Crook, Jeremy

Overview

Jeremy is Director of Biomedical Innovation at the Chris O'Brien Lifehouse Hospital, conjoint Arto Hardy Chair and Professor of Biomedical Innovation in the School of Medical Sciences at the University of Sydney (UOS), Chief Investigator for the Synthetic Biosystems theme of the ARC Centre of Excellence for Electromaterials Science, and Principal-Fellow at the University of Wollongong (UOW) and the Illawarra Health and Medical Research Institute (Hon).

Jeremy attained his Doctor of Philosophy (PhD - Medicine; NHMRC Postgraduate Scholarship awardee) at UOM followed by a US National Institutes of Health (NIH) Fogarty International Centre Fellowship. At NIH, Jeremy was awarded the NIH Fellows Award for Research Excellence (2001). From 2002-2007 Jeremy was Program Manager in the stem cell biotech ES Cell International (ESI), followed by Group Leader in Singapore’s A*STAR Institute of Medical Biology (IMB). At ESI and IMB Jeremy and his team developed the world’s first clinical-grade pluripotent stem cell lines for human therapies, including methods for clinically-compliant stem cell culture, scale-up and banking, with the cells and methods widely adopted and patented. Jeremy's contributions to human stem cell research also include seminal published guidances and standards for stem cell derivation, culture and differentiation, with the latter extending to pioneering neural cell modelling of neuropsychiatric disease. Jeremy’s experience in academia and industry, together with leading roles on international advisory boards and committees, including the International Society for Stem Cell Research (ISSCR) Standards Task Force, International Stem Cell Banking Initiative, UK Medical Research Council Molecular and Cellular Medicine Board Committee of Review, and Connecticut Academy of Science and Engineering Stem Cell Research Review Committee, puts him at the forefront of stem cell education and research both in Australia and abroad.

At UOW, Jeremy's team is making discoveries through next generation tissue building for drug and disease modelling, and regenerative medicine. Their research integrates front-line technologies stem cells, innovative biomaterials, 3D bioprinting and bioelectronics, and is establishing Australia’s position as a global leader in innovative tissue engineering and electroceuticals for advanced research and medicine.

As the Director of Biomedical Innovation at Chris O`Brien Lifehouse and conjoint Arto Hardy Family Chair and Professor of Biomedical Innovation at UOS Jeremy is extending his leadership in applied research, with a vision to accelerate biomedical advances within a clinical setting. An initial priority activity is collaborating with clinician researchers to further innovate electrical stimulation for advanced human tissue building and “within-body” electroceuticals for regenerative medicine and cancer therapeutics.

Top Publications

Year	Title
2019	Human Neural Tissues from Neural Stem Cells Using Conductive Biogel and Printed Polymer Microelectrode Arrays for 3D Electrical Stimulation Published in Advanced Healthcare Materials
2010	The generation of GLP-grade human embryonic stem cell banks from four clinical-grade cell lines for preclinical research Published in In Vitro Cellular and Developmental Biology: Animal
2017	3D Bioprinting Human Induced Pluripotent Stem Cell Constructs for In Situ Cell Proliferation and Successive Multilineage Differentiation Published in Advanced Healthcare Materials
2016	Functional 3D neural mini-tissues from printed gel-based bioink and human neural stem cells Published in Advanced Healthcare Materials
2015	Electrical stimulation using conductive polymer polypyrrole promotes differentiation of human neural stem cells: a biocompatible platform for translational neural tissue engineering Published in Tissue Engineering Part C: Methods
2010	Modelling disrupted-in-schizophrenia 1 loss of function in human neural progenitor cells: tools for molecular studies of human neurodevelopment and neuropsychiatric disorders Published in Molecular Psychiatry
2008	Attachment and growth of human embryonic stem cells on microcarriers Published in Journal of Biotechnology

Research Areas

Research Overview

Jeremy’s main current research interests are next-generation tissue building and electroceuticals (electric pharmaceuticals) for modelling development and disease, early phase drug discovery, and advanced medicine. His research integrates front-line technologies stem cells, organoidogenesis, cell-instructive bio- and electro-materials, 3D bioprinting and bioelectronics.

Geographic Focus

New South Wales State or Province

Available as Research Supervisor

Available for Collaborative Projects

Head Of

Chris O'Brien Lifehouse Hospital Director Biomedical Innovation 2021 -

Member Of

Asian-Pacific Society for Neurochemistry Member 2018 -
International Society for Neurochemistry Member 2018 -
Biological Psychiatry Australia Member 2010 -
Cell Reprogramming Australia Member 2010 -
Australasian Neuroscience Society Member 2009 -
Australian Society for Stem Cell Research Member 2009 -
International Society for Stem Cell Research Member 2006 -

Selected Publications

Journal Article

Year	Title
2022	Current and future perspectives on biomaterials for segmental mandibular defect repair Published In International Journal of Polymeric Materials and Polymeric Biomaterials
2021	A 3D printed graphene electrode device for enhanced and scalable stem cell culture, osteoinduction and tissue building Published In Materials and Design
2021	Bioengineering clinically relevant cardiomyocytes and cardiac tissues from pluripotent stem cells Published In International Journal of Molecular Sciences
2021	Engineering in vitro human neural tissue analogs by 3D bioprinting and electrostimulation Published In APL BIOENGINEERING
2021	Induced pluripotent stem cells for 2D and 3D modelling the biological basis of schizophrenia and screening possible therapeutics Published In Brain Research Bulletin
2020	3D graphene-containing structures for tissue engineering Published In Materials Today Chemistry
2020	Clinically amendable, defined, and rapid induction of human brain organoids from induced pluripotent stem cells Published In Methods in Molecular Biology
2020	Human Neural Tissues from Neural Stem Cells Using Conductive Biogel and Printed Polymer Microelectrode Arrays for 3D Electrical Stimulation Published In Advanced Healthcare Materials
2020	Neural Tissue Engineering: Human Neural Tissues from Neural Stem Cells Using Conductive Biogel and Printed Polymer Microelectrode Arrays for 3D Electrical Stimulation (Adv. Healthcare Mater. 15/2019) Published In Advanced Healthcare Materials
2020	Smart graphene-cellulose paper for 2D or 3D “origami-inspired” human stem cell support and differentiation Published In Colloids and Surfaces B: Biointerfaces
2020	3D Bioprinting Electrically Conductive Bioink with Human Neural Stem Cells for Human Neural Tissues Published In Methods in Molecular Biology
2020	3D Printing of Cytocompatible Graphene/Alginate Scaffolds for Mimetic Tissue Constructs Published In Frontiers in Bioengineering and Biotechnology
2020	Biomimetic corneal stroma using electro-compacted collagen Published In Acta Biomaterialia
2020	Bioprinting 3D Human Induced Pluripotent Stem Cell Constructs for Multilineage Tissue Engineering and Modeling
2020	Cell Processing for 3D Bioprinting: Quality Requirements for Quality Assurance in Fundamental Research and Translation
2020	Conducting Polymer Mediated Electrical Stimulation Induces Multilineage Differentiation with Robust Neuronal Fate Determination of Human Induced Pluripotent Stem Cells Published In Cells
2020	Electrical stimulation-induced osteogenesis of human adipose derived stem cells using a conductive graphene-cellulose scaffold Published In Materials Science and Engineering C: Materials for Biological Applications
2020	Molecular interactions and forces of adhesion between single human neural stem cells and gelatin methacrylate hydrogels of varying stiffness Published In Acta Biomaterialia
2020	Wet-Spun Trojan Horse Cell Constructs for Engineering Muscle Published In Frontiers in Chemistry
2019	3D graphene-containing structures for tissue engineering Published In Materials Today Chemistry
2019	Clinically amendable, defined, and rapid induction of human brain organoids from induced pluripotent stem cells Published In Methods in Molecular Biology
2019	Human Neural Tissues from Neural Stem Cells Using Conductive Biogel and Printed Polymer Microelectrode Arrays for 3D Electrical Stimulation Published In Advanced Healthcare Materials
2019	Neural Tissue Engineering: Human Neural Tissues from Neural Stem Cells Using Conductive Biogel and Printed Polymer Microelectrode Arrays for 3D Electrical Stimulation (Adv. Healthcare Mater. 15/2019) Published In Advanced Healthcare Materials
2019	Smart graphene-cellulose paper for 2D or 3D “origami-inspired” human stem cell support and differentiation Published In Colloids and Surfaces B: Biointerfaces
2018	A Standard Nomenclature for Referencing and Authentication of Pluripotent Stem Cells Published In Stem Cell Reports
2018	Biomaterials for corneal bioengineering Published In Biomedical Materials
2018	Conductive Polymers
2018	Conductive Tough Hydrogel for Bioapplications Published In Macromolecular Bioscience
2018	Three dimensional microenvironments on multi-electrode arrays produce neuronal networks that function like the brain Published In Frontiers in Cellular Neuroscience
2018	Three-dimensional neural cultures produce networks that mimic native brain activity Published In Journal of Tissue Engineering and Regenerative Medicine
2017	3D Bioprinting Human Induced Pluripotent Stem Cell Constructs for In Situ Cell Proliferation and Successive Multilineage Differentiation Published In Advanced Healthcare Materials
2017	Bioprinting: 3D Bioprinting Human Induced Pluripotent Stem Cell Constructs for In Situ Cell Proliferation and Successive Multilineage Differentiation (Adv. Healthcare Mater. 17/2017) Published In Advanced Healthcare Materials
2017	Development of a porous 3D graphene-PDMS scaffold for improved osseointegration Published In Colloids and Surfaces B: Biointerfaces
2017	Development of drug-loaded polymer microcapsules for treatment of epilepsy Published In Biomaterials Science
2017	Electrical stimulation using conductive polymer polypyrrole counters reduced neurite outgrowth of primary prefrontal cortical neurons from NRG1-KO and DISC1-LI mice Published In Scientific Reports
2017	Electro-mechano responsive properties of gelatin methacrylate (GelMA) hydrogel on conducting polymer electrodes quantified using atomic force microscopy Published In Soft Matter
2017	Report of the International Stem Cell Banking Initiative Workshop Activity: Current Hurdles and Progress in Seed-Stock Banking of Human Pluripotent Stem Cells Published In Stem Cells Translational Medicine
2016	Functional 3D neural mini-tissues from printed gel-based bioink and human neural stem cells Published In Advanced Healthcare Materials
2016	Stem Cell Bioprinting: Functional 3D Neural Mini-Tissues from Printed Gel-Based Bioink and Human Neural Stem Cells (Adv. Healthcare Mater. 12/2016) Published In Advanced Healthcare Materials
2015	Electrical stimulation using conductive polymer polypyrrole promotes differentiation of human neural stem cells: a biocompatible platform for translational neural tissue engineering Published In Tissue Engineering Part C: Methods
2015	Points to consider in the development of seed stocks of pluripotent stem cells for clinical applications: International Stem Cell Banking Initiative (ISCBI) Published In Regenerative Medicine
2015	Pre-differentiation of human neural stem cells into GABAergic neurons prior to transplant results in greater repopulation of the damaged brain and accelerates functional recovery after transient ischemic stroke Published In Stem Cell Research and Therapy
2015	The potential of induced pluripotent stem cells in models of neurological disorders: Implications on future therapy Published In Expert Review of Neurotherapeutics: a key contribution to decision making in the treatment of neurologic and neuropsychiatric disorders
2014	Differentiation of stem cells derived from human infrapatellar fat pad for cartilage engineering: characterisation of cells undergoing chondrogenesis Published In Tissue Engineering Part A
2013	Banking human induced pluripotent stem cells: lessons learned from embryonic stem cells? Published In Cell Stem Cell
2011	A call for standardized naming and reporting of human ESC and iPSC lines Published In Cell Stem Cell
2011	Human embryonic stem cell therapies for neurodegenerative diseases Published In CNS and Neurological Disorders
2011	Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage Published In Nature Biotechnology
2011	Toward clinical application of stem cells for cardiac regeneration Published In Heart Lung and Circulation
2010	Editorial [Human iPS Cells: Science and Ethics] Published In The Open Stem Cell Journal
2010	G-protein coupled receptors in stem cell self-renewal and differentiation Published In Stem Cell Reviews
2010	Modelling disrupted-in-schizophrenia 1 loss of function in human neural progenitor cells: tools for molecular studies of human neurodevelopment and neuropsychiatric disorders Published In Molecular Psychiatry
2010	Pluripotent human stem cells Published In BioDrugs: clinical immunotherapeutics, biopharmaceuticals and gene therapy
2010	The generation of GLP-grade human embryonic stem cell banks from four clinical-grade cell lines for preclinical research Published In In Vitro Cellular and Developmental Biology: Animal
2010	The international stem cell banking initiative (ISCBI): Raising standards to bank on Published In In Vitro Cellular and Developmental Biology - Animal
2009	Consensus Guidance for Banking and Supply of Human Embryonic Stem Cell Lines for Research Purposes Published In STEM CELL REVIEWS AND REPORTS
2009	Corrigendum to "Attachment and growth of human embryonic stem cells on microcarriers" [J. Biotechnol. 138 (2008) 24-32] (DOI:10.1016/j.jbiotec.2008.07.1997) Published In Journal of Biotechnology
2008	Attachment and growth of human embryonic stem cells on microcarriers Published In Journal of Biotechnology
2008	Efficient expansion of clinical-grade human fibroblasts on microcarriers: Cells suitable for ex vivo expansion of clinical-grade hESCs Published In Journal of Biotechnology
2008	Human stem cells for modeling neurological disorders: accelerating the drug discovery pipeline Published In Journal of Cellular Biochemistry
2008	Metabotropic glutamate receptor 2 and 3 gene expression in the human prefrontal cortex and mesencephalon in schizophrenia Published In International Journal of Neuroscience
2007	Schwann cells revert to non-myelinating phenotypes in the deafened rat cochlea Published In European Journal of Neuroscience
2007	The Generation of Six Clinical-Grade Human Embryonic Stem Cell Lines Published In Cell Stem Cell
2006	Fate of embryonic stem cells transplanted into the deafened mammalian cochlea Published In Cell Transplantation
2006	Human embryonic stem cells have a unique epigenetic signature Published In Genome Research
2006	Repressed by a NuRD Published In Nature Cell Biology
2005	Chronic depolarization enhances the trophic effects of brain-derived neurotrophic factor in rescuing auditory neurons following a sensorineural hearing loss Published In Journal of Comparative Neurology
2005	Genomic alterations in cultured human embryonic stem cells Published In Nature Genetics
2005	Netrin-1 as a guidance molecule in the postnatal rat cochlea Published In Hearing Research
2004	Karyotype of human ES cells during extended culture [3] (multiple letters) Published In Nature Biotechnology
2004	Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia Published In Proceedings of the National Academy of Sciences of the United States of America
2003	Cochlear immunochemistry - A new technique based on gelatin embedding Published In Journal of Neuroscience Methods
2002	Comparative analysis of group II metabotropic glutamate receptor immunoreactivity in Brodmann's area 46 of the dorsolateral prefrontal cortex from patients with schizophrenia and normal subjects Published In Molecular Psychiatry
2002	Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: A preliminary study Published In Schizophrenia Research
2001	Cholinergic systems and schizophrenia: Primary pathology or epiphenomena? Published In Journal of Chemical Neuroanatomy
2000	136. Muscarinic receptor protein and mRNA in DLPFC of schizophrenia and affective disorder Published In Biological Psychiatry
2000	Biological Markers and Schizophrenia Published In Australian and New Zealand Journal of Psychiatry
2000	Biological Markers and Schizophrenia Published In Australian & New Zealand Journal of Psychiatry
2000	Muscarinic1 and 2 receptor mRNA in the human caudate-putamen: No change in m1 mRNA in schizophrenia Published In Molecular Psychiatry
1999	The binding of [³H]AF-DX 384 is reduced in the caudate-putamen of subjects with schizophrenia Published In Life Sciences
1997	80 Muscarinic M1 receptors in the caudate putamen of patients with schizophrenia: Decreased receptor density is not accompanied by decreased receptor rnRNA Published In Schizophrenia Research
1996	The density of muscarinic M1 receptors is decreased in the caudate-putamen of subjects with schizophrenia Published In Molecular Psychiatry

Book

Year	Title
2020	Preface

Chapter

Year	Title
2020	Chapter 7 Electroceuticals for neural regenerative nanomedicine Published In Neural Regenerative Nanomedicine Publisher Elsevier
2018	Engineering human neural tissue by 3D bioprinting Published In Biomaterials for tissue engineering: methods and protocols Publisher United States
2017	Cryobanking Pluripotent Stem Cells Published In Stem Cell Banking: Concepts and Protocols Publisher New York, United States
2017	Culturing and Cryobanking Human Neural Stem Cells Published In Stem Cell Banking: Concepts and Protocols Publisher New York, United States
2017	Derivation of Human Embryonic Stem Cells Published In Stem Cell Banking: Concepts and Protocols Publisher New York, United States
2017	The role of electrical field on stem cells in vitro Published In Conductive Polymers: Electrical Interactions in Cell Biology and Medicine Publisher New York
2014	Setting quality standards for stem cell banking, research and translation: the international stem cell banking initiative Published In Stem Cell Banking Publisher United States
2012	Biobanks for pluripotent stem cells Published In Human Stem Cell Manual: A Laboratory Guide Publisher United Kingdom
2012	Chapter 8 Biobanks for Pluripotent Stem Cells Published In Human Stem Cell Manual Publisher Elsevier
2010	Differentiation of Pluripotent Stem Cells: An Overview Published In Human Stem Cell Technology and Biology: A Research Guide and Laboratory Manual Publisher John Wiley & Sons, Inc.
2007	Expansion of undifferentiated human embryonic stem cells Published In CELL TECHNOLOGY FOR CELL PRODUCTS Publisher SPRINGER
2007	Standard Culture of Human Embryonic Stem Cells Published In Human Embryonic Stem Cells: The Practical Handbook Publisher John Wiley & Sons, Ltd

Conference Paper

Year	Title
2018	DELIVERY OF MUSCLE PROGENITOR CELLS BY TROJAN HORSE MICROTISSUE CONSTRUCTS: TOWARDS AUTOLOGOUS REGENERATIVE CELL THERAPIES FOR MUSCLE DISEASE Published In JOURNAL OF GENE MEDICINE
2018	STUDYING THE BRAIN WITHOUT STUDYING THE BRAIN: 3D NEURAL TISSUE CONSTRUCTS FROM HUMAN IPSCS Published In JOURNAL OF GENE MEDICINE
2001	Gene expression of group II metabotropic glutamate receptors in the prefrontal cortex of schizophrenic subjects and controls Published In BIOLOGICAL PSYCHIATRY
2000	Extraction of total RNA in human brain post-mortem tissue: Effect of diagnosis on RNA yield Published In BIOLOGICAL PSYCHIATRY
2000	In vivo and in vitro evidence of induced muscarinic receptor availability in schizophrenia in patients. Published In JOURNAL OF NUCLEAR MEDICINE

Other Publications

Year	Title
2020	A Report from a Workshop of the International Stem Cell Banking Initiative, Held in Collaboration of Global Alliance for iPSC Therapies and the Harvard Stem Cell Institute, Boston, 2017
2019	A Report from a Workshop of the International Stem Cell Banking Initiative, Held in Collaboration of Global Alliance for iPSC Therapies and the Harvard Stem Cell Institute, Boston, 2017

Editor Of

Featured In

The Illawarra Mercury Article

Investigator On

Year	Title
2021 - 2024	A wireless electric nerve-guide for peripheral nerve repair Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Ideas Grant
2022	Micro-electrofluidic platforms for monitoring 3D human biological models Awarded by: Australian Research Council (ARC) Funding Scheme: Discovery Projects
2020	MedTech Actuator Menzies Fellowship 2021 Awarded by: Menzies Foundation Funding Scheme: MedTech Actuator Menzies Fellowship
2014 - 2020	ARC Centre of Excellence for Electromaterials Science Awarded by: Australian Research Council (ARC) Funding Scheme: Centres of Excellence
2018	3D Additive Bio-Fabrication Facility: Printing Bioprinters Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2018	Electrophysiology Facility for Cell Phenotyping and Drug Discovery Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2018	Forced exercise/walking wheel system for rats Model 80805A Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2014 - 2017	Application of intelligent conducting polymers for treating schizophrenia and allied disorders focusing on neuronal outgrowth, myelination and synaptogenesis Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
	Quarantined Ion Chromatography - Mass Spectrometry Facility Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
	Rat activity wheel and living chamber system Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant

Other Research Activities

MedTech Actuator Menzies Fellowship MedTech Actuator Menzies Fellow 2021
Global Challenges Funding Award: Modelling emergent properties in the brain to combat neurodegenerative disease Named Investigator 2019 - 2020
ANSTO-UOW Joint Project Seed Funding Award: Chief Investigator –Testing in vivo biocompatibility and osteoinductivity of a 3D graphene scaffold for bone regeneration Chief Investigator 2018 - 2020
ANSTO-UOW Joint Project Seed Funding Award: In vivo imaging of 3D neural microtissues Chief Investigator 2016 - 2017
Dyason Fellowship - University of Melbourne Dyason Fellow 2012
Leadership Fellowship in Stem Cell Medicine – Helen Macpherson Smith Trust & O’Brien Foundation Director 2010 - 2012
NHMRC Project Grant 628767: Free radicals in Brain Repair After Stroke Chief Investigator 2010 - 2012
National Heart Foundation Grant In Aid G09M4399: Tissue Engineering Of Human Cardiac Muscle From Autologous Stem Cells Chief Investigator 2010 - 2011

Impact Story

Available as Research Supervisor

Potential Supervision Topics

Broadly, next generation human tissue building and electroceuticals using front-line technologies stem cells, innovative biomaterials, 3D bioprinting, organoidogenesis and bioelectronics.

Teaching Activities

University of Technology Sydney - Engineering 42026 Biomedical Polymers: Polymers for Neural Regeneration Guest Lecturer 2020 -
AIIM901 Online Biofabrication Course Subject Developer & Facilitator - "Brain On The Bench" 2019 -
Sydney University - AMME4971/AMME9971 Tissue Engineering: Synthetic Biosystems For 3D Modelling Of Development, Disease & Regenerative Medicine Guest Lecturer 2018 -
University of Wollongong MEDI400 Medical and Health Science Honours, School of Medicine Honours Program Student Supervisor 2017 -

Advisees

Graduate Advising Relationship

Degree	Research Title	Advisee
Doctor of Philosophy	Electro Stimulation of 3D Bioprinted Neural Tissues	Warren, Danielle
Doctor of Philosophy	Direct Piezoelectricity for 3D Cardiac Tissue Engineering and Remodelling	James, Emma
Doctor of Philosophy	Therapeutic effects of electrical stimulation on a human vascularised cerebral organoid-paediatric high-grade giloma model	Higginbottom, Sarah
Doctor of Philosophy	Electrifying 3D Human Neural Tissues for Enhanced Pharmacotherapy	Jay, Sky
Doctor of Philosophy	Development of a Cell-Laden Electric Nerve Guidance Conduit	Mohammadi, Mohammad

Outreach Overview

To inspire and educate the public by targeted communication about our frontier research undertaken at the University of Wollongong.

Recent media outreach includes:

1. https://researchaustralia.org/congratulations-to-the-winner-of-the-frontiers-researchaward-
jeremy-crook-and-team/

2. https://researchaustralia.org/category/news/media/

3. https://www.illawarramercury.com.au/story/6487387/uow-scientists-electrifying-discoveryand-the-conditions-it-could-help/

4. See p8 of Research Australia's INSPIRE Magazine Issue 14: https://issuu.com/researchaustralia/docs/ra0026_inspire_dec19__

5. ACES News: https://electromaterials.edu.au/2019/06/28/prof-jeremy-crook-on-groundbreaking-stem-cell-research-findings/

6. ABC Catalyst Bionic Revolution (from 47 minute mark): https://www.abc.net.au/catalyst/bionic-revolution/11017392

7. Kids News: https://www.kidsnews.com.au/science/australian-scientists-have-grown-minibrains-and-zapped-them-to-life-with-electricity/newsstory/451779e60c2e942553ae06d3ca1f1df0

8. Brigid OConnell: https://twitter.com/BrigidOConnell/status/1202356508882636803

9. Herald Sun: https://www.heraldsun.com.au/subscribe/news/1/?sourceCode=HSWEB_WRE170_a_TWT&dest=https%3A%2F%2Fwww.heraldsun.com.au%2Fnews%2Fvictoria%2Funiversity-ofwollongong-scientists-present-mini-brains-technology%2Fnewsstory%2F960de8f80c166f3e3c4e3b413de53f7f&memtype=anonymous&mode=premium

10. Australasian Neuroscience Society: https://twitter.com/AusNeuroSoc/status/1202423989726892032?s=20

11. Cellink Life Sciences: https://www.cellink.com/close-3d-printing-bodies/

12. ABC News: https://www.abc.net.au/news/science/2017-07-26/scientists-create-3d-printedbrain-like-tissue-from-stem-cells/8740794

13. Advanced Science News: http://www.advancedsciencenews.com/

Education And Training

B.Sc., University of Tasmania, Honours
Ph.D., University of Melbourne, Department of Pathology 1998

Awards And Honors

2021 MedTech Actuator Menzies Fellowship, conferred by MedTech Actuator and Menzies Foundation , 2020
Inaugural Research Australia 2019 Health and Medical Research “Frontiers Research Award”, conferred by Research Australia, 2019
Acknowledgement Letter - Outstanding Student Supervisor , conferred by China Scholarship Council., 2018
Dyason Fellowship , conferred by The University of Melbourne, 2013
Young Investigator Award , conferred by International Congress on Schizophrenia Research, 2001
NIH Fellows Award for Research Excellence , conferred by US National Institutes of Health, 2001
Fogarty International Center Medical Research Fellowship , conferred by Fogarty International Center, National Institutes of Health, 1999
NHMRC “Dora Lush" Postgraduate Research Scholarship, conferred by NHMRC, 1994 - 1998

Teaching Overview

Jeremy is utilising his expertise and research discoveries to provide high-quality interdisciplinary undergraduate and graduate student research training. Training broadly relates to applying new bio- and elecro-material-based strategies (with additive manufacturing) to improve cell delivery and quality of engineered tissues, and attendant bioelectronic devices for clinical application.

Keywords

1. stem cells, 2. neurodevelopmental disorders, 3. tissue engineering, 4. neural regulation, 5. disease modelling, 6. cellular mechanisms, 7. disease mechanisms, 8. neuropsychiatric disorders, 9. neurogenesis, 10. biomaterials, 11. electromaterials, 12. bioelectronics, 13. electroceuticals

Full Name

Jeremy Micah Crook

Mailing Address

Squires Way, AIIM Facility, Innovation Campus

Fairy Meadow

NSW

2519

Austrralia

Located In Facility

Intelligent Polymer Research Institute

Orcid Id

http://orcid.org/0000-0002-6415-1639 (confirmed)

Web Of Science Researcher Id

AAH-8441-2020

Scopus Id

7103400432

Top Publications

Year	Title
2019	Human Neural Tissues from Neural Stem Cells Using Conductive Biogel and Printed Polymer Microelectrode Arrays for 3D Electrical Stimulation Published in Advanced Healthcare Materials
2010	The generation of GLP-grade human embryonic stem cell banks from four clinical-grade cell lines for preclinical research Published in In Vitro Cellular and Developmental Biology: Animal
2017	3D Bioprinting Human Induced Pluripotent Stem Cell Constructs for In Situ Cell Proliferation and Successive Multilineage Differentiation Published in Advanced Healthcare Materials
2016	Functional 3D neural mini-tissues from printed gel-based bioink and human neural stem cells Published in Advanced Healthcare Materials
2015	Electrical stimulation using conductive polymer polypyrrole promotes differentiation of human neural stem cells: a biocompatible platform for translational neural tissue engineering Published in Tissue Engineering Part C: Methods
2010	Modelling disrupted-in-schizophrenia 1 loss of function in human neural progenitor cells: tools for molecular studies of human neurodevelopment and neuropsychiatric disorders Published in Molecular Psychiatry
2008	Attachment and growth of human embryonic stem cells on microcarriers Published in Journal of Biotechnology

Research Areas

Research Overview

Jeremy’s main current research interests are next-generation tissue building and electroceuticals (electric pharmaceuticals) for modelling development and disease, early phase drug discovery, and advanced medicine. His research integrates front-line technologies stem cells, organoidogenesis, cell-instructive bio- and electro-materials, 3D bioprinting and bioelectronics.

Geographic Focus

New South Wales State or Province

Head Of

Chris O'Brien Lifehouse Hospital Director Biomedical Innovation 2021 -

Member Of

Asian-Pacific Society for Neurochemistry Member 2018 -
International Society for Neurochemistry Member 2018 -
Biological Psychiatry Australia Member 2010 -
Cell Reprogramming Australia Member 2010 -
Australasian Neuroscience Society Member 2009 -
Australian Society for Stem Cell Research Member 2009 -
International Society for Stem Cell Research Member 2006 -

Selected Publications

Journal Article

Year	Title
2022	Current and future perspectives on biomaterials for segmental mandibular defect repair Published In International Journal of Polymeric Materials and Polymeric Biomaterials
2021	A 3D printed graphene electrode device for enhanced and scalable stem cell culture, osteoinduction and tissue building Published In Materials and Design
2021	Bioengineering clinically relevant cardiomyocytes and cardiac tissues from pluripotent stem cells Published In International Journal of Molecular Sciences
2021	Engineering in vitro human neural tissue analogs by 3D bioprinting and electrostimulation Published In APL BIOENGINEERING
2021	Induced pluripotent stem cells for 2D and 3D modelling the biological basis of schizophrenia and screening possible therapeutics Published In Brain Research Bulletin
2020	3D graphene-containing structures for tissue engineering Published In Materials Today Chemistry
2020	Clinically amendable, defined, and rapid induction of human brain organoids from induced pluripotent stem cells Published In Methods in Molecular Biology
2020	Human Neural Tissues from Neural Stem Cells Using Conductive Biogel and Printed Polymer Microelectrode Arrays for 3D Electrical Stimulation Published In Advanced Healthcare Materials
2020	Neural Tissue Engineering: Human Neural Tissues from Neural Stem Cells Using Conductive Biogel and Printed Polymer Microelectrode Arrays for 3D Electrical Stimulation (Adv. Healthcare Mater. 15/2019) Published In Advanced Healthcare Materials
2020	Smart graphene-cellulose paper for 2D or 3D “origami-inspired” human stem cell support and differentiation Published In Colloids and Surfaces B: Biointerfaces
2020	3D Bioprinting Electrically Conductive Bioink with Human Neural Stem Cells for Human Neural Tissues Published In Methods in Molecular Biology
2020	3D Printing of Cytocompatible Graphene/Alginate Scaffolds for Mimetic Tissue Constructs Published In Frontiers in Bioengineering and Biotechnology
2020	Biomimetic corneal stroma using electro-compacted collagen Published In Acta Biomaterialia
2020	Bioprinting 3D Human Induced Pluripotent Stem Cell Constructs for Multilineage Tissue Engineering and Modeling
2020	Cell Processing for 3D Bioprinting: Quality Requirements for Quality Assurance in Fundamental Research and Translation
2020	Conducting Polymer Mediated Electrical Stimulation Induces Multilineage Differentiation with Robust Neuronal Fate Determination of Human Induced Pluripotent Stem Cells Published In Cells
2020	Electrical stimulation-induced osteogenesis of human adipose derived stem cells using a conductive graphene-cellulose scaffold Published In Materials Science and Engineering C: Materials for Biological Applications
2020	Molecular interactions and forces of adhesion between single human neural stem cells and gelatin methacrylate hydrogels of varying stiffness Published In Acta Biomaterialia
2020	Wet-Spun Trojan Horse Cell Constructs for Engineering Muscle Published In Frontiers in Chemistry
2019	3D graphene-containing structures for tissue engineering Published In Materials Today Chemistry
2019	Clinically amendable, defined, and rapid induction of human brain organoids from induced pluripotent stem cells Published In Methods in Molecular Biology
2019	Human Neural Tissues from Neural Stem Cells Using Conductive Biogel and Printed Polymer Microelectrode Arrays for 3D Electrical Stimulation Published In Advanced Healthcare Materials
2019	Neural Tissue Engineering: Human Neural Tissues from Neural Stem Cells Using Conductive Biogel and Printed Polymer Microelectrode Arrays for 3D Electrical Stimulation (Adv. Healthcare Mater. 15/2019) Published In Advanced Healthcare Materials
2019	Smart graphene-cellulose paper for 2D or 3D “origami-inspired” human stem cell support and differentiation Published In Colloids and Surfaces B: Biointerfaces
2018	A Standard Nomenclature for Referencing and Authentication of Pluripotent Stem Cells Published In Stem Cell Reports
2018	Biomaterials for corneal bioengineering Published In Biomedical Materials
2018	Conductive Polymers
2018	Conductive Tough Hydrogel for Bioapplications Published In Macromolecular Bioscience
2018	Three dimensional microenvironments on multi-electrode arrays produce neuronal networks that function like the brain Published In Frontiers in Cellular Neuroscience
2018	Three-dimensional neural cultures produce networks that mimic native brain activity Published In Journal of Tissue Engineering and Regenerative Medicine
2017	3D Bioprinting Human Induced Pluripotent Stem Cell Constructs for In Situ Cell Proliferation and Successive Multilineage Differentiation Published In Advanced Healthcare Materials
2017	Bioprinting: 3D Bioprinting Human Induced Pluripotent Stem Cell Constructs for In Situ Cell Proliferation and Successive Multilineage Differentiation (Adv. Healthcare Mater. 17/2017) Published In Advanced Healthcare Materials
2017	Development of a porous 3D graphene-PDMS scaffold for improved osseointegration Published In Colloids and Surfaces B: Biointerfaces
2017	Development of drug-loaded polymer microcapsules for treatment of epilepsy Published In Biomaterials Science
2017	Electrical stimulation using conductive polymer polypyrrole counters reduced neurite outgrowth of primary prefrontal cortical neurons from NRG1-KO and DISC1-LI mice Published In Scientific Reports
2017	Electro-mechano responsive properties of gelatin methacrylate (GelMA) hydrogel on conducting polymer electrodes quantified using atomic force microscopy Published In Soft Matter
2017	Report of the International Stem Cell Banking Initiative Workshop Activity: Current Hurdles and Progress in Seed-Stock Banking of Human Pluripotent Stem Cells Published In Stem Cells Translational Medicine
2016	Functional 3D neural mini-tissues from printed gel-based bioink and human neural stem cells Published In Advanced Healthcare Materials
