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Understanding the mechanisms of functionally selective drugs: implication for new generation antipsychotic drugs

Grant


Scheme


  • Project Grant

Abstract


  • Schizophrenia is a chronic and devastating disease, affecting approximately 1% of the population worldwide, and ranks among the top 10 disabilities in developed countries. It places a significant burden on the Australian health system, costing about $1.5 billion each year. One critical problem is that control of schizophrenia symptoms involves a lifetime of large doses of antipsychotic drugs. Unfortunately, the drugs currently in use have a range of serious side effects. There is an urgent need for the development of an antipsychotic drug with a maximal therapeutic efficacy but minimal side-effects.

Date/time Interval


  • 2011

Sponsor Award Id


  • APP1008473

Local Award Id


  • 11819

Scheme


  • Project Grant

Abstract


  • Schizophrenia is a chronic and devastating disease, affecting approximately 1% of the population worldwide, and ranks among the top 10 disabilities in developed countries. It places a significant burden on the Australian health system, costing about $1.5 billion each year. One critical problem is that control of schizophrenia symptoms involves a lifetime of large doses of antipsychotic drugs. Unfortunately, the drugs currently in use have a range of serious side effects. There is an urgent need for the development of an antipsychotic drug with a maximal therapeutic efficacy but minimal side-effects.

Date/time Interval


  • 2011

Sponsor Award Id


  • APP1008473

Local Award Id


  • 11819