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Identifying tear lipids, their deposition onto contact lenses and their role in the development of dry eye

Grant


Scheme


  • Linkage Projects

Abstract


  • Changes in the lipid components of human tears are associated with dry eye and contact lens discomfort. Powerful mass spectrometry-based methods developed at the University of Wollongong will be utilized to obtain the first comprehensive profile of the lipids in human tears. In collaboration with the partner organisation, changes in the tear lipidome associated with dry eye and aging will be identified and the lipid deposits on used contact lenses will be characterised. The changes observed, will provide a molecular basis for developing new diagnostic tools and treatments for dry eye syndrome and optimising of contact lens design.

Date/time Interval


  • 2009

Sponsor Award Id


  • LP0989883

Local Award Id


  • 10565

Scheme


  • Linkage Projects

Abstract


  • Changes in the lipid components of human tears are associated with dry eye and contact lens discomfort. Powerful mass spectrometry-based methods developed at the University of Wollongong will be utilized to obtain the first comprehensive profile of the lipids in human tears. In collaboration with the partner organisation, changes in the tear lipidome associated with dry eye and aging will be identified and the lipid deposits on used contact lenses will be characterised. The changes observed, will provide a molecular basis for developing new diagnostic tools and treatments for dry eye syndrome and optimising of contact lens design.

Date/time Interval


  • 2009

Sponsor Award Id


  • LP0989883

Local Award Id


  • 10565