group 1 Metabotropic Glutamate Receptors: Implications for Novel Therapeutics Published In International Journal of Neuropsychopharmacology
  2015	Alterations of mGluR5 and its endogenous regulators Norbin, Tamalin and Preso1 in schizophrenia: towards a model of mGluR5 dysregulation Published In Acta Neuropathologica
  2015	Metabotropic glutamate receptor 5, and its trafficking molecules Norbin and Tamalin, are increased in the CA1 hippocampal region of subjects with schizophrenia Published In Schizophrenia Research
  2014	Negativity towards negative results: a discussion of the disconnect between scientific worth and scientific culture Published In Disease Models and Mechanisms

• Chapter

  Year	Title
  2014	Metabotropic glutamate receptor in the pathophysiology and treatment of schizophrenia and major depression Published In Metabotropic Glutamate Receptors: Molecular Mechanisms, Role in Neurological Disorders and Pharmacological Effects Publisher Now York

• Conference Paper

  Year	Title
  2016	Maternal fluoxetine treatment influences anxiety- and depressive-like behaviours in adolescent offspring: a rodent model Published In INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
  2016	Molecular Evidence of Synaptic Pathology in CA1 in Schizophrenia Published In BIOLOGICAL PSYCHIATRY
  2016	Norbin: an emerging player in the pathophysiology and treatment of depression? Published In INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
  2016	The Neurodevelopmental Profile of Group 1 Metabotropic Glutamate Receptors: Implications for Novel Therapeutics Published In INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
  2015	MGLUR5 dysregulation in schizophrenia and cognition: from gene to protein Published In JOURNAL OF NEUROCHEMISTRY
  2014	Alterations of mGluR5 and mGluR5 signaling partners in schizophrenia Published In Abstracts for 2014 Society for Neuroscience Annual Meeting
  2013	Subchronic metabotropic glutamate 5 receptor modulation in the perinatal pcp rodent model of schizophrenia Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants