Crook, Jeremy M. Associate Professor and Principal Fellow

Member Of

• Asian-Pacific Society for Neurochemistry Member 2018 -
• International Society for Neurochemistry Member 2018 -
• Biological Psychiatry Australia Member 2010 -
• Cell Reprogramming Australia Member 2010 -
• Australasian Neuroscience Society Member 2009 -
• Australian Society for Stem Cell Research Member 2009 -
• International Society for Stem Cell Research Member 2006 -

Selected Publications

• Journal Article

  Year	Title
  2020	3D Bioprinting Electrically Conductive Bioink with Human Neural Stem Cells for Human Neural Tissues Published In Methods in Molecular Biology Volume 2140 Pages 159 - 170 ISSN 1064-3745 Altmetric
  2020	Biomimetic corneal stroma using electro-compacted collagen Published In Acta Biomaterialia Volume Online First Altmetric
  2020	Bioprinting 3D Human Induced Pluripotent Stem Cell Constructs for Multilineage Tissue Engineering and Modeling Published In Methods in Molecular Biology Volume 2140 Pages 251 - 258 ISSN 1064-3745 Altmetric
  2020	Cell Processing for 3D Bioprinting: Quality Requirements for Quality Assurance in Fundamental Research and Translation Published In Methods in Molecular Biology Volume 2140 Pages 19 - 26 ISSN 1064-3745 Altmetric
  2020	Electrical stimulation-induced osteogenesis of human adipose derived stem cells using a conductive graphene-cellulose scaffold Published In Materials Science and Engineering C: Materials for Biological Applications Volume 107 Pages 110312-1 - 110312-9 ISSN 0928-4931 Altmetric
  2020	Molecular interactions and forces of adhesion between single human neural stem cells and gelatin methacrylate hydrogels of varying stiffness Published In Acta Biomaterialia Altmetric
  2020	Wet-Spun Trojan Horse Cell Constructs for Engineering Muscle Published In Frontiers in Chemistry Volume 8 Altmetric
  2019	3D graphene-containing structures for tissue engineering Published In Materials Today Chemistry Volume 14 Pages 100199-1 - 100199-11 Altmetric
  2019	Clinically amendable, defined, and rapid induction of human brain organoids from induced pluripotent stem cells Published In BMC Developmental Biology Volume 1576 Pages 13 - 22 ISSN 1471-213X Altmetric
  2019	Human Neural Tissues from Neural Stem Cells Using Conductive Biogel and Printed Polymer Microelectrode Arrays for 3D Electrical Stimulation Published In Advanced Healthcare Materials Volume 8 Pages 1900425-1 - 1900425-10 ISSN 2192-2640 Altmetric
  2019	Smart graphene-cellulose paper for 2D or 3D “origami-inspired” human stem cell support and differentiation Published In Colloids and Surfaces B: Biointerfaces Volume 176 Pages 87 - 95 ISSN 0927-7765 Altmetric
  2018	A Standard Nomenclature for Referencing and Authentication of Pluripotent Stem Cells Published In Stem Cell Reports Volume 10 Pages 1 - 6 Altmetric
  2018	Biomaterials for corneal bioengineering Published In Biomedical Materials Volume 13 Pages 032002-1 - 032002-27 ISSN 1748-6041 Altmetric
  2018	Conductive Tough Hydrogel for Bioapplications Published In Macromolecular Bioscience Volume 18 Pages 1700270-1 - 1700270-11 ISSN 1616-5187 Altmetric
  2018	Three-dimensional neural cultures produce networks that mimic native brain activity Published In Journal of Tissue Engineering and Regenerative Medicine Volume 12 Pages 490 - 493 ISSN 1932-6254 Altmetric
  2017	3D Bioprinting Human Induced Pluripotent Stem Cell Constructs for In Situ Cell Proliferation and Successive Multilineage Differentiation Published In Advanced Healthcare Materials Volume 6 Pages 1700175-1 - 1700175-11 ISSN 2192-2640 Altmetric
  2017	Development of a porous 3D graphene-PDMS scaffold for improved osseointegration Published In Colloids and Surfaces B: Biointerfaces Volume 159 Pages 386 - 393 ISSN 0927-7765 Altmetric
  2017	Development of drug-loaded polymer microcapsules for treatment of epilepsy Published In Biomaterials Science Volume 5 Pages 2159 - 2168 ISSN 2047-4830 Altmetric
  2017	Electrical stimulation using conductive polymer polypyrrole counters reduced neurite outgrowth of primary prefrontal cortical neurons from NRG1-KO and DISC1-LI mice Published In Scientific Reports Volume 7 Pages 42525 -1 - 42525 -8 ISSN 2045-2322 Altmetric
  2017	Electro-mechano responsive properties of gelatin methacrylate (GelMA) hydrogel on conducting polymer electrodes quantified using atomic force microscopy Published In Soft Matter Volume 13 Pages 4761 - 4772 ISSN 1744-683X Altmetric
  2017	Report of the International Stem Cell Banking Initiative Workshop Activity: Current Hurdles and Progress in Seed-Stock Banking of Human Pluripotent Stem Cells Published In Stem Cells Translational Medicine Volume 6 Pages 1956 - 1962 ISSN 2157-6580 Altmetric
  2016	Functional 3D neural mini-tissues from printed gel-based bioink and human neural stem cells Published In Advanced Healthcare Materials Volume 5 Pages 1429 - 1438 ISSN 2192-2640 Altmetric
  2015	Electrical stimulation using conductive polymer polypyrrole promotes differentiation of human neural stem cells: a biocompatible platform for translational neural tissue engineering Published In Tissue Engineering Part C: Methods Volume 21 Pages 385 - 393 ISSN 1937-3384 Altmetric
  2015	Points to consider in the development of seed stocks of pluripotent stem cells for clinical applications: International Stem Cell Banking Initiative (ISCBI) Published In Regenerative Medicine Volume 10 Pages 1 - 44 ISSN 1746-0751 Altmetric
  2015	Pre-differentiation of human neural stem cells into GABAergic neurons prior to transplant results in greater repopulation of the damaged brain and accelerates functional recovery after transient ischemic stroke Published In Stem Cell Research and Therapy Volume 6 Pages 1 - 19 ISSN 1757-6512 Altmetric
  2015	The potential of induced pluripotent stem cells in models of neurological disorders: Implications on future therapy Published In Expert Review of Neurotherapeutics: a key contribution to decision making in the treatment of neurologic and neuropsychiatric disorders Volume 15 Pages 295 - 304 ISSN 1473-7175 Altmetric
  2014	Differentiation of stem cells derived from human infrapatellar fat pad for cartilage engineering: characterisation of cells undergoing chondrogenesis Published In Tissue Engineering Part A Volume 20 Pages 2213 - 2223 ISSN 1937-335X Altmetric
  2013	Banking human induced pluripotent stem cells: lessons learned from embryonic stem cells? Published In Cell Stem Cell Volume 13 Pages 385 - 388 ISSN 1934-5909 Altmetric
  2011	A call for standardized naming and reporting of human ESC and iPSC lines Published In Cell Stem Cell Volume 8 Pages 357 - 359 ISSN 1934-5909 Altmetric
  2011	Human embryonic stem cell therapies for neurodegenerative diseases Published In CNS and Neurological Disorders Volume 10 Pages 440 - 448 ISSN 1996-3181 Altmetric
  2011	Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage Published In Nature Biotechnology Volume 29 Pages 1132 - 1146 ISSN 1087-0156 Altmetric
  2011	Toward clinical application of stem cells for cardiac regeneration Published In Heart Lung and Circulation Volume 20 Pages 173 - 179 ISSN 1443-9506 Altmetric
  2010	G-protein coupled receptors in stem cell self-renewal and differentiation Published In Stem Cell Reviews Volume 6 Pages 351 - 366 ISSN 1550-8943 Altmetric
  2010	Modelling disrupted-in-schizophrenia 1 loss of function in human neural progenitor cells: tools for molecular studies of human neurodevelopment and neuropsychiatric disorders Published In Molecular Psychiatry Volume 15 Pages 672 - 675 ISSN 1359-4184 Altmetric
  2010	Pluripotent human stem cells Published In BioDrugs: clinical immunotherapeutics, biopharmaceuticals and gene therapy Volume 24 Pages 99 - 108 ISSN 1172-7039 Altmetric
  2010	The generation of GLP-grade human embryonic stem cell banks from four clinical-grade cell lines for preclinical research Published In In Vitro Cellular and Developmental Biology: Animal Volume 46 Pages 210 - 216 ISSN 1071-2690 Altmetric
  2008	Attachment and growth of human embryonic stem cells on microcarriers Published In Journal of Biotechnology Volume 138 Pages 24 - 32 ISSN 0168-1656 Altmetric
  2008	Efficient expansion of clinical-grade human fibroblasts on microcarriers: Cells suitable for ex vivo expansion of clinical-grade hESCs Published In Journal of Biotechnology Volume 134 Pages 79 - 87 ISSN 0168-1656 Altmetric
  2008	Human stem cells for modeling neurological disorders: accelerating the drug discovery pipeline Published In Journal of Cellular Biochemistry Volume 105 Pages 1361 - 1366 ISSN 0730-2312 Altmetric
  2008	Metabotropic glutamate receptor 2 and 3 gene expression in the human prefrontal cortex and mesencephalon in schizophrenia Published In International Journal of Neuroscience Volume 118 Pages 1609 - 1627 ISSN 0020-7454 Altmetric

• Chapter

  Year	Title
  2018	Engineering human neural tissue by 3D bioprinting Published In Biomaterials for tissue engineering: methods and protocols Publisher United States: Humana Press, Inc. Pages 129 - 138 ISBN 9781493977413 Altmetric
  2017	Cryobanking Pluripotent Stem Cells Published In Stem Cell Banking: Concepts and Protocols Publisher New York, United States: Humana Press Pages 151 - 164 ISBN 9781493969210 Altmetric
  2017	Culturing and Cryobanking Human Neural Stem Cells Published In Stem Cell Banking: Concepts and Protocols Publisher New York, United States: Humana Press Pages 199 - 206 ISBN 9781493969210 Altmetric
  2017	Derivation of Human Embryonic Stem Cells Published In Stem Cell Banking: Concepts and Protocols Publisher New York, United States: Humana Press Pages 115 - 129 ISBN 9781493969210 Altmetric
  2017	The role of electrical field on stem cells in vitro Published In Conductive Polymers: Electrical Interactions in Cell Biology and Medicine Publisher New York: CRC Press Pages 347 - 372 ISBN 9781482259285
  2014	Setting quality standards for stem cell banking, research and translation: the international stem cell banking initiative Published In Stem Cell Banking Publisher United States: Springer Science+Business Media New York Pages 3 - 9 Altmetric
  2012	Biobanks for pluripotent stem cells Published In Human Stem Cell Manual: A Laboratory Guide Publisher United Kingdom: Elsevier Inc Pages 105 - 125 Altmetric

• Report

  Year	Title
  2019	A Report from a Workshop of the International Stem Cell Banking Initiative, Held in Collaboration of Global Alliance for iPSC Therapies and the Harvard Stem Cell Institute, Boston, 2017 Publisher AlphaMed Press, Inc. Altmetric

Editor Of

• Book

  • Stem cell banking : concepts and protocols.  New York. 2017
  • Crook JM, Ludwig T (Editors) Stem Cell Banking: Concepts & Protocols. Invited book for: Methods in Molecular Biology Series. Humana Press (Springer imprint), New York. 1st Ed. 2017.