2016	Stem Cell Bioprinting: Functional 3D Neural Mini-Tissues from Printed Gel-Based Bioink and Human Neural Stem Cells (Adv. Healthcare Mater. 12/2016) Published In Advanced Healthcare Materials
2015	Electrical stimulation using conductive polymer polypyrrole promotes differentiation of human neural stem cells: a biocompatible platform for translational neural tissue engineering Published In Tissue Engineering Part C: Methods
2015	Points to consider in the development of seed stocks of pluripotent stem cells for clinical applications: International Stem Cell Banking Initiative (ISCBI) Published In Regenerative Medicine
2015	Pre-differentiation of human neural stem cells into GABAergic neurons prior to transplant results in greater repopulation of the damaged brain and accelerates functional recovery after transient ischemic stroke Published In Stem Cell Research and Therapy
2015	The potential of induced pluripotent stem cells in models of neurological disorders: Implications on future therapy Published In Expert Review of Neurotherapeutics: a key contribution to decision making in the treatment of neurologic and neuropsychiatric disorders
2014	Differentiation of stem cells derived from human infrapatellar fat pad for cartilage engineering: characterisation of cells undergoing chondrogenesis Published In Tissue Engineering Part A
2013	Banking human induced pluripotent stem cells: lessons learned from embryonic stem cells? Published In Cell Stem Cell
2011	A call for standardized naming and reporting of human ESC and iPSC lines Published In Cell Stem Cell
2011	Human embryonic stem cell therapies for neurodegenerative diseases Published In CNS and Neurological Disorders
2011	Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage Published In Nature Biotechnology
2011	Toward clinical application of stem cells for cardiac regeneration Published In Heart Lung and Circulation
2010	Editorial [Human iPS Cells: Science and Ethics] Published In The Open Stem Cell Journal
2010	G-protein coupled receptors in stem cell self-renewal and differentiation Published In Stem Cell Reviews
2010	Modelling disrupted-in-schizophrenia 1 loss of function in human neural progenitor cells: tools for molecular studies of human neurodevelopment and neuropsychiatric disorders Published In Molecular Psychiatry
2010	Pluripotent human stem cells Published In BioDrugs: clinical immunotherapeutics, biopharmaceuticals and gene therapy
2010	The generation of GLP-grade human embryonic stem cell banks from four clinical-grade cell lines for preclinical research Published In In Vitro Cellular and Developmental Biology: Animal
2010	The international stem cell banking initiative (ISCBI): Raising standards to bank on Published In In Vitro Cellular and Developmental Biology - Animal
2009	Consensus Guidance for Banking and Supply of Human Embryonic Stem Cell Lines for Research Purposes Published In STEM CELL REVIEWS AND REPORTS
2009	Corrigendum to "Attachment and growth of human embryonic stem cells on microcarriers" [J. Biotechnol. 138 (2008) 24-32] (DOI:10.1016/j.jbiotec.2008.07.1997) Published In Journal of Biotechnology
2008	Attachment and growth of human embryonic stem cells on microcarriers Published In Journal of Biotechnology
2008	Efficient expansion of clinical-grade human fibroblasts on microcarriers: Cells suitable for ex vivo expansion of clinical-grade hESCs Published In Journal of Biotechnology
2008	Human stem cells for modeling neurological disorders: accelerating the drug discovery pipeline Published In Journal of Cellular Biochemistry
2008	Metabotropic glutamate receptor 2 and 3 gene expression in the human prefrontal cortex and mesencephalon in schizophrenia Published In International Journal of Neuroscience
2007	Schwann cells revert to non-myelinating phenotypes in the deafened rat cochlea Published In European Journal of Neuroscience
2007	The Generation of Six Clinical-Grade Human Embryonic Stem Cell Lines Published In Cell Stem Cell
2006	Fate of embryonic stem cells transplanted into the deafened mammalian cochlea Published In Cell Transplantation
2006	Human embryonic stem cells have a unique epigenetic signature Published In Genome Research
2006	Repressed by a NuRD Published In Nature Cell Biology
2005	Chronic depolarization enhances the trophic effects of brain-derived neurotrophic factor in rescuing auditory neurons following a sensorineural hearing loss Published In Journal of Comparative Neurology
2005	Genomic alterations in cultured human embryonic stem cells Published In Nature Genetics
2005	Netrin-1 as a guidance molecule in the postnatal rat cochlea Published In Hearing Research
2004	Karyotype of human ES cells during extended culture [3] (multiple letters) Published In Nature Biotechnology
2004	Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia Published In Proceedings of the National Academy of Sciences of the United States of America
2003	Cochlear immunochemistry - A new technique based on gelatin embedding Published In Journal of Neuroscience Methods
2002	Comparative analysis of group II metabotropic glutamate receptor immunoreactivity in Brodmann's area 46 of the dorsolateral prefrontal cortex from patients with schizophrenia and normal subjects Published In Molecular Psychiatry
2002	Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: A preliminary study Published In Schizophrenia Research
2001	Cholinergic systems and schizophrenia: Primary pathology or epiphenomena? Published In Journal of Chemical Neuroanatomy
2000	136. Muscarinic receptor protein and mRNA in DLPFC of schizophrenia and affective disorder Published In Biological Psychiatry
2000	Biological Markers and Schizophrenia Published In Australian and New Zealand Journal of Psychiatry
2000	Biological Markers and Schizophrenia Published In Australian & New Zealand Journal of Psychiatry
2000	Muscarinic1 and 2 receptor mRNA in the human caudate-putamen: No change in m1 mRNA in schizophrenia Published In Molecular Psychiatry
1999	The binding of [³H]AF-DX 384 is reduced in the caudate-putamen of subjects with schizophrenia Published In Life Sciences
1997	80 Muscarinic M1 receptors in the caudate putamen of patients with schizophrenia: Decreased receptor density is not accompanied by decreased receptor rnRNA Published In Schizophrenia Research
1996	The density of muscarinic M1 receptors is decreased in the caudate-putamen of subjects with schizophrenia Published In Molecular Psychiatry

