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Pushing the Limits of Fluorescence Microscopy with Adaptive Optics

Grant


Scheme


  • Linkage Infrastructure Equipment & Facilities (LIEF)

Abstract


  • his project aims to establish an adaptive optics, super-resolution optical microscopy facility to image cellular events with the highest possible spatial resolution, in a whole cell or tissue context. Sophisticated computer-controlled deformable mirrors will be used to correct the way light is distorted as it passes through specimens, thereby overcoming aberrations found in thick and complex samples. This adaptive optics system will enable researchers to study complex behaviour of biological specimens, at the optical resolution limit in plant and animal tissues, leading to basic biology and biotechnology outcomes in biofuels, biomaterials and biomedicines.

Sponsor Award Id


  • LE180100001

Local Award Id


  • 124970

Scheme


  • Linkage Infrastructure Equipment & Facilities (LIEF)

Abstract


  • his project aims to establish an adaptive optics, super-resolution optical microscopy facility to image cellular events with the highest possible spatial resolution, in a whole cell or tissue context. Sophisticated computer-controlled deformable mirrors will be used to correct the way light is distorted as it passes through specimens, thereby overcoming aberrations found in thick and complex samples. This adaptive optics system will enable researchers to study complex behaviour of biological specimens, at the optical resolution limit in plant and animal tissues, leading to basic biology and biotechnology outcomes in biofuels, biomaterials and biomedicines.

Sponsor Award Id


  • LE180100001

Local Award Id


  • 124970