• Edited Book

  • Crook JM, Ludwig T (Editors) Stem Cell Banking: Concepts & Protocols. Invited book for: Methods in Molecular Biology Series. Humana Press (Springer imprint), New York. 1st Ed. 2017.

Featured In

• The Illawarra Mercury  Article

Investigator On

Year	Title
2014 - 2020	ARC Centre of Excellence for Electromaterials Science Awarded by: Australian Research Council (ARC) Funding Scheme: Centres of Excellence
2019	Rat activity wheel and living chamber system Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2014 - 2017	Application of intelligent conducting polymers for treating schizophrenia and allied disorders focusing on neuronal outgrowth, myelination and synaptogenesis Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
	3D Additive Bio-Fabrication Facility: Printing Bioprinters Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
	Electrophysiology Facility for Cell Phenotyping and Drug Discovery Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
	Forced exercise/walking wheel system for rats Model 80805A Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant

Other Research Activities

• National Heart Foundation Grant In Aid G09M4399: Tissue Engineering Of Human Cardiac Muscle From Autologous Stem Cells Chief Investigator
• Global Challenges Funding Award: Modelling emergent properties in the brain to combat neurodegenerative disease Named Investigator 2019 - 2020
• ANSTO-UOW Joint Project Seed Funding Award: Chief Investigator –Testing in vivo biocompatibility and osteoinductivity of a 3D graphene scaffold for bone regeneration Chief Investigator 2018 - 2020
• ANSTO-UOW Joint Project Seed Funding Award: In vivo imaging of 3D neural microtissues Chief Investigator 2016 - 2017
• Leadership Fellowship in Stem Cell Medicine – Helen Macpherson Smith Trust & O’Brien Foundation Director 2010 - 2012
• NHMRC Project Grant 628767: Free radicals in Brain Repair After Stroke Chief Investigator 2010 - 2012

Impact Story

Potential Supervision Topics

• Broadly, next generation human tissue building and electroceuticals using front-line technologies stem cells, innovative biomaterials, 3D bioprinting, organoidogenesis and bioelectronics.  

Teaching Activities

• University of Technology Sydney - Engineering 42026 Biomedical Polymers: Polymers for Neural Regeneration Guest Lecturer 2020 -
• AIIM901 Online Biofabrication Course Subject Developer & Facilitator - "Brain On The Bench" 2019 -
• Sydney University - AMME4971/AMME9971 Tissue Engineering: Synthetic Biosystems For 3D Modelling Of Development, Disease & Regenerative Medicine Guest Lecturer 2018 -
• University of Wollongong MEDI400 Medical and Health Science Honours, School of Medicine Honours Program Student Supervisor 2017 -

Advisees

• Graduate Advising Relationship

  Degree	Research Title	Advisee
  Doctor of Philosophy	Modelling Ultrasound Mediated Neuromodulation: Towards Targeted Therapeutic Brain Stimulation	Rathbone, Sam
  Doctor of Philosophy	Electro Stimulation of 3D Bioprinted Neural Tissues	Warren, Danielle
  Doctor of Philosophy	Direct Piezoelectricity for 3D Cardiac Tissue Engineering and Remodelling	James, Emma
  Doctor of Philosophy	Investigating the Therapeutic Effects of Electrical Stimulation on a 3D Human Organoid Glioblastoma Model	Higginbottom, Sarah

Outreach Overview

• To inspire and educate the public by targeted communication about our frontier research undertaken at the University of Wollongong.
  
  Recent media outreach includes:  
  

  1. https://researchaustralia.org/congratulations-to-the-winner-of-the-frontiers-researchaward-
  jeremy-crook-and-team/
  
  2. https://researchaustralia.org/category/news/media/
  
  3. https://www.illawarramercury.com.au/story/6487387/uow-scientists-electrifying-discoveryand-the-conditions-it-could-help/
  
  4. See p8 of Research Australia's INSPIRE Magazine Issue 14: https://issuu.com/researchaustralia/docs/ra0026_inspire_dec19__
  
  5. ACES News: https://electromaterials.edu.au/2019/06/28/prof-jeremy-crook-on-groundbreaking-stem-cell-research-findings/
  
  6. ABC Catalyst Bionic Revolution (from 47 minute mark): https://www.abc.net.au/catalyst/bionic-revolution/11017392
  
  7. Kids News: https://www.kidsnews.com.au/science/australian-scientists-have-grown-minibrains-and-zapped-them-to-life-with-electricity/newsstory/451779e60c2e942553ae06d3ca1f1df0
  
  8. Brigid OConnell: https://twitter.com/BrigidOConnell/status/1202356508882636803
  
  9. Herald Sun: https://www.heraldsun.com.au/subscribe/news/1/?sourceCode=HSWEB_WRE170_a_TWT&dest=https%3A%2F%2Fwww.heraldsun.com.au%2Fnews%2Fvictoria%2Funiversity-ofwollongong-scientists-present-mini-brains-technology%2Fnewsstory%2F960de8f80c166f3e3c4e3b413de53f7f&memtype=anonymous&mode=premium
  
  10. Australasian Neuroscience Society: https://twitter.com/AusNeuroSoc/status/1202423989726892032?s=20
  
  11. Cellink Life Sciences: https://www.cellink.com/close-3d-printing-bodies/
  
  12. ABC News: https://www.abc.net.au/news/science/2017-07-26/scientists-create-3d-printedbrain-like-tissue-from-stem-cells/8740794
  
  13. Advanced Science News: http://www.advancedsciencenews.com/

Reviewer Of

• 3D Bioprinting: Principles and Protocols; Methods in Molecular Biology; Springer Nature  (Edited Book) 2020 -
• Associate Editor: 'Experimental Therapeutics' section of Frontiers in Neurology  (Journal) 2020 -
• Editorial Board Member: Bioprinting  (Journal) 2018 -
• Stem Cell Banking: Concepts & Protocols; Methods in Molecular Biology. Springer Nature  (Edited Book) 2017 -
• Editorial Board Member: BioEssays  (Journal) 2016 -
• Editorial Board Member: The Open Medicine Journal  (Journal) 2015 -
• Editorial Board Member: Data Set Papers in Medicine - Psychiatry  (Journal) 2012 -
• Editorial Board Member: Journal of Cellular Biochemistry  (Journal) 2009 -
• Editorial Board Member: World Stem Cell Journal  (Journal) 2009 -
• Editorial Board Member: Scientifica  (Journal) 2012 - 2017
• Editorial Board Member: Inside the Cell  (Journal) 2014 - 2016
• Editorial Board Member: The Open Stem Cell Journal  (Journal) 2008 - 2014

Organizer Of Event

• Business of Regenerative Medicine Asia-Pacific Symposium 2019 - 2020
• 28th NSW Stem Cell Network Stem Cell Innovative Technologies Workshop 2018 - 2019
• Annual ARC Centre of Excellence for Electromaterials Science Full Centre Meeting - Boot Camp: Training for Translation - 2019
• Biological Psychiatry Australia Annual Conference 2016 - 2017
• Australasian Society for Stem Cell Research 8th Annual Conference 2014 - 2015
• ACES Stem Cells for Bionics Workshop 2014
• 4th Asia Pacific Symposium on Nanobionics 2013

Professional Service Activities

• University of Wollongong Institutional Biosafety Committee Committee Member 2019 -
• ARC Centre of Excellence for Electromaterials Science Equity and Diversity Committee Co-Chair 2018 -
• Ethical Conduct in Human Research for Use of Human Cell Lines; Human Research Ethics Sub-Committee Committee Member 2017 -
• University of Wollongong School of Medicine MEDI400 Honours Program Assessment Committee Member 2017 -
• ARC Centre of Excellence for Electromaterials Science. Executive Team Member 2015 - 2016

Outreach And Community Service Activities

• International Stem Cell Banking Initiative (ISCBI) Steering Committee Member 2014 -
• Connecticut Academy of Science and Engineering (CASE) Stem Cell Research Peer Review Committee Committee Member 2014
• UK Medical Research Council’s Molecular and Cellular Medicine Board (MCMB) Committee of Review Committee Member 2013

Education And Training

• B.Sc., University of Tasmania, Honours
• Ph.D., University of Melbourne, Department of Pathology 1998

Awards And Honors

• Inaugural Research Australia 2019 Health and Medical Research “Frontiers Research Award”, conferred by Research Australia, 2019
• Acknowledgement Letter - Outstanding Student Supervisor , conferred by China Scholarship Council., 2018
• Dyason Fellowship , conferred by The University of Melbourne, 2013
• Young Investigator Award , conferred by International Congress on Schizophrenia Research, 2001
• NIH Fellows Award for Research Excellence , conferred by US National Institutes of Health, 2001
• Fogarty International Center Medical Research Fellowship , conferred by Fogarty International Center, National Institutes of Health, 1999
• NHMRC “Dora Lush" Postgraduate Research Scholarship, conferred by NHMRC, 1994 - 1998

Teaching Overview

• Jeremy is utilising his expertise and research discoveries to provide high-quality interdisciplinary undergraduate and graduate student research training. Training broadly relates to applying new bio- and elecro-material-based strategies (with additive manufacturing) to improve cell delivery and quality of engineered tissues, and attendant bioelectronic devices for clinical application.

Keywords

• 1. stem cells,   2. neurodevelopmental disorders,   3. tissue engineering,   4. neural regulation,   5. disease modelling,   6. cellular mechanisms,   7. disease mechanisms,   8. neuropsychiatric disorders,   9. neurogenesis,   10. biomaterials, 11. electromaterials, 12. bioelectronics, 13. electroceuticals  

Full Name

• Jeremy Micah Crook

Mailing Address

• Squires Way, AIIM Facility, Innovation Campus

  Fairy Meadow

  NSW

  2519

  Austrralia

Located In Facility

• Intelligent Polymer Research Institute 

Orcid Id

• http://orcid.org/0000-0002-6415-1639 (confirmed)

Web Of Science Researcher Id

• AAH-8441-2020

Scopus Id

• 7103400432

Top Publications

Year	Title
2019	Human Neural Tissues from Neural Stem Cells Using Conductive Biogel and Printed Polymer Microelectrode Arrays for 3D Electrical Stimulation Published in   Advanced Healthcare Materials
2010	The generation of GLP-grade human embryonic stem cell banks from four clinical-grade cell lines for preclinical research Published in   In Vitro Cellular and Developmental Biology: Animal
2017	3D Bioprinting Human Induced Pluripotent Stem Cell Constructs for In Situ Cell Proliferation and Successive Multilineage Differentiation Published in   Advanced Healthcare Materials
2016	Functional 3D neural mini-tissues from printed gel-based bioink and human neural stem cells Published in   Advanced Healthcare Materials
2015	Electrical stimulation using conductive polymer polypyrrole promotes differentiation of human neural stem cells: a biocompatible platform for translational neural tissue engineering Published in   Tissue Engineering Part C: Methods
2010	Modelling disrupted-in-schizophrenia 1 loss of function in human neural progenitor cells: tools for molecular studies of human neurodevelopment and neuropsychiatric disorders Published in   Molecular Psychiatry
2008	Attachment and growth of human embryonic stem cells on microcarriers Published in   Journal of Biotechnology

Research Areas

• 0601 - BIOCHEMISTRY AND CELL BIOLOGY
• 060103 - CELL DEVELOPMENT, PROLIFERATION AND DEATH
• 060105 - CELL NEUROCHEMISTRY
• 060111 - SIGNAL TRANSDUCTION
• 0903 - BIOMEDICAL ENGINEERING
• 090301 - BIOMATERIALS
• 090304 - MEDICAL DEVICES
• 1004 - MEDICAL BIOTECHNOLOGY
• 100401 - GENE AND MOLECULAR THERAPY
• 100404 - REGENERATIVE MEDICINE (INCL. STEM CELLS AND TISSUE ENGINEERING)
• 100703 - NANOBIOTECHNOLOGY
• 100705 - NANOELECTRONICS
• 100708 - NANOMATERIALS
• 100709 - NANOMEDICINE
• 1109 - NEUROSCIENCES
• 110902 - CELLULAR NERVOUS SYSTEM
• 110903 - CENTRAL NERVOUS SYSTEM
• 110905 - PERIPHERAL NERVOUS SYSTEM

Research Overview

• Jeremy’s main current research interests are next-generation tissue building and electroceuticals (electric pharmaceuticals) for modelling development and disease, early phase drug discovery, and advanced medicine. His research integrates front-line technologies stem cells, organoidogenesis, cell-instructive bio- and electro-materials, 3D bioprinting and bioelectronics. 
  
  
  

Geographic Focus

• New South Wales  State or Province

Member Of

• Asian-Pacific Society for Neurochemistry Member 2018 -
• International Society for Neurochemistry Member 2018 -
• Biological Psychiatry Australia Member 2010 -
• Cell Reprogramming Australia Member 2010 -
• Australasian Neuroscience Society Member 2009 -
• Australian Society for Stem Cell Research Member 2009 -
• International Society for Stem Cell Research Member 2006 -