Book

Year	Title
2020	Preface

Chapter

Year	Title
2020	Chapter 7 Electroceuticals for neural regenerative nanomedicine Published In Neural Regenerative Nanomedicine Publisher Elsevier
2018	Engineering human neural tissue by 3D bioprinting Published In Biomaterials for tissue engineering: methods and protocols Publisher United States
2017	Cryobanking Pluripotent Stem Cells Published In Stem Cell Banking: Concepts and Protocols Publisher New York, United States
2017	Culturing and Cryobanking Human Neural Stem Cells Published In Stem Cell Banking: Concepts and Protocols Publisher New York, United States
2017	Derivation of Human Embryonic Stem Cells Published In Stem Cell Banking: Concepts and Protocols Publisher New York, United States
2017	The role of electrical field on stem cells in vitro Published In Conductive Polymers: Electrical Interactions in Cell Biology and Medicine Publisher New York
2014	Setting quality standards for stem cell banking, research and translation: the international stem cell banking initiative Published In Stem Cell Banking Publisher United States
2012	Biobanks for pluripotent stem cells Published In Human Stem Cell Manual: A Laboratory Guide Publisher United Kingdom
2012	Chapter 8 Biobanks for Pluripotent Stem Cells Published In Human Stem Cell Manual Publisher Elsevier
2010	Differentiation of Pluripotent Stem Cells: An Overview Published In Human Stem Cell Technology and Biology: A Research Guide and Laboratory Manual Publisher John Wiley & Sons, Inc.
2007	Expansion of undifferentiated human embryonic stem cells Published In CELL TECHNOLOGY FOR CELL PRODUCTS Publisher SPRINGER
2007	Standard Culture of Human Embryonic Stem Cells Published In Human Embryonic Stem Cells: The Practical Handbook Publisher John Wiley & Sons, Ltd

Conference Paper

Year	Title
2018	DELIVERY OF MUSCLE PROGENITOR CELLS BY TROJAN HORSE MICROTISSUE CONSTRUCTS: TOWARDS AUTOLOGOUS REGENERATIVE CELL THERAPIES FOR MUSCLE DISEASE Published In JOURNAL OF GENE MEDICINE
2018	STUDYING THE BRAIN WITHOUT STUDYING THE BRAIN: 3D NEURAL TISSUE CONSTRUCTS FROM HUMAN IPSCS Published In JOURNAL OF GENE MEDICINE
2001	Gene expression of group II metabotropic glutamate receptors in the prefrontal cortex of schizophrenic subjects and controls Published In BIOLOGICAL PSYCHIATRY
2000	Extraction of total RNA in human brain post-mortem tissue: Effect of diagnosis on RNA yield Published In BIOLOGICAL PSYCHIATRY
2000	In vivo and in vitro evidence of induced muscarinic receptor availability in schizophrenia in patients. Published In JOURNAL OF NUCLEAR MEDICINE

Other Publications

Year	Title
2020	A Report from a Workshop of the International Stem Cell Banking Initiative, Held in Collaboration of Global Alliance for iPSC Therapies and the Harvard Stem Cell Institute, Boston, 2017
2019	A Report from a Workshop of the International Stem Cell Banking Initiative, Held in Collaboration of Global Alliance for iPSC Therapies and the Harvard Stem Cell Institute, Boston, 2017

Editor Of

Featured In

The Illawarra Mercury Article

Investigator On

Year	Title
2021 - 2024	A wireless electric nerve-guide for peripheral nerve repair Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Ideas Grant
2022	Micro-electrofluidic platforms for monitoring 3D human biological models Awarded by: Australian Research Council (ARC) Funding Scheme: Discovery Projects
2020	MedTech Actuator Menzies Fellowship 2021 Awarded by: Menzies Foundation Funding Scheme: MedTech Actuator Menzies Fellowship
2014 - 2020	ARC Centre of Excellence for Electromaterials Science Awarded by: Australian Research Council (ARC) Funding Scheme: Centres of Excellence
2018	3D Additive Bio-Fabrication Facility: Printing Bioprinters Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2018	Electrophysiology Facility for Cell Phenotyping and Drug Discovery Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2018	Forced exercise/walking wheel system for rats Model 80805A Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2014 - 2017	Application of intelligent conducting polymers for treating schizophrenia and allied disorders focusing on neuronal outgrowth, myelination and synaptogenesis Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
	Quarantined Ion Chromatography - Mass Spectrometry Facility Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
	Rat activity wheel and living chamber system Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant

Other Research Activities

MedTech Actuator Menzies Fellowship MedTech Actuator Menzies Fellow 2021
Global Challenges Funding Award: Modelling emergent properties in the brain to combat neurodegenerative disease Named Investigator 2019 - 2020
ANSTO-UOW Joint Project Seed Funding Award: Chief Investigator –Testing in vivo biocompatibility and osteoinductivity of a 3D graphene scaffold for bone regeneration Chief Investigator 2018 - 2020
ANSTO-UOW Joint Project Seed Funding Award: In vivo imaging of 3D neural microtissues Chief Investigator 2016 - 2017
Dyason Fellowship - University of Melbourne Dyason Fellow 2012
Leadership Fellowship in Stem Cell Medicine – Helen Macpherson Smith Trust & O’Brien Foundation Director 2010 - 2012
NHMRC Project Grant 628767: Free radicals in Brain Repair After Stroke Chief Investigator 2010 - 2012
National Heart Foundation Grant In Aid G09M4399: Tissue Engineering Of Human Cardiac Muscle From Autologous Stem Cells Chief Investigator 2010 - 2011

Impact Story

Potential Supervision Topics

Broadly, next generation human tissue building and electroceuticals using front-line technologies stem cells, innovative biomaterials, 3D bioprinting, organoidogenesis and bioelectronics.

Teaching Activities

University of Technology Sydney - Engineering 42026 Biomedical Polymers: Polymers for Neural Regeneration Guest Lecturer 2020 -
AIIM901 Online Biofabrication Course Subject Developer & Facilitator - "Brain On The Bench" 2019 -
Sydney University - AMME4971/AMME9971 Tissue Engineering: Synthetic Biosystems For 3D Modelling Of Development, Disease & Regenerative Medicine Guest Lecturer 2018 -
University of Wollongong MEDI400 Medical and Health Science Honours, School of Medicine Honours Program Student Supervisor 2017 -

Advisees

Graduate Advising Relationship

Degree	Research Title	Advisee
Doctor of Philosophy	Electro Stimulation of 3D Bioprinted Neural Tissues	Warren, Danielle
Doctor of Philosophy	Direct Piezoelectricity for 3D Cardiac Tissue Engineering and Remodelling	James, Emma
Doctor of Philosophy	Therapeutic effects of electrical stimulation on a human vascularised cerebral organoid-paediatric high-grade giloma model	Higginbottom, Sarah
Doctor of Philosophy	Electrifying 3D Human Neural Tissues for Enhanced Pharmacotherapy	Jay, Sky
Doctor of Philosophy	Development of a Cell-Laden Electric Nerve Guidance Conduit	Mohammadi, Mohammad

Outreach Overview

To inspire and educate the public by targeted communication about our frontier research undertaken at the University of Wollongong.

