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Regional facility for real time analysis of molecular interactions

Grant


Scheme


  • Linkage Infrastructure Equipment & Facilities (LIEF)

Abstract


  • Macromolecular interactions control life processes. Priority research in three Universities is supported by a shared facility at ANU and the University of Wollongong for the analysis of interactions of biological macromolecules with ligands including proteins, nucleic acids, small molecules and drugs. Acquisition of surface plasmon resonance biosensor and dynamic light scattering capabilities will enable characterization of protein complexes and real time measurement of the rates and stabilities of interactions under various experimental conditions. This will improve understanding of the fundamental chemistry that underlies important biological processes and facilitate collaborative projects in structural biology and drug discovery.

Date/time Interval


  • 2009

Sponsor Award Id


  • LE0989077

Local Award Id


  • 10527

Scheme


  • Linkage Infrastructure Equipment & Facilities (LIEF)

Abstract


  • Macromolecular interactions control life processes. Priority research in three Universities is supported by a shared facility at ANU and the University of Wollongong for the analysis of interactions of biological macromolecules with ligands including proteins, nucleic acids, small molecules and drugs. Acquisition of surface plasmon resonance biosensor and dynamic light scattering capabilities will enable characterization of protein complexes and real time measurement of the rates and stabilities of interactions under various experimental conditions. This will improve understanding of the fundamental chemistry that underlies important biological processes and facilitate collaborative projects in structural biology and drug discovery.

Date/time Interval


  • 2009

Sponsor Award Id


  • LE0989077

Local Award Id


  • 10527