Selected Publications

• Journal Article

  Year	Title
  2020	3D Bioprinting Electrically Conductive Bioink with Human Neural Stem Cells for Human Neural Tissues Published In Methods in Molecular Biology Volume 2140 Pages 159 - 170 ISSN 1064-3745 Altmetric
  2020	Biomimetic corneal stroma using electro-compacted collagen Published In Acta Biomaterialia Volume Online First Altmetric
  2020	Bioprinting 3D Human Induced Pluripotent Stem Cell Constructs for Multilineage Tissue Engineering and Modeling Published In Methods in Molecular Biology Volume 2140 Pages 251 - 258 ISSN 1064-3745 Altmetric
  2020	Cell Processing for 3D Bioprinting: Quality Requirements for Quality Assurance in Fundamental Research and Translation Published In Methods in Molecular Biology Volume 2140 Pages 19 - 26 ISSN 1064-3745 Altmetric
  2020	Electrical stimulation-induced osteogenesis of human adipose derived stem cells using a conductive graphene-cellulose scaffold Published In Materials Science and Engineering C: Materials for Biological Applications Volume 107 Pages 110312-1 - 110312-9 ISSN 0928-4931 Altmetric
  2020	Molecular interactions and forces of adhesion between single human neural stem cells and gelatin methacrylate hydrogels of varying stiffness Published In Acta Biomaterialia Altmetric
  2020	Wet-Spun Trojan Horse Cell Constructs for Engineering Muscle Published In Frontiers in Chemistry Volume 8 Altmetric
  2019	3D graphene-containing structures for tissue engineering Published In Materials Today Chemistry Volume 14 Pages 100199-1 - 100199-11 Altmetric
  2019	Clinically amendable, defined, and rapid induction of human brain organoids from induced pluripotent stem cells Published In BMC Developmental Biology Volume 1576 Pages 13 - 22 ISSN 1471-213X Altmetric
  2019	Human Neural Tissues from Neural Stem Cells Using Conductive Biogel and Printed Polymer Microelectrode Arrays for 3D Electrical Stimulation Published In Advanced Healthcare Materials Volume 8 Pages 1900425-1 - 1900425-10 ISSN 2192-2640 Altmetric
  2019	Smart graphene-cellulose paper for 2D or 3D “origami-inspired” human stem cell support and differentiation Published In Colloids and Surfaces B: Biointerfaces Volume 176 Pages 87 - 95 ISSN 0927-7765 Altmetric
  2018	A Standard Nomenclature for Referencing and Authentication of Pluripotent Stem Cells Published In Stem Cell Reports Volume 10 Pages 1 - 6 Altmetric
  2018	Biomaterials for corneal bioengineering Published In Biomedical Materials Volume 13 Pages 032002-1 - 032002-27 ISSN 1748-6041 Altmetric
  2018	Conductive Tough Hydrogel for Bioapplications Published In Macromolecular Bioscience Volume 18 Pages 1700270-1 - 1700270-11 ISSN 1616-5187 Altmetric
  2018	Three-dimensional neural cultures produce networks that mimic native brain activity Published In Journal of Tissue Engineering and Regenerative Medicine Volume 12 Pages 490 - 493 ISSN 1932-6254 Altmetric
  2017	3D Bioprinting Human Induced Pluripotent Stem Cell Constructs for In Situ Cell Proliferation and Successive Multilineage Differentiation Published In Advanced Healthcare Materials Volume 6 Pages 1700175-1 - 1700175-11 ISSN 2192-2640 Altmetric
  2017	Development of a porous 3D graphene-PDMS scaffold for improved osseointegration Published In Colloids and Surfaces B: Biointerfaces Volume 159 Pages 386 - 393 ISSN 0927-7765 Altmetric
  2017	Development of drug-loaded polymer microcapsules for treatment of epilepsy Published In Biomaterials Science Volume 5 Pages 2159 - 2168 ISSN 2047-4830 Altmetric
  2017	Electrical stimulation using conductive polymer polypyrrole counters reduced neurite outgrowth of primary prefrontal cortical neurons from NRG1-KO and DISC1-LI mice Published In Scientific Reports Volume 7 Pages 42525 -1 - 42525 -8 ISSN 2045-2322 Altmetric
  2017	Electro-mechano responsive properties of gelatin methacrylate (GelMA) hydrogel on conducting polymer electrodes quantified using atomic force microscopy Published In Soft Matter Volume 13 Pages 4761 - 4772 ISSN 1744-683X Altmetric
  2017	Report of the International Stem Cell Banking Initiative Workshop Activity: Current Hurdles and Progress in Seed-Stock Banking of Human Pluripotent Stem Cells Published In Stem Cells Translational Medicine Volume 6 Pages 1956 - 1962 ISSN 2157-6580 Altmetric
  2016	Functional 3D neural mini-tissues from printed gel-based bioink and human neural stem cells Published In Advanced Healthcare Materials Volume 5 Pages 1429 - 1438 ISSN 2192-2640 Altmetric
  2015	Electrical stimulation using conductive polymer polypyrrole promotes differentiation of human neural stem cells: a biocompatible platform for translational neural tissue engineering Published In Tissue Engineering Part C: Methods Volume 21 Pages 385 - 393 ISSN 1937-3384 Altmetric
  2015	Points to consider in the development of seed stocks of pluripotent stem cells for clinical applications: International Stem Cell Banking Initiative (ISCBI) Published In Regenerative Medicine Volume 10 Pages 1 - 44 ISSN 1746-0751 Altmetric
  2015	Pre-differentiation of human neural stem cells into GABAergic neurons prior to transplant results in greater repopulation of the damaged brain and accelerates functional recovery after transient ischemic stroke Published In Stem Cell Research and Therapy Volume 6 Pages 1 - 19 ISSN 1757-6512 Altmetric
  2015	The potential of induced pluripotent stem cells in models of neurological disorders: Implications on future therapy Published In Expert Review of Neurotherapeutics: a key contribution to decision making in the treatment of neurologic and neuropsychiatric disorders Volume 15 Pages 295 - 304 ISSN 1473-7175 Altmetric
  2014	Differentiation of stem cells derived from human infrapatellar fat pad for cartilage engineering: characterisation of cells undergoing chondrogenesis Published In Tissue Engineering Part A Volume 20 Pages 2213 - 2223 ISSN 1937-335X Altmetric
  2013	Banking human induced pluripotent stem cells: lessons learned from embryonic stem cells? Published In Cell Stem Cell Volume 13 Pages 385 - 388 ISSN 1934-5909 Altmetric
  2011	A call for standardized naming and reporting of human ESC and iPSC lines Published In Cell Stem Cell Volume 8 Pages 357 - 359 ISSN 1934-5909 Altmetric
  2011	Human embryonic stem cell therapies for neurodegenerative diseases Published In CNS and Neurological Disorders Volume 10 Pages 440 - 448 ISSN 1996-3181 Altmetric
  2011	Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage Published In Nature Biotechnology Volume 29 Pages 1132 - 1146 ISSN 1087-0156 Altmetric
  2011	Toward clinical application of stem cells for cardiac regeneration Published In Heart Lung and Circulation Volume 20 Pages 173 - 179 ISSN 1443-9506 Altmetric
  2010	G-protein coupled receptors in stem cell self-renewal and differentiation Published In Stem Cell Reviews Volume 6 Pages 351 - 366 ISSN 1550-8943 Altmetric
  2010	Modelling disrupted-in-schizophrenia 1 loss of function in human neural progenitor cells: tools for molecular studies of human neurodevelopment and neuropsychiatric disorders Published In Molecular Psychiatry Volume 15 Pages 672 - 675 ISSN 1359-4184 Altmetric
  2010	Pluripotent human stem cells Published In BioDrugs: clinical immunotherapeutics, biopharmaceuticals and gene therapy Volume 24 Pages 99 - 108 ISSN 1172-7039 Altmetric
  2010	The generation of GLP-grade human embryonic stem cell banks from four clinical-grade cell lines for preclinical research Published In In Vitro Cellular and Developmental Biology: Animal Volume 46 Pages 210 - 216 ISSN 1071-2690 Altmetric
  2008	Attachment and growth of human embryonic stem cells on microcarriers Published In Journal of Biotechnology Volume 138 Pages 24 - 32 ISSN 0168-1656 Altmetric
  2008	Efficient expansion of clinical-grade human fibroblasts on microcarriers: Cells suitable for ex vivo expansion of clinical-grade hESCs Published In Journal of Biotechnology Volume 134 Pages 79 - 87 ISSN 0168-1656 Altmetric
  2008	Human stem cells for modeling neurological disorders: accelerating the drug discovery pipeline Published In Journal of Cellular Biochemistry Volume 105 Pages 1361 - 1366 ISSN 0730-2312 Altmetric
  2008	Metabotropic glutamate receptor 2 and 3 gene expression in the human prefrontal cortex and mesencephalon in schizophrenia Published In International Journal of Neuroscience Volume 118 Pages 1609 - 1627 ISSN 0020-7454 Altmetric

