Unified model for group A streptococcal invasive disease initiation

Scheme

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• Project Grant

Abstract

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• A unified model for Streptococcus pyogenes (Streptococcus pyogenes; GAS) invasive disease initiation is under investigation. We hypothesise (1) that the human plasminogen (Plg) system plays a crucial role in GAS invasive disease and (2) that neutrophil killing of GAS at the site of infection, inadvertently selects for an invasive GAS phenotype.

Date/time Interval

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• 2007

Research Areas

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• 110801 - MEDICAL BACTERIOLOGY

Awarded By

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• National Health and Medical Research Council (NHMRC) 

Contributor

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• McArthur, Jason D. - Chief Investigator
• Ranson, Marie - Chief Investigator

Sponsor Award Id

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• 459103

Local Award Id

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• 9037