Recent media outreach includes:

1. https://researchaustralia.org/congratulations-to-the-winner-of-the-frontiers-researchaward-
jeremy-crook-and-team/

2. https://researchaustralia.org/category/news/media/

3. https://www.illawarramercury.com.au/story/6487387/uow-scientists-electrifying-discoveryand-the-conditions-it-could-help/

4. See p8 of Research Australia's INSPIRE Magazine Issue 14: https://issuu.com/researchaustralia/docs/ra0026_inspire_dec19__

5. ACES News: https://electromaterials.edu.au/2019/06/28/prof-jeremy-crook-on-groundbreaking-stem-cell-research-findings/

6. ABC Catalyst Bionic Revolution (from 47 minute mark): https://www.abc.net.au/catalyst/bionic-revolution/11017392

7. Kids News: https://www.kidsnews.com.au/science/australian-scientists-have-grown-minibrains-and-zapped-them-to-life-with-electricity/newsstory/451779e60c2e942553ae06d3ca1f1df0

8. Brigid OConnell: https://twitter.com/BrigidOConnell/status/1202356508882636803

9. Herald Sun: https://www.heraldsun.com.au/subscribe/news/1/?sourceCode=HSWEB_WRE170_a_TWT&dest=https%3A%2F%2Fwww.heraldsun.com.au%2Fnews%2Fvictoria%2Funiversity-ofwollongong-scientists-present-mini-brains-technology%2Fnewsstory%2F960de8f80c166f3e3c4e3b413de53f7f&memtype=anonymous&mode=premium

10. Australasian Neuroscience Society: https://twitter.com/AusNeuroSoc/status/1202423989726892032?s=20

11. Cellink Life Sciences: https://www.cellink.com/close-3d-printing-bodies/

12. ABC News: https://www.abc.net.au/news/science/2017-07-26/scientists-create-3d-printedbrain-like-tissue-from-stem-cells/8740794

13. Advanced Science News: http://www.advancedsciencenews.com/

Reviewer Of

3D Bioprinting: Principles and Protocols; Methods in Molecular Biology; Springer Nature (Edited Book) 2020 -
Associate Editor: 'Experimental Therapeutics' section of Frontiers in Neurology (Journal) 2020 -
Editorial Board Member: Bioprinting (Journal) 2018 -
Stem Cell Banking: Concepts & Protocols; Methods in Molecular Biology. Springer Nature (Edited Book) 2017 -
Editorial Board Member: BioEssays (Journal) 2016 -
Editorial Board Member: The Open Medicine Journal (Journal) 2015 -
Editorial Board Member: Data Set Papers in Medicine - Psychiatry (Journal) 2012 -
Editorial Board Member: Journal of Cellular Biochemistry (Journal) 2009 -
Editorial Board Member: World Stem Cell Journal (Journal) 2009 -
Editorial Board Member: Scientifica (Journal) 2012 - 2017
Editorial Board Member: Inside the Cell (Journal) 2014 - 2016
Editorial Board Member: The Open Stem Cell Journal (Journal) 2008 - 2014

Organizer Of Event

Business of Regenerative Medicine Asia-Pacific Symposium 2019 - 2020
28th NSW Stem Cell Network Stem Cell Innovative Technologies Workshop 2018 - 2019
Annual ARC Centre of Excellence for Electromaterials Science Full Centre Meeting - Boot Camp: Training for Translation - 2019
Biological Psychiatry Australia Annual Conference 2016 - 2017
Australasian Society for Stem Cell Research 8th Annual Conference 2014 - 2015
ACES Stem Cells for Bionics Workshop 2014
4th Asia Pacific Symposium on Nanobionics 2013

Professional Service Activities

University of Wollongong Institutional Biosafety Committee Committee Member 2019 -
ARC Centre of Excellence for Electromaterials Science Equity and Diversity Committee Co-Chair 2018 -
Ethical Conduct in Human Research for Use of Human Cell Lines; Human Research Ethics Sub-Committee Committee Member 2017 -
University of Wollongong School of Medicine MEDI400 Honours Program Assessment Committee Member 2017 -
ARC Centre of Excellence for Electromaterials Science. Executive Team Member 2015 - 2016

Outreach And Community Service Activities

International Stem Cell Banking Initiative (ISCBI) Steering Committee Member 2014 -
Connecticut Academy of Science and Engineering (CASE) Stem Cell Research Peer Review Committee Committee Member 2014
UK Medical Research Council’s Molecular and Cellular Medicine Board (MCMB) Committee of Review Committee Member 2013

Education And Training

B.Sc., University of Tasmania, Honours
Ph.D., University of Melbourne, Department of Pathology 1998

Awards And Honors

2021 MedTech Actuator Menzies Fellowship, conferred by MedTech Actuator and Menzies Foundation , 2020
Inaugural Research Australia 2019 Health and Medical Research “Frontiers Research Award”, conferred by Research Australia, 2019
Acknowledgement Letter - Outstanding Student Supervisor , conferred by China Scholarship Council., 2018
Dyason Fellowship , conferred by The University of Melbourne, 2013
Young Investigator Award , conferred by International Congress on Schizophrenia Research, 2001
NIH Fellows Award for Research Excellence , conferred by US National Institutes of Health, 2001
Fogarty International Center Medical Research Fellowship , conferred by Fogarty International Center, National Institutes of Health, 1999
NHMRC “Dora Lush" Postgraduate Research Scholarship, conferred by NHMRC, 1994 - 1998

Teaching Overview

Jeremy is utilising his expertise and research discoveries to provide high-quality interdisciplinary undergraduate and graduate student research training. Training broadly relates to applying new bio- and elecro-material-based strategies (with additive manufacturing) to improve cell delivery and quality of engineered tissues, and attendant bioelectronic devices for clinical application.

Keywords

1. stem cells, 2. neurodevelopmental disorders, 3. tissue engineering, 4. neural regulation, 5. disease modelling, 6. cellular mechanisms, 7. disease mechanisms, 8. neuropsychiatric disorders, 9. neurogenesis, 10. biomaterials, 11. electromaterials, 12. bioelectronics, 13. electroceuticals

Full Name

Jeremy Micah Crook

Mailing Address

Squires Way, AIIM Facility, Innovation Campus

Fairy Meadow

NSW

2519

Austrralia

Located In Facility

Intelligent Polymer Research Institute

Orcid Id

http://orcid.org/0000-0002-6415-1639 (confirmed)

Web Of Science Researcher Id

AAH-8441-2020

Scopus Id

7103400432

Overview

Overview

Top Publications

Research Areas

Research Overview

Geographic Focus

Available as Research Supervisor

Affiliation

Available for Collaborative Projects

Head Of

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Publications

Selected Publications

Journal Article

Book

Chapter

Conference Paper

Other Publications

Editor Of

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Edited Book

Featured In

Funding

Investigator On

Other Research Activities

Impact

Impact Story

Supervision

Available as Research Supervisor

Potential Supervision Topics

Teaching Activities

Advisees

Graduate Advising Relationship

Service

Outreach Overview

Reviewer Of

Organizer Of Event

Professional Service Activities

Outreach And Community Service Activities

Background

Education And Training

Awards And Honors

Teaching Overview

Keywords

Contact

Full Name

Mailing Address

Located In Facility

Identity

Orcid Id

Web Of Science Researcher Id

Scopus Id

Overview

Top Publications

Research Areas

Research Overview

Geographic Focus

Affiliation

Head Of

Member Of

Publications

Selected Publications

Journal Article

Book

Chapter

Conference Paper

Other Publications

Editor Of

Book

Edited Book

Featured In

Funding

Investigator On

Other Research Activities

Impact

Impact Story

Supervision

Potential Supervision Topics

Teaching Activities

Advisees