• Chapter

  Year	Title
  2018	Engineering human neural tissue by 3D bioprinting Published In Biomaterials for tissue engineering: methods and protocols Publisher United States: Humana Press, Inc. Pages 129 - 138 ISBN 9781493977413 Altmetric
  2017	Cryobanking Pluripotent Stem Cells Published In Stem Cell Banking: Concepts and Protocols Publisher New York, United States: Humana Press Pages 151 - 164 ISBN 9781493969210 Altmetric
  2017	Culturing and Cryobanking Human Neural Stem Cells Published In Stem Cell Banking: Concepts and Protocols Publisher New York, United States: Humana Press Pages 199 - 206 ISBN 9781493969210 Altmetric
  2017	Derivation of Human Embryonic Stem Cells Published In Stem Cell Banking: Concepts and Protocols Publisher New York, United States: Humana Press Pages 115 - 129 ISBN 9781493969210 Altmetric
  2017	The role of electrical field on stem cells in vitro Published In Conductive Polymers: Electrical Interactions in Cell Biology and Medicine Publisher New York: CRC Press Pages 347 - 372 ISBN 9781482259285
  2014	Setting quality standards for stem cell banking, research and translation: the international stem cell banking initiative Published In Stem Cell Banking Publisher United States: Springer Science+Business Media New York Pages 3 - 9 Altmetric
  2012	Biobanks for pluripotent stem cells Published In Human Stem Cell Manual: A Laboratory Guide Publisher United Kingdom: Elsevier Inc Pages 105 - 125 Altmetric

• Report

  Year	Title
  2019	A Report from a Workshop of the International Stem Cell Banking Initiative, Held in Collaboration of Global Alliance for iPSC Therapies and the Harvard Stem Cell Institute, Boston, 2017 Publisher AlphaMed Press, Inc. Altmetric

Editor Of

• Book

  • Stem cell banking : concepts and protocols.  New York. 2017
  • Crook JM, Ludwig T (Editors) Stem Cell Banking: Concepts & Protocols. Invited book for: Methods in Molecular Biology Series. Humana Press (Springer imprint), New York. 1st Ed. 2017.

• Edited Book

  • Crook JM, Ludwig T (Editors) Stem Cell Banking: Concepts & Protocols. Invited book for: Methods in Molecular Biology Series. Humana Press (Springer imprint), New York. 1st Ed. 2017.

Featured In

• The Illawarra Mercury  Article

Investigator On

Year	Title
2014 - 2020	ARC Centre of Excellence for Electromaterials Science Awarded by: Australian Research Council (ARC) Funding Scheme: Centres of Excellence
2019	Rat activity wheel and living chamber system Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2014 - 2017	Application of intelligent conducting polymers for treating schizophrenia and allied disorders focusing on neuronal outgrowth, myelination and synaptogenesis Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
	3D Additive Bio-Fabrication Facility: Printing Bioprinters Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
	Electrophysiology Facility for Cell Phenotyping and Drug Discovery Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
	Forced exercise/walking wheel system for rats Model 80805A Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant

Other Research Activities

• National Heart Foundation Grant In Aid G09M4399: Tissue Engineering Of Human Cardiac Muscle From Autologous Stem Cells Chief Investigator
• Global Challenges Funding Award: Modelling emergent properties in the brain to combat neurodegenerative disease Named Investigator 2019 - 2020
• ANSTO-UOW Joint Project Seed Funding Award: Chief Investigator –Testing in vivo biocompatibility and osteoinductivity of a 3D graphene scaffold for bone regeneration Chief Investigator 2018 - 2020
• ANSTO-UOW Joint Project Seed Funding Award: In vivo imaging of 3D neural microtissues Chief Investigator 2016 - 2017
• Leadership Fellowship in Stem Cell Medicine – Helen Macpherson Smith Trust & O’Brien Foundation Director 2010 - 2012
• NHMRC Project Grant 628767: Free radicals in Brain Repair After Stroke Chief Investigator 2010 - 2012

Impact Story

Potential Supervision Topics

• Broadly, next generation human tissue building and electroceuticals using front-line technologies stem cells, innovative biomaterials, 3D bioprinting, organoidogenesis and bioelectronics.  

Teaching Activities

• University of Technology Sydney - Engineering 42026 Biomedical Polymers: Polymers for Neural Regeneration Guest Lecturer 2020 -
• AIIM901 Online Biofabrication Course Subject Developer & Facilitator - "Brain On The Bench" 2019 -
• Sydney University - AMME4971/AMME9971 Tissue Engineering: Synthetic Biosystems For 3D Modelling Of Development, Disease & Regenerative Medicine Guest Lecturer 2018 -
• University of Wollongong MEDI400 Medical and Health Science Honours, School of Medicine Honours Program Student Supervisor 2017 -

Advisees

• Graduate Advising Relationship

  Degree	Research Title	Advisee
  Doctor of Philosophy	Modelling Ultrasound Mediated Neuromodulation: Towards Targeted Therapeutic Brain Stimulation	Rathbone, Sam
  Doctor of Philosophy	Electro Stimulation of 3D Bioprinted Neural Tissues	Warren, Danielle
  Doctor of Philosophy	Direct Piezoelectricity for 3D Cardiac Tissue Engineering and Remodelling	James, Emma
  Doctor of Philosophy	Investigating the Therapeutic Effects of Electrical Stimulation on a 3D Human Organoid Glioblastoma Model	Higginbottom, Sarah

Outreach Overview

• To inspire and educate the public by targeted communication about our frontier research undertaken at the University of Wollongong.
  
  Recent media outreach includes:  
  

  1. https://researchaustralia.org/congratulations-to-the-winner-of-the-frontiers-researchaward-
  jeremy-crook-and-team/
  
  2. https://researchaustralia.org/category/news/media/
  
  3. https://www.illawarramercury.com.au/story/6487387/uow-scientists-electrifying-discoveryand-the-conditions-it-could-help/
  
  4. See p8 of Research Australia's INSPIRE Magazine Issue 14: https://issuu.com/researchaustralia/docs/ra0026_inspire_dec19__
  
  5. ACES News: https://electromaterials.edu.au/2019/06/28/prof-jeremy-crook-on-groundbreaking-stem-cell-research-findings/
  
  6. ABC Catalyst Bionic Revolution (from 47 minute mark): https://www.abc.net.au/catalyst/bionic-revolution/11017392
  
  7. Kids News: https://www.kidsnews.com.au/science/australian-scientists-have-grown-minibrains-and-zapped-them-to-life-with-electricity/newsstory/451779e60c2e942553ae06d3ca1f1df0
  
  8. Brigid OConnell: https://twitter.com/BrigidOConnell/status/1202356508882636803
  
  9. Herald Sun: https://www.heraldsun.com.au/subscribe/news/1/?sourceCode=HSWEB_WRE170_a_TWT&dest=https%3A%2F%2Fwww.heraldsun.com.au%2Fnews%2Fvictoria%2Funiversity-ofwollongong-scientists-present-mini-brains-technology%2Fnewsstory%2F960de8f80c166f3e3c4e3b413de53f7f&memtype=anonymous&mode=premium
  
  10. Australasian Neuroscience Society: https://twitter.com/AusNeuroSoc/status/1202423989726892032?s=20
  
  11. Cellink Life Sciences: https://www.cellink.com/close-3d-printing-bodies/
  
  12. ABC News: https://www.abc.net.au/news/science/2017-07-26/scientists-create-3d-printedbrain-like-tissue-from-stem-cells/8740794
  
  13. Advanced Science News: http://www.advancedsciencenews.com/

Reviewer Of

• 3D Bioprinting: Principles and Protocols; Methods in Molecular Biology; Springer Nature  (Edited Book) 2020 -
• Associate Editor: 'Experimental Therapeutics' section of Frontiers in Neurology  (Journal) 2020 -
• Editorial Board Member: Bioprinting  (Journal) 2018 -
• Stem Cell Banking: Concepts & Protocols; Methods in Molecular Biology. Springer Nature  (Edited Book) 2017 -
• Editorial Board Member: BioEssays  (Journal) 2016 -
• Editorial Board Member: The Open Medicine Journal  (Journal) 2015 -
• Editorial Board Member: Data Set Papers in Medicine - Psychiatry  (Journal) 2012 -
• Editorial Board Member: Journal of Cellular Biochemistry  (Journal) 2009 -
• Editorial Board Member: World Stem Cell Journal  (Journal) 2009 -
• Editorial Board Member: Scientifica  (Journal) 2012 - 2017
• Editorial Board Member: Inside the Cell  (Journal) 2014 - 2016
• Editorial Board Member: The Open Stem Cell Journal  (Journal) 2008 - 2014

Organizer Of Event

• Business of Regenerative Medicine Asia-Pacific Symposium 2019 - 2020
• 28th NSW Stem Cell Network Stem Cell Innovative Technologies Workshop 2018 - 2019
• Annual ARC Centre of Excellence for Electromaterials Science Full Centre Meeting - Boot Camp: Training for Translation - 2019
• Biological Psychiatry Australia Annual Conference 2016 - 2017
• Australasian Society for Stem Cell Research 8th Annual Conference 2014 - 2015
• ACES Stem Cells for Bionics Workshop 2014
• 4th Asia Pacific Symposium on Nanobionics 2013

Professional Service Activities

• University of Wollongong Institutional Biosafety Committee Committee Member 2019 -
• ARC Centre of Excellence for Electromaterials Science Equity and Diversity Committee Co-Chair 2018 -
• Ethical Conduct in Human Research for Use of Human Cell Lines; Human Research Ethics Sub-Committee Committee Member 2017 -
• University of Wollongong School of Medicine MEDI400 Honours Program Assessment Committee Member 2017 -
• ARC Centre of Excellence for Electromaterials Science. Executive Team Member 2015 - 2016

Outreach And Community Service Activities

• International Stem Cell Banking Initiative (ISCBI) Steering Committee Member 2014 -
• Connecticut Academy of Science and Engineering (CASE) Stem Cell Research Peer Review Committee Committee Member 2014
• UK Medical Research Council’s Molecular and Cellular Medicine Board (MCMB) Committee of Review Committee Member 2013

Education And Training

• B.Sc., University of Tasmania, Honours
• Ph.D., University of Melbourne, Department of Pathology 1998

Awards And Honors

• Inaugural Research Australia 2019 Health and Medical Research “Frontiers Research Award”, conferred by Research Australia, 2019
• Acknowledgement Letter - Outstanding Student Supervisor , conferred by China Scholarship Council., 2018
• Dyason Fellowship , conferred by The University of Melbourne, 2013
• Young Investigator Award , conferred by International Congress on Schizophrenia Research, 2001
• NIH Fellows Award for Research Excellence , conferred by US National Institutes of Health, 2001
• Fogarty International Center Medical Research Fellowship , conferred by Fogarty International Center, National Institutes of Health, 1999
• NHMRC “Dora Lush" Postgraduate Research Scholarship, conferred by NHMRC, 1994 - 1998

Teaching Overview

• Jeremy is utilising his expertise and research discoveries to provide high-quality interdisciplinary undergraduate and graduate student research training. Training broadly relates to applying new bio- and elecro-material-based strategies (with additive manufacturing) to improve cell delivery and quality of engineered tissues, and attendant bioelectronic devices for clinical application.

Keywords

• 1. stem cells,   2. neurodevelopmental disorders,   3. tissue engineering,   4. neural regulation,   5. disease modelling,   6. cellular mechanisms,   7. disease mechanisms,   8. neuropsychiatric disorders,   9. neurogenesis,   10. biomaterials, 11. electromaterials, 12. bioelectronics, 13. electroceuticals  

Full Name

• Jeremy Micah Crook

Mailing Address

• Squires Way, AIIM Facility, Innovation Campus

  Fairy Meadow

  NSW

  2519

  Austrralia

Located In Facility

• Intelligent Polymer Research Institute 

Orcid Id

• http://orcid.org/0000-0002-6415-1639 (confirmed)

Web Of Science Researcher Id

• AAH-8441-2020

Scopus Id

• 7103400432